BioSIS 360 Ampoule 30ml
Niacinamide sits ninth on this 30 ml ampoule's 58 entry list and nicotinamide mononucleotide fiftieth, with beta-carotene forty-seventh and two carrot fractions, root extract and seed oil, at fifteen and twenty-two. Huxley, at the treatment step. Korean-market formula.
No reviews yet30 ml
$233.33 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Congested skinUneven textureDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Niacinamide in an ampouleRoutines that want Niacinamide and Adenosine in one stepFilling the ampoule step with a Korean-market formulaAnyone who wants the Niacinamide ampoule sold on Korean shelves
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The BioSIS 360 Ampoule is a 30ml ampoule, used after toner and before moisturizer, morning and evening. The active it is built around is Niacinamide, named ninth on its own ingredient list. The same list carries Adenosine, Nicotinamide Mononucleotide and Beta-Carotene, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the ampoule format rather than by the list alone. This is the Original Korean Formula, the ampoule Huxley sells in Korea, Niacinamide and all.
Key benefits
- Niacinamide, the active this ampoule is built around
- Adenosine and Nicotinamide Mononucleotide on the same list, actives
- Beta-Carotene and Tocopheryl Acetate on the same list, antioxidants
- Tocopherol and Ascorbic Acid further down the same list
- Ascorbyl Tetraisopalmitate and Collagen further down the same list
- Niacinamide named ninth on the manufacturer list printed on this page
Inside the formula
Inside the formula
Where does this ampoule go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than an ampoule goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Niacinamide and not three changes at once.
Is this the Korean-market ampoule or a US version?
The Korean-market one, Niacinamide and all. We match this ampoule to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Niacinamide?
Adenosine, Nicotinamide Mononucleotide and Beta-Carotene. The order they are printed in on this ampoule's panel is the order on the box, so you can see where Niacinamide sits relative to them. Further down the same panel: Tocopheryl Acetate, Tocopherol and Ascorbic Acid.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (58): Water, Glycereth-26, Dipropylene Glycol, Glycerin, Methylpropanediol, Butylene Glycol, 1,2-Hexanediol, Betaine, Niacinamide, Caprylic/Capric Triglyceride, Chondrus Crispus Extract, Saccharum Officinarum (sugarcane) Extract, Castor Oil/Ipdi Copolymer, Sodium Hyaluronate, Daucus Carota Sativa (carrot) Root Extract, Canola Oil, Theobroma Cacao (cocoa) Extract, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Daucus Carota Sativa (carrot) Seed Oil, Melia Azadirachta Leaf Extract, Curcuma Longa (turmeric) Root Extract, Corallina Officinalis Extract, Acetyl Myricetin, Myricetin, Helianthus Annuus (sunflower) Seed Oil, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Collagen, Collagen Extract, Soluble Collagen, Centella Asiatica Extract, Diglycerin, Isononyl Isononanoate, Panthenol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, C12-14 Alketh-12, Tromethamine, Ethylhexylglycerin, Adenosine, Sodium Phytate, Dextrin, Arginine, Beta-Glucan, Amodimethicone, Beta-Carotene, Tocopheryl Acetate, Tocopherol, Nicotinamide Mononucleotide, Ascorbic Acid, Mannitol, Lactic Acid/Glycolic Acid Copolymer, Ascorbyl Tetraisopalmitate, Lecithin, Sodium Acetylated Hyaluronate, Carbomer, Polyvinyl Alcohol
Ingredient list read from huxley.co.kr on 30 August 2026.
54 of 58 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Glycereth-26 humectant
- Glycereth-26 is a modified glycerin that hydrates with far less stickiness than glycerin itself. It is a common way to load water into a formula that has to stay light.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Methylpropanediol humectant
- Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Betaine humectant
- Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Caprylic/Capric Triglyceride emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- Chondrus Crispus Extract plant extract
- Chondrus Crispus is Irish moss, a red seaweed. It is loaded with carrageenan, so it hydrates and thickens at once, and it leaves a cushioned, slippery film.
- Saccharum Officinarum (sugarcane) Extract plant extract
- Sugarcane Extract carries natural glycolic acid and sugars. In cosmetics it is used as a humectant; the acid content is far too low to work as an exfoliant.
42 more explained
- Castor Oil/Ipdi Copolymer film former
- A polymer built from castor oil. It forms a flexible, glossy film, so it is used in lip and long-wear formulas for shine and staying power.
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- Daucus Carota Sativa (carrot) Root Extract plant extract
- Carrot Root Extract carries carotenoids, which give it a strong orange colour. It is used as an antioxidant extract and can tint a formula.
- Canola Oil emollient
- Canola Oil is pressed from rapeseed. It is a light, high-oleic oil used to soften skin and to carry oil-soluble ingredients.
- Theobroma Cacao (cocoa) Extract plant extract
- Cocoa Extract carries polyphenols and a little caffeine. It is used as an antioxidant plant extract and gives a faint warm tint.
- Coccinia Indica Fruit Extract plant extract
- Coccinia Indica is ivy gourd. Its fruit extract is used as a conditioning, hydrating plant extract in Korean formulas.
- Eclipta Prostrata Extract plant extract
- Eclipta Prostrata is false daisy, long used in Ayurvedic and East Asian practice. Its extract is used as a conditioning plant extract, most often in scalp and hair formulas.
- Melia Azadirachta Flower Extract plant extract
- Melia Azadirachta is neem. Its leaf and flower extracts are long-standing Ayurvedic ingredients, and Korean formulas use them in products aimed at the look of congested, blemish-prone skin.
- Ocimum Sanctum Leaf Extract plant extract
- Ocimum Sanctum is holy basil, or tulsi. Its leaf extract carries plant antioxidants and is used in formulas built for the look of stressed, reactive skin.
- Daucus Carota Sativa (carrot) Seed Oil emollient
- Carrot seed oil, pressed from the seed rather than the root. It is used as a conditioning oil and carries its own earthy scent.
- Curcuma Longa (turmeric) Root Extract plant extract
- Turmeric Root Extract carries curcuminoids, well studied plant antioxidants. It is used for the look of dullness and uneven tone, and it tints a formula faintly yellow.
- Corallina Officinalis Extract plant extract
- Corallina Officinalis is coral seaweed, which holds calcium and magnesium in its structure. Its extract is used as a mineral-rich conditioning ingredient.
- Helianthus Annuus (sunflower) Seed Oil emollient
- Sunflower Seed Oil is high in linoleic acid, the fatty acid dry and blemish-prone skin is often short of. It is a light, non-fragrant emollient and one of the better tolerated plant oils.
- Candida Bombicola/Glucose/Methyl Rapeseedate Ferment ferment
- This ferment produces sophorolipids, sugar-based molecules that behave as very mild surfactants and emulsifiers. It is used to keep a formula blended without a harsh cleanser.
- Collagen protein
- Collagen is the structural protein that makes up most of the dermis. Applied on top it is far too large to enter skin, so in a formula it works as a humectant and a smoothing film former.
- Collagen Extract protein
- Collagen Extract is a collagen-bearing extract, usually from fish skin or scales. In a formula it works as a humectant and a smoothing film rather than as a source of new collagen.
- Soluble Collagen protein
- Soluble Collagen is collagen kept in its intact triple-helix form and dissolved rather than cut up. It sits on the surface as a water-holding film.
- Centella Asiatica Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Diglycerin humectant
- Diglycerin is two glycerin units joined together. It holds water like glycerin but feels less tacky, so it is used where a formula needs hydration without drag.
- Isononyl Isononanoate emollient
- Isononyl Isononanoate is a branched ester used as a dry emollient. It spreads far for its weight and leaves almost no residue, which is why it appears in formulas that have to feel weightless.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Ammonium Acryloyldimethyltaurate/Vp Copolymer thickener
- This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
- C12-14 Alketh-12 emulsifier
- C12-14 Alketh-12 is a solubiliser used to keep oils and fragrance dissolved in a water-based formula.
- Tromethamine pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Sodium Phytate chelator
- Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
- Dextrin thickener
- Dextrin is a starch fragment used to thicken and to give a formula a light, powdery finish. It is also a common carrier for powdered extracts.
- Arginine amino acid
- Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
- Beta-Glucan polysaccharide
- Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
- Amodimethicone silicone
- A silicone carrying a positive charge, so it is drawn to damaged hair and stays after rinsing. It is a conditioning silicone rather than a slip agent.
- Beta-Carotene antioxidant
- Beta-Carotene is an orange plant pigment and a vitamin A precursor. It is used as an antioxidant and it tints a formula, which is often why it is there.
- Tocopheryl Acetate antioxidant
- Tocopheryl Acetate is a stable vitamin E ester that skin converts to tocopherol. It is used as an antioxidant and a light emollient and holds up better than plain vitamin E in a formula.
- Tocopherol antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- Nicotinamide Mononucleotide active
- Nicotinamide Mononucleotide is a nucleotide built from vitamin B3 and a sugar phosphate. Korean formulas use it as a conditioning active, usually alongside niacinamide itself.
- Ascorbic Acid antioxidant
- Ascorbic Acid is pure vitamin C, the most researched form and also the least stable: it needs a low pH and airtight packaging to stay active. It is an antioxidant used for the look of dullness and uneven tone.
- Mannitol humectant
- Mannitol is a sugar alcohol used as a humectant and antioxidant. It hydrates and helps stabilise the rest of the formula against oxidation.
- Ascorbyl Tetraisopalmitate antioxidant
- Ascorbyl Tetraisopalmitate is an oil-soluble vitamin C ester, also sold as tetrahexyldecyl ascorbate. Being oil soluble it sits in the oil phase and is far more stable than pure vitamin C.
- Lecithin emulsifier
- Lecithin is a soy or sunflower-derived phospholipid, the same class of molecule cell membranes are built from. It emulsifies oil into water and is the basis of the liposomes formulators use to carry actives.
- Sodium Acetylated Hyaluronate humectant
- Sodium Acetylated Hyaluronate is hyaluronic acid modified to be part oil-loving, so it clings to skin instead of rinsing away. Formulators call it the one that stays put.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
- Polyvinyl Alcohol film former
- Polyvinyl Alcohol is the polymer behind peel-off masks: it dries into a continuous film that lifts away in one piece.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809422539097
- Made in
- Republic of Korea
- Volume
- 30 ml
- Category
- Serum & Ampoule
- Actives
- Adenosine, Beta-Glucan, Centella Asiatica, Collagen, Glycolic Acid, Lactic Acid, Niacinamide, Panthenol, Sodium Hyaluronate, Vitamin C
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Use it as the targeted treatment step, PM, or AM under sunscreen, layered after toner, giving it a moment to settle before the next step.
Worth knowing
- Patch test this ampoule on a small area and wait a day before using it more widely, especially with Niacinamide on the list.
- Introduce this ampoule on its own for the first week, so anything your skin does is traceable to the Niacinamide rather than to three changes at once.
Complete the routine
- This itemHuxley BioSIS 360 Ampoule 30ml$70.00

- Cleanse first, so the next step meets bare skinHuxley Cleansing Gel ; Be Clean, Be Moist 200ml$47.50

- Prep after cleansing, before the treatment stepHuxley Toner ; Extract It 120ml$47.50

Total for 3 items$165.00
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Huxley BioSIS 360 Ampoule 30ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
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Huxley, Korean-market original
The Original Korean Formula ampoule from Huxley, 30ml formulated with Niacinamide and Adenosine, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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