What does the Soyxidil Shampoo 490ml actually contain?

Its ingredient list is led by Melaleuca Alternifolia (Tea Tree) Extract, with the rest of the formula built to support that active rather than compete with it. We list the ingredients in the order the manufacturer prints them, so the ones near the top of the panel are doing the most work in the formula.

How do I use the Soyxidil Shampoo 490ml?

Use this shampoo as the cleansing step of a hair-care routine. To apply, work a coin-sized amount into wet hair and scalp, lather, and rinse thoroughly. Keep it to as often as the scalp needs washing unless the packaging states otherwise, and give the rest of the routine a moment to settle before layering the next step. Give it a full bottle or box before judging the result, since most Korean routines are built for steady use rather than a single application.

Is the Soyxidil Shampoo 490ml the same formula sold in Korea, or a US version?

This Soyxidil Shampoo 490ml is the Korean-market formula, not a version reformulated for US shelves. It arrives with its original Korean-market barcode and batch code intact so the formula can be checked against the box on arrival.

Can I use the Soyxidil Shampoo 490ml with other actives in my routine?

Yes, as long as it is used in its own step, the cleansing step of a hair-care routine, and not layered on top of a product doing the same job. Introduce any new step gradually over the first week or two and keep an eye on how the skin responds before adding a second new active alongside it.

Who is the Soyxidil Shampoo 490ml suited for?

It suits most skin types looking for cleansing step of hair-care routine rather than a single acute problem. It comes in a 490ml format. Anyone with a known sensitivity to a specific ingredient should check the full ingredient panel on this page before buying.

Medicube

Soyxidil Shampoo 490ml

Name: Medicube Soyxidil Shampoo 490ml
Brand: Medicube
SKU: medicube755
Price: 47.5 USD
Availability: InStock

Medicube Soyxidil Shampoo 490ml is a Korean-market shampoo built around Melaleuca Alternifolia (Tea Tree) Extract, formulated in Korea and sold here in its original Korean-market formula rather than a US-shelf reformulation.

Reviewed by Nurcan Saglam, licensed dermo-cosmetic expert (Paris)

No reviews yet

$47.50

490 ml

$9.69 per 100 ml

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: a normal scalpan oily scalpa dry, flaking scalp

Helps with: scalp itchiness or buildupfine or thinning-feeling haira scalp that gets oily between washes

In stock. Arrives in 3 to 7 business days

You’re $100.00 away from free US shipping.

30-day returns
Free US shipping on orders of $100 or more
Tracked delivery to your door

Verified authentic Shipping and returns

How it works

Medicube Soyxidil Shampoo 490ml is a shampoo built for the cleansing step of a hair-care routine. Its ingredient list leads with Melaleuca Alternifolia (Tea Tree) Extract, Ascorbic Acid, and 3-O-Ethyl Ascorbic Acid, so the formula's stated purpose lines up with what actually sits near the top of that list rather than with a single marketing ingredient buried further down. Melaleuca Alternifolia (Tea Tree) Extract does the most work here as a clarity, and the remaining actives round out the texture and finish rather than compete for attention. Placed as the cleansing step of a hair-care routine, it is meant to be used as often as the scalp needs washing rather than swapped freely between steps. Because this is the Korean-market version of the Soyxidil Shampoo 490ml line rather than a US-reformulated variant, the texture and finish match what Medicube sells through Korean retail.

Key benefits

Built around Melaleuca Alternifolia (Tea Tree) Extract, positioned for clarity.
Built around Ascorbic Acid, positioned for brightening.
Built around 3-O-Ethyl Ascorbic Acid, positioned for brightening.
Formulated as a shampoo for the cleansing step of a hair-care routine.
The Korean-market Medicube formula for Soyxidil Shampoo 490ml, matching what Medicube sells in Korea rather than a US-reformulated line.

How to use

Use this shampoo as the cleansing step of a hair-care routine. To apply, work a coin-sized amount into wet hair and scalp, lather, and rinse thoroughly. Keep it to as often as the scalp needs washing unless the packaging states otherwise, and give the rest of the routine a moment to settle before layering the next step.

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41 of 44 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Sodium C14-16 Olefin Sulfonate surfactant: A strong anionic surfactant that foams heavily. It is a sulfate alternative in name but not in strength, and it is more common in shampoos than in facial cleansers.
Disodium Laureth Sulfosuccinate surfactant: A sulfosuccinate surfactant: milder than a sulfate, with more foam than an amino-acid one. It is often used to soften a sulfate-based cleanser.
Coco-Betaine surfactant: Coco-Betaine is a coconut-derived secondary surfactant used to build foam and make a cleanser milder.
Fragrance (Parfum) fragrance: Fragrance, or Parfum, is a single declaration standing for a whole scent blend, which can be dozens of materials. Regulators allow it as a trade secret, so a list showing only this word does not say what the scent is made of. It is the most common trigger named by people with reactive skin.
Lauryl Hydroxysultaine surfactant: Lauryl Hydroxysultaine is a mild secondary surfactant that keeps foaming even in hard water and at low pH.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Glycine Soja (Soybean) Germ Extract plant extract: Soybean germ extract, from the embryo of the bean. It carries isoflavones and peptides and is used as a conditioning extract.
Oryza Sativa (Rice) Extract plant extract: Rice Extract is the anchor of the Korean rice-skincare category. It carries starches, amino acids and ferulic acid, and it is used for the look of dullness and for a soft, blurred finish.
Sea Salt mineral: Sea Salt is the mineral residue of evaporated seawater: mostly sodium chloride with magnesium, calcium and potassium. It is used as a mild abrasive in scrubs and to adjust how thick a cleanser is.
Aspergillus Ferment ferment: Aspergillus Ferment is a mould ferment, from the same organism family used to make soy sauce and sake. It supplies amino acids and organic acids and is used as a conditioning ferment.
Melaleuca Alternifolia (Tea Tree) Extract plant extract: Tea Tree Leaf Extract is the water-based extract rather than the essential oil, so it is far milder and much less aromatic. It is used in formulas for blemish-prone skin.

29 more explained

Sodium Cocoyl Isethionate surfactant: Sodium Cocoyl Isethionate is a coconut-derived surfactant that gives a dense, creamy foam while staying mild. It is the usual choice in syndet cleansing bars.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Caprylyl Glycol preservative booster: Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
C12-14 Alketh-12 emulsifier: C12-14 Alketh-12 is a solubiliser used to keep oils and fragrance dissolved in a water-based formula.
Sodium Cocoyl Alaninate surfactant: An amino-acid surfactant made from coconut fatty acids and alanine. It foams less aggressively than a sulfate and rinses without the tight feeling.
Sodium Chloride thickener: Sodium Chloride is salt. In a cleanser it thickens the liquid; in a mask or essence it balances the mineral content of the water phase. It has no active role.
Glyceryl Caprylate emulsifier: Glyceryl Caprylate is a mild emulsifier that also makes a formula less hospitable to microbes, so it is often part of a preservative-free system.
Citric Acid pH adjuster: Citric Acid is used in tiny amounts to bring a formula to the pH its actives need, not as an exfoliant at that level. It is an AHA, so at much higher concentrations it can also exfoliate.
Hexylene Glycol solvent: Hexylene Glycol is a solvent and light humectant. It keeps ingredients that resist water in solution and thins a formula so it spreads evenly.
Polyquaternium-10 film former: A cellulose polymer carrying a positive charge. It deposits from a rinse-off formula onto hair or skin and leaves a smooth, anti-static film.
Trihydroxystearin thickener: A castor-derived wax used to thicken oils and stop pigments settling. It builds structure in an anhydrous formula without making it hard.
Caprylic/Capric Triglyceride emollient: Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Sodium Citrate pH adjuster: Sodium Citrate is the salt of citric acid, used as a buffer: it holds a formula at a steady pH rather than pushing it in one direction. It is also a mild chelator.
Diethoxyethyl Succinate solvent: Diethoxyethyl Succinate is a solvent that helps water-resistant actives spread and sink in evenly. It also leaves a light, silky feel.
Sodium Phytate chelator: Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
Pentylene Glycol humectant: Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
Methyl Diisopropyl Propionamide active: A synthetic cooling agent that gives the cool feeling of menthol without the mint smell. It is used where a formula wants the sensation but not the scent.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Tocopherol antioxidant: Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
3-O-Ethyl Ascorbic Acid antioxidant: 3-O-Ethyl Ascorbic Acid is a stable vitamin C derivative that skin converts to ascorbic acid. It survives in a formula far better than pure vitamin C and works at a gentler pH, so it suits skin that finds the pure acid uncomfortable.
Biotin vitamin: Biotin is vitamin B7. In skincare it is a conditioning vitamin, most often in hair and scalp formulas.
Panthenol humectant: Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
Hydroxypropyl Cyclodextrin solvent: Hydroxypropyl Cyclodextrin is a ring-shaped sugar that traps an active molecule inside itself, keeping it stable and releasing it slowly. It is a delivery shell rather than an active.
Methylpropanediol humectant: Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
Copper Tripeptide-1 peptide: Copper Tripeptide-1 is three amino acids bound to a copper ion, and the classic firming peptide in cosmetic chemistry. It is blue in solution, which is often why a serum carrying it is tinted, and it is used for the look of firmness and fine lines.
Octanediol preservative booster: A glycol that hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter.
7-Dehydrocholesterol barrier lipid: 7-Dehydrocholesterol is the sterol skin holds as the precursor to vitamin D. In a formula it behaves as a barrier lipid, closely related to cholesterol.
Cetearyl Alcohol fatty alcohol: Cetearyl Alcohol is a waxy solid, not the drying kind of alcohol. It is a blend of cetyl and stearyl alcohols used to thicken a cream and keep oil and water from separating, and it softens skin as it does so.

Inside the formula

Ingredients declared

Fragrance on the list

Worth knowing

Patch test on the inner arm before the first full-face application, especially on skin that reacts easily to new products.
Stop use and rinse off if stinging, burning, or new redness shows up rather than pushing through discomfort.

Complete the routine

This itemMedicube Soyxidil Shampoo 490ml$47.50
Prep after cleansing, before the treatment stepmedicube Triple Collagen Toner 4.0 140ml$31.00
Seal the routine in as the last stepmedicube Zero Pore Cream 2.0 50ml$30.00

Total for 3 items$108.50

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medicube Soyxidil Shampoo 490ml

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Medicube, Korean-market original

Medicube's Korean-market shampoo led by Melaleuca Alternifolia (Tea Tree) Extract, the same formula sold in Korea.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Medicube prints a QR code on the inner box. Scan it with your phone camera and it resolves to the brand’s own verification site.

Verify on medicubeverify.com →

Source: Medicube packaging and verification site

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about skin care, quoted from the medical sources linked beside each.

Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic
Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic