Centellian24
Madeca Acnience Spot Ampoule 15ml
Centella asiatica extract is first on this 15ml spot ampoule's list, ahead of water, with niacinamide sixth and three tea tree fractions at twelfth through fourteenth, dabbed onto single spots rather than spread.
No reviews yet15ml
$15.99 per 10 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Congested skinUneven textureDry skinCompromised barrier
- Helps with
- Shoppers looking for Niacinamide in an ampouleRoutines that want Niacinamide and Dipotassium Glycyrrhizate in one stepFilling the ampoule step with a Korean-market formula
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- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
Key benefits
- Niacinamide, the active this ampoule is built around
- Dipotassium Glycyrrhizate, Adenosine, Asiaticoside and Madecassic Acid on the same list, actives
- Asiatic Acid and Allantoin further down the same list
- Gluconolactone and Yeast Ferment Extract further down the same list
- Niacinamide named sixth on the manufacturer list printed on this page
Key actives
6Niacinamideactive
Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. On this ampoule's own ingredient list it is named sixth.
46Dipotassium Glycyrrhizateactive
Dipotassium Glycyrrhizate is a water-soluble salt derived from licorice root. It is named forty-sixth on this ampoule's list, alongside Niacinamide.
47Adenosineactive
Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. It is named forty-seventh on this ampoule's list, alongside Niacinamide.
53Asiaticosideactive
Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised. It is named fifty-third on this ampoule's list, alongside Niacinamide.
54Madecassic Acidactive
Madecassic Acid is the fourth centella triterpene. A list that names all four is telling you the extract was standardised rather than simply pressed, which is the difference between a cica claim and a cica formula. The panel names it fifty-fourth on this ampoule's list, beside Niacinamide.
Inside the formula
Inside the formula
- 6Niacinamide
- 46Dipotassium Glycyrrhizate
- 53Asiaticoside
Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.
Centellian24 Madeca Acnience Spot Ampoule 15ml
Where does this ampoule go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than an ampoule goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Niacinamide and not three changes at once.
Does this ampoule contain fragrance?
Yes. The ingredient list names Citronellol, Limonene and Linalool. They sit on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this ampoule is not the one.
What else is on the list besides Niacinamide?
Dipotassium Glycyrrhizate, Adenosine and Asiaticoside. The order they are printed in on this ampoule's panel is the order on the box, so you can see where Niacinamide sits relative to them. Further down the same panel: Madecassic Acid, Asiatic Acid and Allantoin.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (66): Centella Asiatica Extract, Glycerin, Water, Butylene Glycol, 2,3-Butanediol, Niacinamide, Camellia Sinensis Seed Oil, Methylpropanediol, 1,2-Hexanediol, Yeast Ferment Extract, Helianthus Annuus (Sunflower) Seed Oil, Melaleuca Alternifolia (Tea Tree) Extract, Melaleuca Alternifolia (Tea Tree) Flower/Leaf/Stem Extract, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Sodium Hyaluronate, Olea Europaea (Olive) Fruit Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Pelargonium Graveolens Flower Oil, Cryptomeria Japonica Leaf Extract, Nelumbo Nucifera Leaf Extract, Saccharomyces Ferment, Cananga Odorata Flower Oil, Cedrus Atlantica Bark Oil, Lavandula Angustifolia (Lavender) Oil, Rosa Damascena Flower Oil, Citrus Aurantium Dulcis (Orange) Oil, Copaifera Officinalis (Balsam Copaiba) Resin, Jasminum Officinale (Jasmine) Flower Water, Artemisia Absinthium Extract, Citrus Grandis (Grapefruit) Peel Oil, Rose Flower Oil, Ferula Galbaniflua (Galbanum) Resin Oil, Thuja Occidentalis Leaf Oil, Ocimum Sanctum Leaf Extract, Pinus Pinaster Bark Extract, Azadirachta Indica Leaf Extract, Mentha Arvensis Extract, Gaultheria Procumbens (Wintergreen) Leaf Extract, Panthenol, Hydrogenated Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Polyacryloyldimethyl Taurate, Tromethamine, Pentylene Glycol, Dipotassium Glycyrrhizate, Adenosine, Inulin Lauryl Carbamate, Ethylhexylglycerin, Sodium Phytate, Ceteareth-20, Beta-Glucan, Asiaticoside, Madecassic Acid, Asiatic Acid, Tocopherol, Dipropylene Glycol, 4-Terpineol, Gluconolactone, Caprylyl/Capryl Glucoside, Allantoin, Totarol, Ceramide NP, Limonene, Linalool, Citronellol
Ingredient list read from inkeedecoder.com on 18 August 2026.
65 of 66 explained
- Centella Asiatica Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- 2,3-Butanediol humectant
- 2,3-Butanediol is a fermentation-derived glycol. It hydrates and, like the other longer glycols, makes a formula harder for microbes to grow in.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Camellia Sinensis Seed Oil emollient
- Oil pressed from tea seeds. It is high in oleic acid, carries some of the antioxidants of the tea plant, and is lighter in feel than most oleic oils.
- Methylpropanediol humectant
- Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Yeast Ferment Extract ferment
- The extract of a yeast culture, carrying amino acids, sugars and B vitamins. It is used as a conditioning ferment.
- Helianthus Annuus (Sunflower) Seed Oil emollient
- Sunflower Seed Oil is high in linoleic acid, the fatty acid dry and blemish-prone skin is often short of. It is a light, non-fragrant emollient and one of the better tolerated plant oils.
- Melaleuca Alternifolia (Tea Tree) Extract plant extract
- Tea Tree Leaf Extract is the water-based extract rather than the essential oil, so it is far milder and much less aromatic. It is used in formulas for blemish-prone skin.
53 more explained
- Melaleuca Alternifolia (Tea Tree) Flower/Leaf/Stem Extract plant extract
- Tea tree extract taken from the whole plant above ground, rather than the distilled oil. It is much gentler than the oil and is used for the look of congested skin.
- Melaleuca Alternifolia (Tea Tree) Leaf Oil fragrance component
- Tea Tree Leaf Oil is an essential oil from an Australian shrub, carrying terpinen-4-ol. Korean formulas use it in products aimed at blemish-prone skin; it is potent, aromatic, and one of the essential oils most likely to bother reactive skin.
- Candida Bombicola/Glucose/Methyl Rapeseedate Ferment ferment
- This ferment produces sophorolipids, sugar-based molecules that behave as very mild surfactants and emulsifiers. It is used to keep a formula blended without a harsh cleanser.
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- Olea Europaea (Olive) Fruit Oil emollient
- Olive Fruit Oil is high in oleic acid and plant sterols. It is a rich emollient that suits dry skin and is heavy enough that blemish-prone skin often does not get on with it.
- Citrus Aurantium Bergamia (Bergamot) Fruit Oil fragrance component
- Bergamot Fruit Oil is a citrus essential oil and the top note of eau de cologne. It scents a formula; citrus oils are the aromatic class most likely to bother reactive skin.
- Pelargonium Graveolens Flower Oil fragrance component
- Pelargonium Graveolens is rose geranium. Its flower oil is an essential oil used to scent a formula, carrying citronellol and geraniol.
- Cryptomeria Japonica Leaf Extract plant extract
- Cryptomeria Japonica is Japanese cedar. Its leaf extract is used as an aromatic antioxidant plant extract.
- Nelumbo Nucifera Leaf Extract plant extract
- Nelumbo Nucifera is the sacred lotus. Its leaf extract carries flavonoids and is used as a conditioning antioxidant extract.
- Saccharomyces Ferment ferment
- Saccharomyces Ferment is a brewer's yeast ferment. It supplies amino acids, sugars and B vitamins and is used as a conditioning, hydrating ferment.
- Cananga Odorata Flower Oil fragrance
- Ylang ylang oil, a heavy sweet floral essential oil. It is among the most commonly declared natural fragrance materials.
- Cedrus Atlantica Bark Oil fragrance component
- Atlas Cedar Bark Oil is a woody essential oil used to scent a formula.
- Lavandula Angustifolia (Lavender) Oil fragrance component
- Lavender Oil is an essential oil carrying linalool and linalyl acetate. It scents a formula, and linalool is one of the fragrance components EU labelling requires to be named separately.
- Rosa Damascena Flower Oil fragrance component
- Rosa Damascena Flower Oil is rose essential oil, one of the most expensive materials in perfumery. It scents a formula, and like every essential oil it is a class reactive skin often does not tolerate.
- Citrus Aurantium Dulcis (Orange) Oil fragrance component
- Sweet Orange Peel Oil is a citrus essential oil carrying limonene. It scents a formula, and limonene is one of the components EU labelling names separately.
- Copaifera Officinalis (Balsam Copaiba) Resin emollient
- Copaiba Resin is a fragrant tree resin used as a thick emollient and a natural scent component in balms.
- Jasminum Officinale (Jasmine) Flower Water plant extract
- Jasmine distillate, used in place of plain water as a base. A flower water is far more dilute than the oil, so it sets the base and carries a faint scent.
- Artemisia Absinthium Extract plant extract
- Artemisia Absinthium is wormwood, another mugwort relative. Its extract carries aromatic plant compounds and is used as a conditioning extract.
- Citrus Grandis (Grapefruit) Peel Oil fragrance component
- Grapefruit Peel Oil is a citrus essential oil rich in limonene. It scents a formula and belongs to the aromatic class reactive skin often avoids.
- Ferula Galbaniflua (Galbanum) Resin Oil fragrance component
- Galbanum Resin Oil is a green, resinous essential oil used in perfumery to scent a formula.
- Thuja Occidentalis Leaf Oil fragrance
- Northern white cedar leaf oil, a sharp coniferous essential oil used at very low levels for scent.
- Ocimum Sanctum Leaf Extract plant extract
- Ocimum Sanctum is holy basil, or tulsi. Its leaf extract carries plant antioxidants and is used in formulas built for the look of stressed, reactive skin.
- Pinus Pinaster Bark Extract plant extract
- Maritime pine bark extract, the source of the proanthocyanidins sold under the pine bark name. It is used as a plant antioxidant.
- Azadirachta Indica Leaf Extract plant extract
- Melia Azadirachta is neem. Its leaf and flower extracts are long-standing Ayurvedic ingredients, and Korean formulas use them in products aimed at the look of congested, blemish-prone skin.
- Mentha Arvensis Extract plant extract
- Field mint leaf extract, the plant most menthol is distilled from. The extract is far gentler than the oil and carries a light cooling character.
- Gaultheria Procumbens (Wintergreen) Leaf Extract plant extract
- Wintergreen leaf extract. The plant naturally carries methyl salicylate, which is where its sharp minty scent comes from.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener
- This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
- Sodium Polyacryloyldimethyl Taurate thickener
- Sodium Polyacryloyldimethyl Taurate is a polymer thickener that holds a gel stable even with a lot of salt or acid in the formula.
- Tromethamine pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
- Pentylene Glycol humectant
- Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
- Dipotassium Glycyrrhizate active
- Dipotassium Glycyrrhizate is a water-soluble salt derived from licorice root. It is the licorice fraction Korean formulas use for the look of redness, and it is far more stable in water than the whole extract.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Inulin Lauryl Carbamate emulsifier
- A chicory-sugar polymer with a fatty chain attached. It stabilises an emulsion by forming a film at the oil and water boundary rather than acting as a classic surfactant.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Sodium Phytate chelator
- Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
- Ceteareth-20 emulsifier
- An ethoxylated fatty alcohol that holds oil and water together in a cream. The number records how much ethylene oxide was added, which sets how water-loving it is.
- Beta-Glucan polysaccharide
- Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
- Asiaticoside active
- Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised.
- Madecassic Acid active
- Madecassic Acid is the fourth centella triterpene. A list that names all four is telling you the extract was standardised rather than simply pressed, which is the difference between a cica claim and a cica formula.
- Asiatic Acid active
- Asiatic Acid is the third of centella's four triterpenes and the aglycone form, meaning it has no attached sugar. It is oil soluble, so it turns up in cica creams and balms more than in watery layers.
- Tocopherol antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- 4-Terpineol fragrance component
- A terpene alcohol, and the main constituent of tea tree oil. On a label it is an aromatic plant constituent rather than a functional ingredient.
- Gluconolactone exfoliant
- Gluconolactone is a PHA, the gentlest exfoliant class. Its molecule is too large to penetrate quickly, so it smooths the surface without the sting of an AHA, and it is a humectant at the same time.
- Caprylyl/Capryl Glucoside surfactant
- Caprylyl/Capryl Glucoside is a sugar-derived cleansing surfactant. It foams modestly and is mild enough for low-pH cleansers built for reactive skin.
- Allantoin active
- Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin.
- Totarol preservative booster
- A compound from the heartwood of the New Zealand totara tree. It is antimicrobial, so a formula uses it to support the preservative system.
- Ceramide NP barrier lipid
- Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
- Limonene fragrance component
- Limonene is the citrus-peel aromatic. It appears here because EU labelling requires 26 fragrance components to be named individually rather than hidden inside "fragrance", and it is one of them.
- Linalool fragrance component
- Linalool is a floral aromatic found in lavender, bergamot and coriander. It is one of the 26 fragrance components EU labelling requires to be declared by name.
- Citronellol fragrance component
- Citronellol is a rose-geranium aromatic and one of the 26 fragrance components EU labelling names individually.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8806109100649
- Made in
- Republic of Korea
- Volume
- 15ml
- Category
- Serum & Ampoule
- Actives
- Adenosine, Allantoin, Beta-Glucan, Centella Asiatica, Ceramide NP, Green Tea, Licorice Root, Niacinamide, Panthenol, Sodium Hyaluronate, Tea Tree
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How it works
The Madeca Acnience Spot Ampoule is a 15ml ampoule, used after toner and before moisturizer, morning and evening. The active it is built around is Niacinamide, named sixth on its own ingredient list. The same list carries Dipotassium Glycyrrhizate, Adenosine and Asiaticoside, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the ampoule format rather than by the list alone. Centellian24 sells this Niacinamide ampoule in Korea, and this is that version.
How to use
- Use it in the evening after toner, on the congested areas or across the whole face.
- A drop pressed onto each area; it is thin enough to spread over the face if you prefer.
- Let it settle before your moisturizer goes over the top of it.
- Every evening. Keep it off broken skin, and do not stack it with a scrub in the same routine.
Worth knowing
- Patch test this ampoule on a small area and wait a day before using it more widely, especially with Niacinamide on the list.
- This list names Citronellol, Limonene and Linalool, so skip it if fragrance components are something you avoid.
- Gluconolactone on this list makes this ampoule an exfoliating step, so do not stack it with another one on the same night.
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Centellian24 Madeca Acnience Spot Ampoule 15ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
Creators trying on authentic Korean skincare routines and products from us.
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Centellian24, Korean-market original
Cica spot ampoule, 15 ml, with Centella Asiatica first, Niacinamide and Tea Tree.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.
It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin.
Jennifer Chwalek, MDDermatologist, Byrdie Centella can make your skin appear more hydrated, plumper and healthier.
Samantha Stein, PA-CDermatology physician assistant, Cleveland Clinic
1 more professional perspective
Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.
Ashlyn YankeAesthetician, Cleveland Clinic
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