Medicube
SOS Invisible Patch 36ea$25.00BioSIS 360 Micropyramid Patch 3ea
Eleven ingredients, sodium hyaluronate first: three dissolving micropyramid patches carrying acetyl myricetin, myricetin and madecassoside into one spot overnight. Original Korean Formula.
No reviews yet3 ea
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Congested skinUneven textureDehydrated skin
- Helps with
- Shoppers looking for Madecassoside in a patchRoutines that want Madecassoside and Adenosine in one stepFilling the patch step with a Korean-market formulaAnyone who wants the Madecassoside patch sold on Korean shelves
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The BioSIS 360 Micropyramid Patch is a 3ea patch, used apply a patch from it to clean, dry skin at the end of the evening routine. The active it is built around is Madecassoside, named seventh on its own ingredient list. The same list carries Adenosine, Arginine and Sodium Hyaluronate, so the active is not the only thing on it worth naming. How much of the Madecassoside stays on the skin, and for how long, is decided by the patch format rather than by the list alone. This is the Original Korean Formula, the patch Huxley sells in Korea, Madecassoside and all.
Key benefits
- Madecassoside, the active this patch is built around
- Adenosine on the same list, an active
- Arginine on the same list, an amino acid
- Sodium Hyaluronate and Trehalose on the same list, humectants
- Madecassoside named seventh on the manufacturer list printed on this page
- Sourced for the Korean market, not a US-shelf reformulation of this patch
How to use
- Use it as the routine step, AM and PM, worked into the wider routine, giving it a moment to settle before the next step.
Where does this patch go in my routine?
Apply a patch from it to clean, dry skin at the end of the evening routine. Toner goes on before it, and the rest of the routine goes on after you take the patch off. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Madecassoside and not three changes at once.
Is this the Korean-market patch or a US version?
The Korean-market one, Madecassoside and all. We match this patch to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Madecassoside?
Adenosine, Arginine and Sodium Hyaluronate. The order they are printed in on this patch's panel is the order on the box, so you can see where Madecassoside sits relative to them. Further down the same panel: Trehalose.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (11): Sodium Hyaluronate, Trehalose, Glycerin, Citric Acid, Acetyl Myricetin, Myricetin, Madecassoside, Sodium Citrate, Arginine/Lysine Polypeptide, Polyglyceryl-10 Laurate, Adenosine
Ingredient list read from en.huxley.co.kr on 30 August 2026.
9 of 11 explained
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- Trehalose humectant
- Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Citric Acid pH adjuster
- Citric Acid is used in tiny amounts to bring a formula to the pH its actives need, not as an exfoliant at that level. It is an AHA, so at much higher concentrations it can also exfoliate.
- Madecassoside active
- Madecassoside is the centella triterpene most associated with the look of redness, and the one brands lead with in cica products. It is water soluble and stable, so it appears in essences as readily as in creams.
- Sodium Citrate pH adjuster
- Sodium Citrate is the salt of citric acid, used as a buffer: it holds a formula at a steady pH rather than pushing it in one direction. It is also a mild chelator.
- Arginine/Lysine Polypeptide peptide
- A polypeptide built from the amino acids arginine and lysine. It holds water strongly and leaves a smoothing film.
- Polyglyceryl-10 Laurate emulsifier
- Polyglyceryl-10 Laurate is a sugar-derived emulsifier and solubiliser, mild enough to be a standard choice in Korean essences. It dissolves small amounts of oil into water without any tightening feel.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809422539127
- Made in
- Republic of Korea
- Volume
- 3 ea
- Category
- Patch
- Actives
- Adenosine, Centella Asiatica, Madecassoside, Sodium Hyaluronate, Trehalose
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
Inside the formula
Inside the formula
Worth knowing
- Patch test this patch on a small area and wait a day before using it more widely, especially with Madecassoside on the list.
- Introduce this patch on its own for the first week, so anything your skin does is traceable to the Madecassoside rather than to three changes at once.
Complete the routine
- This itemHuxley BioSIS 360 Micropyramid Patch 3ea$47.50

- Cleanse first, so the next step meets bare skinHuxley Cleansing Gel ; Be Clean, Be Moist 200ml$47.50

- Prep after cleansing, before the treatment stepHuxley Toner ; Extract It 120ml$47.50

Total for 3 items$142.50
Reviews
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Huxley BioSIS 360 Micropyramid Patch 3ea
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
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A first try of the Dr. Althea serum on camera.
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Huxley, Korean-market original
The Original Korean Formula patch from Huxley, 3ea formulated with Madecassoside and Adenosine, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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