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Free US shipping on orders of $100 or more. 100% authentic Korean-market formulas. Ships from our California warehouse, at your door in 3-5 days. Intact Korean batch codes on every unit.

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KOREAN PHARMACY

IOPE Bio Conditioning Essence 168ml

IOPE Bio Conditioning Essence is IOPE's 168ml essence, formulated with Niacinamide.

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$70.00
  • Ships from our California warehouse
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Suited to
Normal skinDry skinCombination skin
Helps with
Layering a concentrated, targeted step into an existing routineShoppers who want IOPE's own Korean-market formula rather than a US-shelf version

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Key benefits

  • Niacinamide, the active this essence is built around
  • Adenosine on the same list, an active
  • Acetyl Heptapeptide-4 and Acetyl Octapeptide-3 on the same list, peptides
  • Saccharomyces Ferment Filtrate on the same list, a ferment
  • Saccharomyces Cerevisiae Extract further down the same list
  • Niacinamide named fifth on the manufacturer list printed on this page

Key actives

Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. On this essence's own ingredient list it is named fifth.

Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. It is named eleventh on this essence's list, alongside Niacinamide.

Acetyl Heptapeptide-4peptide

A seven-amino-acid peptide with an acetyl group added for stability. It is used as a conditioning peptide for the look of firmness. The panel names it sixteenth on this essence's list, beside Niacinamide.

Acetyl Octapeptide-3peptide

Acetyl Octapeptide-3 is an eight-amino-acid peptide used for the look of expression lines. It is usually paired with acetyl hexapeptide-8 rather than used alone. The panel names it nineteenth on this essence's list, beside Niacinamide.

Saccharomyces Ferment Filtrateferment

Saccharomyces Ferment Filtrate is a brewers yeast ferment filtered clear. It supplies amino acids, B vitamins and sugars, and it is one of the ferments the Korean essence category was built on. The panel names it first on this essence's list, beside Niacinamide.

How to use

  1. After toner, before a heavier serum.
  2. Pat a few drops over the face and neck.
  3. Follow with serum or moisturizer.

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IOPE Bio Conditioning Essence 168ml

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How it works

The Bio Conditioning Essence is a 168ml essence, used after toner and before serum, morning and evening, on damp skin. The active it is built around is Niacinamide, named fifth on its own ingredient list. The same list carries Adenosine, Acetyl Heptapeptide-4 and Acetyl Octapeptide-3, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the essence format rather than by the list alone. This is the Original Korean Formula, the essence IOPE sells in Korea, Niacinamide and all.

Worth knowing

  • Patch test on a small area first and wait a day before full use, especially the first time.

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We’re on gram!

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Korean-market original

The Original Korean Formula essence from IOPE, 168ml formulated with Niacinamide and Adenosine, held in the United States and shipped domestically.

Verify your unit when it arrives

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Match the batch code on the box against the code printed on the bottle or tube itself; the two are stamped separately and should agree.

On the unit itself

  • The Korean-market barcode, unaltered from the retail package.
  • The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

  • Peptides can be anti-inflammatory, and chronic inflammation damages the tissue in your skin.

    Wilma Bergfeld, MDDermatologist, Cleveland Clinic
  • In skin, different peptides can encourage different things, from collagen formation to a reduction in inflammation to helping with wound healing depending on their structure.

    Whitney Hovenic, MDDouble board-certified dermatologist and Mohs surgeon, Women's Health
1 more professional perspective
  • Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.

    Ashlyn YankeAesthetician, Cleveland Clinic

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