VT Cosmetics
VT Vita-Light Reedle Shot 300 50ml$67.50Bio Conditioning Essence 168ml
IOPE Bio Conditioning Essence is IOPE's 168ml essence, formulated with Niacinamide.
No reviews yet168 ml
$41.67 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Normal skinDry skinCombination skin
- Helps with
- Layering a concentrated, targeted step into an existing routineShoppers who want IOPE's own Korean-market formula rather than a US-shelf version
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The Bio Conditioning Essence is a 168ml essence, used after toner and before serum, morning and evening, on damp skin. The active it is built around is Niacinamide, named fifth on its own ingredient list. The same list carries Adenosine, Acetyl Heptapeptide-4 and Acetyl Octapeptide-3, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the essence format rather than by the list alone. This is the Original Korean Formula, the essence IOPE sells in Korea, Niacinamide and all.
Key benefits
- Niacinamide, the active this essence is built around
- Adenosine on the same list, an active
- Acetyl Heptapeptide-4 and Acetyl Octapeptide-3 on the same list, peptides
- Saccharomyces Ferment Filtrate on the same list, a ferment
- Saccharomyces Cerevisiae Extract further down the same list
- Niacinamide named fifth on the manufacturer list printed on this page
Inside the formula
Inside the formula
Where does this essence go in my routine?
After toner and before serum, morning and evening, on damp skin. Anything thinner than an essence goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Niacinamide and not three changes at once.
Is this the Korean-market essence or a US version?
The Korean-market one, Niacinamide and all. We match this essence to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Niacinamide?
Adenosine, Acetyl Heptapeptide-4 and Acetyl Octapeptide-3. The order they are printed in on this essence's panel is the order on the box, so you can see where Niacinamide sits relative to them. Further down the same panel: Saccharomyces Ferment Filtrate and Saccharomyces Cerevisiae Extract.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (19): Saccharomyces Ferment Filtrate, Butylene Glycol, Propanediol, Glycerol, Nicotinamide, 1,2-Hexanediol, Diethoxyethyl Succinate, Aqua, Sodium Pyruvate, Ethylhexylglycerin, Adenosine, Dextrin, Edetate Disodium, Saccharomyces Cerevisiae Extract, Caprylyl Glycol, Acetyl Heptapeptide-4, Acetyl Hexapeptide-3, Sodium Hydroxide, Acetyl Octapeptide-3
Ingredient list read from inkeedecoder.com on 10 September 2026.
16 of 19 explained
- Saccharomyces Ferment Filtrate ferment
- Saccharomyces Ferment Filtrate is a brewers yeast ferment filtered clear. It supplies amino acids, B vitamins and sugars, and it is one of the ferments the Korean essence category was built on.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- Propanediol humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- Glycerol humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Nicotinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Diethoxyethyl Succinate solvent
- Diethoxyethyl Succinate is a solvent that helps water-resistant actives spread and sink in evenly. It also leaves a light, silky feel.
- Aqua solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Dextrin thickener
- Dextrin is a starch fragment used to thicken and to give a formula a light, powdery finish. It is also a common carrier for powdered extracts.
- Saccharomyces Cerevisiae Extract ferment
- An extract of brewer's yeast, the same organism used to make bread and beer. It supplies amino acids, sugars and beta-glucan and is used as a conditioning ferment.
4 more explained
- Caprylyl Glycol preservative booster
- Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
- Acetyl Heptapeptide-4 peptide
- A seven-amino-acid peptide with an acetyl group added for stability. It is used as a conditioning peptide for the look of firmness.
- Sodium Hydroxide pH adjuster
- Sodium Hydroxide is a strong base used in traces to bring an acidic formula up to skin-friendly pH. None of it remains as itself once the formula is neutralised.
- Acetyl Octapeptide-3 peptide
- Acetyl Octapeptide-3 is an eight-amino-acid peptide used for the look of expression lines. It is usually paired with acetyl hexapeptide-8 rather than used alone.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809803563239
- Made in
- Republic of Korea
- Volume
- 168 ml
- Category
- Essence
- Actives
- Adenosine, Peptides
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- After toner, before a heavier serum.
- Pat a few drops over the face and neck.
- Follow with serum or moisturizer.
Worth knowing
- Patch test on a small area first and wait a day before full use, especially the first time.
Complete the routine
- This itemIOPE Bio Conditioning Essence 168ml$70.00

- Seal the routine in as the last stepIOPE SUPER VITAL EMULSION 150ml$87.50

- The treatment step of this routineIOPE RETINOL RETI-JECTION SERUM 30ml$100.00

Total for 3 items$257.50
Reviews
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IOPE Bio Conditioning Essence 168ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
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A first try of the Dr. Althea serum on camera.
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IOPE, Korean-market original
The Original Korean Formula essence from IOPE, 168ml formulated with Niacinamide and Adenosine, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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