Cica Double Effect Ampoule 30ml
Squalane fourth and arbutin fifth lead this 30 ml isoi ampoule, with sericin, the silk protein, seventh, then cnidium, mistletoe and hinoki cypress leaf extracts, and centella thirteenth. Korean-market formula.
No reviews yet30 ml
$150.00 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Sensitive skinDry skinNormal skin
- Helps with
- Skin that looks stressed, dry, or easily irritatedFitting a Korean-market step into an existing routineShoppers who want the same formula sold on shelves in Korea
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The Cica Double Effect Ampoule is a 30ml ampoule, used after toner and before moisturizer, morning and evening. The plant extract it is built around is Centella Asiatica Extract, named thirteenth on its own ingredient list. The same list carries Arbutin, Chamaecyparis Obtusa Leaf Extract and Scutellaria Baicalensis Root Extract, so the plant extract is not the only thing on it worth naming. How much of the Centella Asiatica Extract stays on the skin, and for how long, is decided by the ampoule format rather than by the list alone. This is the Original Korean Formula, the ampoule isoi sells in Korea, Centella Asiatica Extract and all.
Key benefits
- Centella Asiatica Extract, the plant extract this ampoule is built around
- Arbutin on the same list, an active
- Chamaecyparis Obtusa Leaf Extract, Scutellaria Baicalensis Root Extract and Paeonia Suffruticosa Root Extract on the same list, plant extracts
- Glycyrrhiza Glabra (Licorice) Root Extract and Castanea Crenata (Chestnut) Shell Extract further down the same list
- Salix Alba (Willow) Bark Extract and Melia Azadirachta Leaf Extract further down the same list
- Centella Asiatica Extract named thirteenth on the manufacturer list printed on this page
How to use
- Apply morning and night after toner or essence and before moisturizer, pressing a small amount into the skin and letting it absorb fully before the next step.
Where does this ampoule go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than an ampoule goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Centella Asiatica Extract and not three changes at once.
Is this the Korean-market ampoule or a US version?
The Korean-market one, Centella Asiatica Extract and all. We match this ampoule to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Centella Asiatica Extract?
Arbutin, Chamaecyparis Obtusa Leaf Extract and Scutellaria Baicalensis Root Extract. The order they are printed in on this ampoule's panel is the order on the box, so you can see where Centella Asiatica Extract sits relative to them. Further down the same panel: Paeonia Suffruticosa Root Extract, Glycyrrhiza Glabra (Licorice) Root Extract and Castanea Crenata (Chestnut) Shell Extract.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (23): Water, Glycerin, Cetyl Ethylhexanoate, Squalane, Arbutin, Sodium Chloride, Sericin, Cnidium Monnieri Fruit Extract, Viscum Album (Mistletoe) Extract, Chamaecyparis Obtusa Leaf Extract, Macadamia Ternifolia Seed Oil, Panthenol, Centella Asiatica Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Xanthan Gum, Sorbitan Sesquioleate, Castanea Crenata (Chestnut) Shell Extract, Salix Alba (Willow) Bark Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract
Ingredient list read from inkeedecoder.com on 10 September 2026.
19 of 23 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Cetyl Ethylhexanoate emollient
- Cetyl Ethylhexanoate is a synthetic ester used as a dry-feeling emollient. It spreads easily, leaves a silky rather than oily finish, and helps disperse pigments and UV filters evenly.
- Squalane emollient
- Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
- Arbutin active
- Arbutin is the naturally occurring form of the same compound, from bearberry and related plants, used for the look of uneven tone. The alpha isomer is the more stable of the two.
- Sodium Chloride thickener
- Sodium Chloride is salt. In a cleanser it thickens the liquid; in a mask or essence it balances the mineral content of the water phase. It has no active role.
- Chamaecyparis Obtusa Leaf Extract plant extract
- Chamaecyparis Obtusa is hinoki cypress. Its leaf extract carries aromatic plant compounds and is used in Korean formulas aimed at oily, congested skin.
- Macadamia Ternifolia Seed Oil emollient
- Macadamia Seed Oil is unusually high in palmitoleic acid, a fatty acid that human sebum also contains, which is why it absorbs faster than most nut oils. It is a cushioning emollient for dry skin.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Centella Asiatica Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Citrus Aurantium Bergamia (Bergamot) Fruit Oil fragrance component
- Bergamot Fruit Oil is a citrus essential oil and the top note of eau de cologne. It scents a formula; citrus oils are the aromatic class most likely to bother reactive skin.
- Scutellaria Baicalensis Root Extract plant extract
- Scutellaria Baicalensis is Chinese skullcap. Its root extract carries baicalin, a well studied plant antioxidant, and it is used for the look of redness.
7 more explained
- Paeonia Suffruticosa Root Extract plant extract
- Paeonia Suffruticosa is tree peony, a long-standing East Asian medicinal plant. Its root extract carries paeoniflorin and is used for the look of reddened skin.
- Glycyrrhiza Uralensis (Licorice) Root Extract plant extract
- Licorice Root Extract carries glabridin and liquiritin. It is one of the classic plant ingredients used for the look of uneven tone and redness, and it appears in almost every brightening formula that avoids synthetic actives.
- Xanthan Gum thickener
- Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
- Sorbitan Sesquioleate emulsifier
- Sorbitan Sesquioleate is a water-in-oil emulsifier and pigment disperser. Cleansing oils use it so water can be worked into the oil at the rinse.
- Castanea Crenata (Chestnut) Shell Extract plant extract
- Chestnut Shell Extract carries tannins and is used as an antioxidant plant extract, most often in formulas aimed at visible pores.
- Salix Alba (Willow) Bark Extract plant extract
- Willow Bark Extract carries salicin, the plant compound salicylic acid is related to. The two are not interchangeable: willow bark is a mild clarifying extract, not a BHA exfoliant at the levels used in cosmetics.
- Melia Azadirachta Leaf Extract plant extract
- Melia Azadirachta is neem. Its leaf and flower extracts are long-standing Ayurvedic ingredients, and Korean formulas use them in products aimed at the look of congested, blemish-prone skin.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809317282992
- Made in
- Republic of Korea
- Volume
- 30 ml
- Category
- Serum & Ampoule
- Actives
- Arbutin, Centella Asiatica, Licorice Root, Panthenol, Squalane
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
Inside the formula
Inside the formula
Worth knowing
- Introduce any new product gradually rather than adding several new steps to a routine at once, so a reaction is easy to trace back to the right cause.
- Patch test on a small area first and wait a day before applying it to the full face, especially the first time you use it.
Complete the routine
- This itemisoi Cica Double Effect Ampoule 30ml$45.00

- The treatment step of this routineisoi Bulgarian Rose Blemish Care Spot 25ml$45.00

- Seal the routine in as the last stepisoi Bulgarian Rose Intensive Treatment Lotion 90ml$95.00

Total for 3 items$185.00
Reviews
No reviews yet. Tell us how much you love the product!
Write a reviewWrite a review
isoi Cica Double Effect Ampoule 30ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
Creators trying on authentic Korean skincare routines and products from us.
Rating a shelf of Dr. Althea products one by one.
Jasmine Loo · YouTube
Two hydrating serums side by side, IUNIK and Dr. Althea.
Kristin · YouTube
A walk through the Dr. Althea serum lineup and who each one suits.
auraofmahmuda · YouTube
A blunt first take on the Dr. Althea range.
Lexi Chang · YouTube
A first look at the viral 345 Relief Cream before buying.
Shelley Nayak · YouTube
A first try of the Dr. Althea serum on camera.
Hannah Ziad · YouTube
isoi, Korean-market original
The Original Korean Formula ampoule from isoi, 30ml formulated with Centella Asiatica Extract and Arbutin, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
Ask an AI assistant about this product
Ask an AI assistant about this product
Opens ChatGPT, Perplexity or Claude in a new tab with the question prefilled. Claude asks you to sign in first.






