Manyo Factory
Bifida Biome Concentrate Serum 35ml
Manyo Factory Bifida Biome Concentrate Serum 35ml is a serum led by Bifida Ferment Lysate on its own ingredient panel, sourced as the Korean-market formula.
No reviews yet35 ml
$107.14 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- normalcombinationdryoily
- Helps with
- tone and texture supported by Bifida Ferment Lysatedaily hydration through the serum stepa Korean-market formula rather than a US reformulationa routine step matched to this format
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
Bifida Ferment Lysate leads the ingredient panel on this serum. Bifida Ferment Lysate is a bifidobacteria ferment with the cells broken open. It is the ingredient behind the first-essence category and is used for the look of tired, reactive skin. On this panel it sits alongside Niacinamide, Rosa Damascena Flower Water and Phytosphingosine. Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
Key benefits
- Bifida Ferment Lysate named on this product's own ingredient panel, near the top of it
- Niacinamide on the same panel, the formula's active
- Rosa Damascena Flower Water on the same panel, the formula's plant extract
- 35 ml to a unit
- Korean GS1 barcode matched against a Korea sourcing supplier's record for this item
How to use
- Use it as the serum step, AM and PM, after toner and before moisturizer, giving it a moment to settle before the next step.
How do I know this is authentic and not a US-reformulated version?
Check the box against the listing: an authentic Korean-market SKU carries Korean-primary packaging and an intact Korean-market batch code, not a US-only relabel. Manyo Factory's Korean-market formulas are sourced specifically to preserve that, rather than substituted for the US-shelf version some retailers carry under the same name.
When in a routine should I use this serum?
Use it as the serum step, AM and PM, after toner and before moisturizer. Placing a serum out of order is the most common reason a Korean routine feels like it is not working, so keep this one at its own step rather than doubling it up with a product built for a different stage. Give it a few weeks at that placement before judging the result.
Is this the same formula sold in Korea, or a US version?
This is the authentic Korean-market version of the formula, not a US-shelf substitute. Manyo Factory sells a separate reformulation on some US shelves, and this listing is not that version. The Korean-market batch coding and packaging travel with it, which is the detail worth checking against the box on arrival.
What does Bifida Ferment Lysate do in this formula?
Bifida Ferment Lysate is a fermented ingredient Korean formulas use to condition the surface with a lighter feel than many actives. Fermented ingredients like this are a defining thread of Korean formulation, chosen for a gentler daily-use feel. It sits at its own position on this product's own ingredient list rather than being assumed from the product name.
Not on the ingredient list below: denatured or SD alcohol, essential oils, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (50): Bifida Ferment Lysate (51%), Glycerin, Dipropylene Glycol, Propanediol, 1,2-Hexanediol, Water, Butylene Glycol, Niacinamide, Rosa Damascena Flower Water, Panthenol, Cutibacterium Granulosum Ferment Extract Filtrate (10,000Ppm), Phytosphingosine, Acetylphytosphingosine, Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Sodium Acrylates Copolymer, Caprylic/Capric Triglyceride, Glyceryl Acrylate/Acrylic Acid Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Adenosine, Squalane, Polyglyceryl-10 Laurate, Polyglyceryl-10 Myristate, Ceramide NP, Ceramide NS, Ceramide AP, Ceramide EOP, Cholesterol, Centella Asiatica Leaf Water, Camellia Sinensis Leaf Extract, Olea Europaea (Olive) Fruit Oil, Butyrospermum Parkii (Shea) Butter, Hydrogenated Lecithin, Polyglyceryl-4 Oleate, Ethylhexyl Olivate, Ethylhexylglycerin, Disodium EDTA, Arginine, Carbomer, Portulaca Oleracea Extract, Linalool, Citronellol, Benzyl Salicylate, Parfum (Fragrance)
Ingredient list read from inkeedecoder.com on 10 September 2026.
47 of 50 explained
- Bifida Ferment Lysate (51%) ferment
- Bifida Ferment Lysate is a bifidobacteria ferment with the cells broken open. It is the ingredient behind the first-essence category and is used for the look of tired, reactive skin.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- Propanediol humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Rosa Damascena Flower Water plant extract
- Rosa Damascena Flower Water is the water left from distilling rose petals. It is used in place of plain water as a base and carries the scent and trace compounds of the distillation.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Phytosphingosine barrier lipid
- Phytosphingosine is the backbone every ceramide is built on, and skin uses it in its own lipid layer. In a formula it works with ceramides and cholesterol and also keeps the product stable against microbes.
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
35 more explained
- Hydroxypropyltrimonium Hyaluronate humectant
- Hydroxypropyltrimonium Hyaluronate carries a positive charge, and skin carries a slight negative one, so it is attracted to the surface and stays through rinsing. It is the hyaluronic used where a formula gets washed off.
- Hydrolyzed Hyaluronic Acid humectant
- Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
- Sodium Acetylated Hyaluronate humectant
- Sodium Acetylated Hyaluronate is hyaluronic acid modified to be part oil-loving, so it clings to skin instead of rinsing away. Formulators call it the one that stays put.
- Sodium Hyaluronate Crosspolymer humectant
- Sodium Hyaluronate Crosspolymer is hyaluronic acid linked into a mesh. It holds water in a soft gel on the surface rather than sinking in, and it releases that water slowly through the day.
- Hyaluronic Acid humectant
- Hyaluronic Acid is a sugar chain the body already makes, and one gram of it can hold several litres of water. In a formula it is a humectant that pulls water to the surface of skin and holds it in a film, which is what makes skin look plumper while it is there.
- Potassium Hyaluronate humectant
- Potassium Hyaluronate is another salt of hyaluronic acid, used for the same reason as the sodium form: it dissolves easily and holds a large amount of water in the outer layer of skin.
- Sodium Acrylates Copolymer thickener
- An acrylate polymer that thickens water and can hold many times its own weight in it. It gives a gel body without any oil.
- Caprylic/Capric Triglyceride emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- Glyceryl Acrylate/Acrylic Acid Copolymer film former
- This is a polymer that forms a moisture-holding film on the surface, usually supplied with glycerin and propylene glycol as a hydrating complex.
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener
- This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Squalane emollient
- Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
- Polyglyceryl-10 Laurate emulsifier
- Polyglyceryl-10 Laurate is a sugar-derived emulsifier and solubiliser, mild enough to be a standard choice in Korean essences. It dissolves small amounts of oil into water without any tightening feel.
- Polyglyceryl-10 Myristate emulsifier
- Polyglyceryl-10 Myristate is a mild sugar-derived emulsifier used to keep oil dispersed in a watery formula.
- Ceramide NP barrier lipid
- Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
- Ceramide NS barrier lipid
- Ceramide NS is another of the ceramides skin makes for itself. It is used alongside NP and AP so a formula supplies a mixture rather than a single lipid.
- Ceramide AP barrier lipid
- Ceramide AP is a second cosmetic ceramide, distinguished by an extra hydroxyl group. Formulas that name several ceramides are copying the mix skin actually holds rather than relying on one.
- Ceramide EOP barrier lipid
- Ceramide EOP is the ceramide with the longest tail, and in skin it acts as the rivet holding the lipid layers together. It is the third member of the standard cosmetic ceramide trio.
- Cholesterol barrier lipid
- Cholesterol is the third of the three lipids the outer layer of skin is built from, with ceramides and fatty acids. Formulas that carry all three are following the ratio skin itself holds.
- Centella Asiatica Leaf Water plant extract
- Centella Asiatica Leaf Water is the distilled water of the centella leaf, used in place of plain water as a formula base. It is far more dilute than the extract, so it sets the base rather than supplying the actives.
- Camellia Sinensis Leaf Extract plant extract
- Camellia Sinensis is the tea plant. Green tea leaf extract carries catechins, among the most studied plant antioxidants, and is used for the look of redness and oily shine.
- Olea Europaea (Olive) Fruit Oil emollient
- Olive Fruit Oil is high in oleic acid and plant sterols. It is a rich emollient that suits dry skin and is heavy enough that blemish-prone skin often does not get on with it.
- Butyrospermum Parkii (Shea) Butter emollient
- Shea Butter is the fat pressed from the shea nut, rich in oleic and stearic acids and unsaponifiable plant sterols. It is a heavy emollient and partial occlusive, which is why it sits in balms and night creams rather than in essences.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Polyglyceryl-4 Oleate emulsifier
- Polyglyceryl-4 Oleate is a plant-derived emulsifier used in cleansing oils so they rinse cleanly.
- Ethylhexyl Olivate emollient
- An ester built from olive oil fatty acids. It gives the softening feel of a plant oil with a lighter, less greasy finish.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Disodium EDTA chelator
- EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
- Arginine amino acid
- Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
- Portulaca Oleracea Extract plant extract
- Portulaca Oleracea is purslane. Its extract is unusually high in omega-3 fatty acids and antioxidants for a plant, and Korean formulas use it for the look of reddened, reactive skin.
- Linalool fragrance component
- Linalool is a floral aromatic found in lavender, bergamot and coriander. It is one of the 26 fragrance components EU labelling requires to be declared by name.
- Citronellol fragrance component
- Citronellol is a rose-geranium aromatic and one of the 26 fragrance components EU labelling names individually.
- Benzyl Salicylate fragrance component
- Benzyl Salicylate is a faint floral aromatic that also holds a fragrance on skin longer. It is one of the 26 fragrance components EU labelling requires to be named.
- Parfum (Fragrance) fragrance
- Fragrance, or Parfum, is a single declaration standing for a whole scent blend, which can be dozens of materials. Regulators allow it as a trade secret, so a list showing only this word does not say what the scent is made of. It is the most common trigger named by people with reactive skin.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809639172810
- Made in
- Republic of Korea
- Volume
- 35 ml
- Category
- Serum & Ampoule
- Actives
- Adenosine, Centella Asiatica, Ceramide NP, Ceramides, Green Tea, Hyaluronic Acid, Niacinamide, Panthenol, Shea Butter, Sodium Hyaluronate, Squalane
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
Inside the formula
Inside the formula
Worth knowing
- Patch test on the inner arm first if trying a new brand's formula for the first time.
- Stop use and check the ingredient list against any known sensitivities before continuing.
Complete the routine
- This itemManyo Factory Bifida Biome Concentrate Serum 35ml$37.50

- The treatment step of this routineManyo Factory Galactomy Niacin Essence 50ml$30.00

- Seal the routine in as the last stepManyo Factory Bifida Biome Concentrate Cream 50ml$47.50

Total for 3 items$115.00
Reviews
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Manyo Factory Bifida Biome Concentrate Serum 35ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
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Manyo Factory, Korean-market original
The Korean-market serum built around Bifida Ferment Lysate, from Manyo Factory, sourced for the Korean market and reviewed before it ever reaches this page.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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