MEDIHEAL
Vitamin Derma Ampoule Brightening 50ml
MEDIHEAL Vitamin Derma Ampoule Brightening 50ml is an ampoule led by Niacinamide on its own ingredient panel, sourced as the Korean-market formula.
No reviews yet50 ml
$85.00 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Normal skinDry or dehydrated skinCombination skin
- Helps with
- A formula built around NiacinamideA concentrated ampoule stepA layered Korean routine
In stock. Arrives in 3 to 7 business days
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You’re $100.00 away from free US shipping.
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- Tracked delivery to your door
Key benefits
- Niacinamide named on this product's own ingredient panel, near the top of it
- Arginine Acrylates/C10-30 Alkyl Acrylate Crosspolymer on the same panel, the formula's amino acid
- Palmitic Acid on the same panel, the formula's fatty acid
- 50 ml to a unit
- Korean-market formula, with its Korean barcode and batch code intact on the box
Key actives
3Niacinamide
Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
12Arginine Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
16Palmitic Acid
Palmitic Acid is a saturated fatty acid present in skin's own lipids. It thickens a formula, stabilises the emulsion and softens skin.
223-O-Ethyl Ascorbic Acid
3-O-Ethyl Ascorbic Acid is a stable vitamin C derivative that skin converts to ascorbic acid. It survives in a formula far better than pure vitamin C and works at a gentler pH, so it suits skin that finds the pure acid uncomfortable.
Inside the formula
Inside the formula
- 3Niacinamide
- 12Arginine Acrylates/C10-30
- 16Palmitic Acid
- 223-O-Ethyl Ascorbic
Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.
What does Niacinamide do in this ampoule?
Niacinamide sits among the first ingredients on the list, the tone-evening, barrier-supporting active Korean formulas lean on most often, and its early position here means it is not a token dose.
Is 3-O-Ethyl Ascorbic Acid also in this formula?
3-O-Ethyl Ascorbic Acid, a stabilised vitamin C derivative, sits in the middle of the ingredient list. It sits alongside Niacinamide on MEDIHEAL's ingredient list for this product.
How is this ampoule used in a routine?
Apply a small amount to cleansed skin, patting it in before the next step. A few drops is enough for the whole face. It works as a concentrated step layered under moisturiser.
Who is this ampoule suited for?
Normal skin, Dry or dehydrated skin are the best fit for this ampoule. Patch test on the inner arm before first full use, as with any new skincare product.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (51): Water, Butylene Glycol, Niacinamide, Dipropylene Glycol, Methylisothiazolinone, Glycerin, Propanediol, Diethylamino Succinate, 1,2-Hexanediol, Polyglyceryl-3 Methylglucose Distearate, Glyceryl Stearate, Arginine Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyacetophenone, Polyglyceryl-10 Laurate, Carbomer, Palmitic Acid, Polyglyceryl-4 Laurate, Stearic Acid, Ethylhexylglycerin, Xanthan Gum, Disodium Ethylenediamine Disuccinate, 3-O-Ethyl Ascorbic Acid, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Ascorbic Acid, Tocopherol, Lavandula Angustifolia Oil, Glyceryl Acrylate/Acrylic Acid Copolymer, Coptis Japonica Extract, Hydrolyzed Corn Starch, Hippophae Rhamnoides Water, Pantolactone, Caramel, Hydrogenated Lecithin, Cyperus Rotundus Root Extract, Pantothenic Acid, Arbutin, Panthenol, Tranexamic Acid, Caprylic/Capric Triglyceride, Pyridoxine, Thiamine HCl, Biotin, Folic Acid, Glutathione, Hesperidin, Riboflavin, Citronellol, Geraniol, Limonene, Linalool
Ingredient list read from mediheal.com on 10 September 2026.
46 of 51 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Propanediol humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Polyglyceryl-3 Methylglucose Distearate emulsifier
- Polyglyceryl-3 Methylglucose Distearate is a sugar-derived emulsifier known for a light, non-soapy feel. It builds gel-creams that do not read as rich.
- Glyceryl Stearate emulsifier
- Glyceryl Stearate is glycerin joined to stearic acid, and one of the most used emulsifiers in skincare. It holds oil and water together and thickens the result, and it softens skin at the same time.
- Hydroxyacetophenone preservative booster
- Hydroxyacetophenone is an antioxidant that also strengthens a preservative system, so a formula needs less traditional preservative. Korean formulas pair it with 1,2-hexanediol constantly.
- Polyglyceryl-10 Laurate emulsifier
- Polyglyceryl-10 Laurate is a sugar-derived emulsifier and solubiliser, mild enough to be a standard choice in Korean essences. It dissolves small amounts of oil into water without any tightening feel.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
34 more explained
- Palmitic Acid fatty acid
- Palmitic Acid is a saturated fatty acid present in skin's own lipids. It thickens a formula, stabilises the emulsion and softens skin.
- Polyglyceryl-4 Laurate emulsifier
- A short polyglycerin ester used as a mild emulsifier and cleansing agent. It is common in balms designed to melt on skin and then rinse away.
- Stearic Acid fatty acid
- Stearic Acid is a saturated fatty acid from plant fats, and one of the three lipid classes skin's own barrier is built from. In a formula it thickens, stabilises the emulsion and can be turned into a soap-style cleanser by adding a base.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Xanthan Gum thickener
- Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
- 3-O-Ethyl Ascorbic Acid antioxidant
- 3-O-Ethyl Ascorbic Acid is a stable vitamin C derivative that skin converts to ascorbic acid. It survives in a formula far better than pure vitamin C and works at a gentler pH, so it suits skin that finds the pure acid uncomfortable.
- Citrus Aurantium Bergamia Fruit Oil fragrance component
- Bergamot Fruit Oil is a citrus essential oil and the top note of eau de cologne. It scents a formula; citrus oils are the aromatic class most likely to bother reactive skin.
- Pelargonium Graveolens Flower Oil fragrance component
- Pelargonium Graveolens is rose geranium. Its flower oil is an essential oil used to scent a formula, carrying citronellol and geraniol.
- Ascorbic Acid antioxidant
- Ascorbic Acid is pure vitamin C, the most researched form and also the least stable: it needs a low pH and airtight packaging to stay active. It is an antioxidant used for the look of dullness and uneven tone.
- Tocopherol antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- Lavandula Angustifolia Oil fragrance component
- Lavender Oil is an essential oil carrying linalool and linalyl acetate. It scents a formula, and linalool is one of the fragrance components EU labelling requires to be named separately.
- Glyceryl Acrylate/Acrylic Acid Copolymer film former
- This is a polymer that forms a moisture-holding film on the surface, usually supplied with glycerin and propylene glycol as a hydrating complex.
- Coptis Japonica Extract plant extract
- Japanese goldthread extract, the whole plant rather than only the root. It carries berberine, is bright yellow, and is used for the look of congested skin.
- Hydrolyzed Corn Starch absorbent
- Hydrolyzed Corn Starch is starch broken into smaller fragments. It gives a silky, powdery slip and absorbs a little oil.
- Hippophae Rhamnoides Water plant extract
- Hippophae Rhamnoides is sea buckthorn. Its water is used in place of plain water as a base and carries traces of the fruit's vitamins.
- Pantolactone humectant
- Pantolactone is a panthenol relative used as a conditioning humectant. It softens the outer layer of skin and helps a formula feel comfortable.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Cyperus Rotundus Root Extract plant extract
- Nut grass root extract, a long used South Asian botanical. The tuber carries aromatic sesquiterpenes and flavonoids and is used as a conditioning extract.
- Pantothenic Acid vitamin
- Pantothenic Acid is vitamin B5, the form skin converts panthenol into. It is used as a conditioning humectant that leaves skin feeling soft rather than tight.
- Arbutin active
- Arbutin is the naturally occurring form of the same compound, from bearberry and related plants, used for the look of uneven tone. The alpha isomer is the more stable of the two.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Tranexamic Acid active
- Tranexamic Acid is a synthetic amino acid derivative used for the look of stubborn discolouration and post-blemish marks. It is water soluble, stable and comfortable next to niacinamide, which is how it is usually paired.
- Caprylic/Capric Triglyceride emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- Pyridoxine vitamin
- Pyridoxine is vitamin B6. In a formula it is a conditioning vitamin, most often in B-complex blends and scalp products.
- Thiamine HCl vitamin
- Thiamine is vitamin B1, supplied as its hydrochloride salt so it dissolves in water. It is a conditioning vitamin and usually appears as part of a B-complex.
- Biotin vitamin
- Biotin is vitamin B7. In skincare it is a conditioning vitamin, most often in hair and scalp formulas.
- Folic Acid vitamin
- Folic Acid is vitamin B9. It is used in a formula as a conditioning vitamin, usually as part of a B-complex blend.
- Glutathione antioxidant
- Glutathione is a small peptide the body uses as one of its main antioxidants. In skincare it is used as an antioxidant and for the look of dullness; it is unstable in water, so formulas that carry it are usually built around protecting it.
- Hesperidin antioxidant
- Hesperidin is the main flavonoid of citrus peel. It is used as a plant antioxidant and for the look of surface vessels.
- Riboflavin vitamin
- Riboflavin is vitamin B2, and it is a strong yellow, so a formula carrying it often has a colour nobody added on purpose.
- Citronellol fragrance component
- Citronellol is a rose-geranium aromatic and one of the 26 fragrance components EU labelling names individually.
- Geraniol fragrance component
- Geraniol is a rose-scented aromatic found in geranium and citronella oils. It is one of the 26 declarable fragrance components.
- Limonene fragrance component
- Limonene is the citrus-peel aromatic. It appears here because EU labelling requires 26 fragrance components to be named individually rather than hidden inside "fragrance", and it is one of them.
- Linalool fragrance component
- Linalool is a floral aromatic found in lavender, bergamot and coriander. It is one of the 26 fragrance components EU labelling requires to be declared by name.
- Market
- Korean market, the version sold in Korea
- Made in
- Republic of Korea
- Volume
- 50 ml
- Category
- Serum & Ampoule
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How it works
Niacinamide leads the ingredient panel on this ampoule. Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists. On this panel it sits alongside Arginine Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Palmitic Acid and 3-O-Ethyl Ascorbic Acid. Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
How to use
- Apply a small amount to cleansed skin, patting it in before the next step. A few drops is enough for the whole face.
Worth knowing
- Patch test on the inner arm before first full use, as with any new skincare product.
- Introduce a new active gradually into an existing routine rather than adding several at once.
Complete the routine
- This itemMEDIHEAL Vitamin Derma Ampoule Brightening 50ml$42.50

- The treatment step of this routineMEDIHEAL Tea Tree Calming Barrier Ampoule 50ml$37.50

- Cleanse first, so the next step meets bare skinMEDIHEAL Teatree Trouble Calming Cleanser 120ml$15.00

Total for 3 items$95.00
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MEDIHEAL Vitamin Derma Ampoule Brightening 50ml
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MEDIHEAL, Korean-market original
MEDIHEAL's Vitamin Derma Ampoule Brightening 50ml, sourced for the Korean market.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.
Using topical vitamin C can result in less cell damage and better-looking skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.
Ashlyn YankeAesthetician, Cleveland Clinic
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