New Artemisia Calming Ampoule 50ml
New Artemisia Calming Ampoule 50ml is Missha's ampoule, and Trehalose sits at position 8 of 16 on its own ingredient list, the formula's clearest headline active.
No reviews yet50 ml
$75.00 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- NormalDryCombinationSensitive
- Helps with
- Concentrated treatment stepTargeted routine layerAM or PM boost
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
Missha is a mainstream Korean drugstore brand with one of the longest-running catalogs in Korean skincare, and New Artemisia Calming Ampoule 50ml is formulated as an ampoule for the Korean market rather than a US-shelf reformulation. Trehalose is a sugar-derived humectant valued in Korean formulation for holding moisture at the surface and supporting a smoother, more comfortable feel in dry conditions. It sits at position 8 of 16 ingredients on this row's own list, ahead of most of the formula's supporting agents. Chondrus Crispus Extract, a red seaweed also called Irish moss, is a mineral-rich, film-forming ingredient used in Korean marine-inspired formulas to support a smoother surface feel. The rest of the 16-ingredient list is built around base humectants and conditioning agents rather than a second headline active.
Key benefits
- Trehalose appears at position 8 of 16 on the ingredient list, ahead of most of the formula's supporting agents.
- Chondrus Crispus Extract closes out the back half of the list at position 9 of 16, a supporting rather than lead role.
- No fragrance or parfum appears on this 16-ingredient list.
- Comes sized at 50ml, the Korean-market fill rather than a US-repackaged size.
- Ships as Missha's Korean-market formula, with the Korean barcode and batch code intact on the box.
Inside the formula
Inside the formula
What is the New Artemisia Calming Ampoule 50ml?
It is Missha's ampoule. Trehalose is a sugar-derived humectant valued in Korean formulation for holding moisture at the surface and supporting a smoother, more comfortable feel in dry conditions. Apply after toner and before moisturizer, pressing a small amount evenly over the face.
What does Trehalose do in the New Artemisia Calming Ampoule 50ml?
Trehalose is a sugar-derived humectant valued in Korean formulation for holding moisture at the surface and supporting a smoother, more comfortable feel in dry conditions. It sits at position 8 of 16 on this row's own ingredient list.
Who is the New Artemisia Calming Ampoule 50ml suited for?
It suits normal, dry, combination and sensitive skin looking for concentrated treatment step. Patch test on a small area first if you are new to this formula or to the brand.
How do I use the New Artemisia Calming Ampoule 50ml?
Apply after toner and before moisturizer, pressing a small amount evenly over the face. Give it a few weeks in that slot before judging the result, since an ampoule works cumulatively rather than after one use.
Is the New Artemisia Calming Ampoule 50ml the authentic Korean-market formula?
Yes. We stock Missha's Korean-market formula rather than a version reformulated for US shelves. What ships is the 50ml unit sold on Korean shelves, with the Korean barcode and batch code intact on the box.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (15): Artemisia Annua Extract, Glycerin, Butylene Glycol, Water, 1,2-Hexanediol, Betaine, Trehalose, Chondrus Crispus Extract, Saccharum Officinarum (Sugarcane) Extract, Carbomer, Polyacrylate Crosspolymer-6, Tromethamine, Polyquaternium-51, Ethylhexylglycerin, Disodium EDTA
Ingredient list read from jolse.com on 10 September 2026.
15 of 15 explained
- Artemisia Annua Extract plant extract
- Artemisia Annua is sweet wormwood, a mugwort relative. Its extract is used in Korean formulas for the look of reactive skin.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Betaine humectant
- Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
- Trehalose humectant
- Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
- Chondrus Crispus Extract plant extract
- Chondrus Crispus is Irish moss, a red seaweed. It is loaded with carrageenan, so it hydrates and thickens at once, and it leaves a cushioned, slippery film.
- Saccharum Officinarum (Sugarcane) Extract plant extract
- Sugarcane Extract carries natural glycolic acid and sugars. In cosmetics it is used as a humectant; the acid content is far too low to work as an exfoliant.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
- Polyacrylate Crosspolymer-6 thickener
- Polyacrylate Crosspolymer-6 is a thickener chosen for a notably fresh, bouncy gel feel that breaks down to water on the skin.
- Tromethamine pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
3 more explained
- Polyquaternium-51 film former
- Polyquaternium-51 is a polymer, sometimes sold as Lipidure, built on the same phosphorylcholine structure as a cell membrane. It holds water in a film on the surface and gives a distinctive soft, dry finish.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Disodium EDTA chelator
- EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809747931835
- Made in
- Republic of Korea
- Volume
- 50 ml
- Category
- Serum & Ampoule
- Actives
- Trehalose
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Use it after your toner or essence, when the skin is still slightly damp.
- Take two or three drops, press them over the areas that need the work and then over the rest of the face.
- Seal it with your moisturiser, since an ampoule on its own leaves the surface a little tacky.
- Do not use it in place of your moisturiser, and do not start with a full pipette on skin that has not had it before.
Worth knowing
- Patch test on a small area first if you are new to this formula or to the brand.
- Introduce it gradually alongside other active steps rather than adding several new products at once.
Complete the routine
- This itemMissha New Artemisia Calming Ampoule 50ml$37.50

- From the same Korean-market lineMissha M Perfect Cover BB Cream #27 Honey Beige$15.29

- Seal the routine in as the last stepMISSHA CHOGONGJIN SOSAENG JIN EMULSION 120ml$60.00

Total for 3 items$112.79
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MISSHA New Artemisia Calming Ampoule 50ml
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Missha, Korean-market original
New Artemisia Calming Ampoule 50ml, 50ml, Trehalose at position 8 of 16.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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