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KOREAN PHARMACY

Anua

Heartleaf 70% Intense Calming Cream

Anua Heartleaf 70% Intense Calming Cream is a 50ml cream whose ingredient list carries Adenosine alongside Tocopherol and Cholesterol.

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$19.99Comparable US listings run $22.50 (3 dated US observations, checked 10 September 2026)
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Suited to
Dry skinCompromised barrierDehydrated skinDull, uneven tone
Helps with
Shoppers looking for Adenosine in a creamRoutines that want Adenosine and Tocopherol in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Adenosine cream sold on Korean shelves

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How it works

The Heartleaf 70% Intense Calming Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Adenosine, named twenty-third on its own ingredient list. The same list carries Tocopherol, Cholesterol and Ceramide NP, so the active is not the only thing on it worth naming. How much of the Adenosine stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream Anua sells in Korea, Adenosine and all.

Key benefits

  • Adenosine, the active this cream is built around
  • Tocopherol on the same list, an antioxidant
  • Cholesterol and Ceramide NP on the same list, barrier lipids
  • Hydrogenated Poly(C6-14 Olefin) on the same list, an emollient
  • Hydrogenated Polydecene and Dicaprylyl Ether further down the same list
  • Vegetable Oil and Panthenol further down the same list

Key actives

Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. On this cream's own ingredient list it is named twenty-third.

Tocopherolantioxidant

Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer. The panel names it twenty-fifth on this cream's list, beside Adenosine.

Cholesterolbarrier lipid

Cholesterol is the third of the three lipids the outer layer of skin is built from, with ceramides and fatty acids. Formulas that carry all three are following the ratio skin itself holds. The panel names it twenty-first on this cream's list, beside Adenosine.

Ceramide NPbarrier lipid

Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy. The panel names it twenty-fourth on this cream's list, beside Adenosine.

Hydrogenated Poly(C6-14 Olefin)emollient

Hydrogenated Poly(C6-14 Olefin) is a synthetic hydrocarbon emollient. It gives a smooth, silicone-like glide and is completely stable, so it does not go rancid. The panel names it fifth on this cream's list, beside Adenosine.

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Anua Heartleaf 70% Intense Calming Cream

Anua Heartleaf 70% Intense Calming Cream

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How to use

  1. Use the Heartleaf 70% Intense Calming Cream as the last skincare step, morning and evening, over serum.
  2. A pea for the face and another for the neck. Warm it between fingertips first so it spreads in one pass.
  3. It closes the routine at night, and in the morning it is the layer sunscreen goes over.
  4. Twice a day. Do not skip it on an oily day; without a sealing layer the water the steps beneath it brought in leaves again.

Worth knowing

  • Patch test this cream on a small area and wait a day before using it more widely, especially with Adenosine on the list.
  • Introduce this cream on its own for the first week, so anything your skin does is traceable to the Adenosine rather than to three changes at once.

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Anua, Korean-market original

The Original Korean Formula cream from Anua, 50ml formulated with Adenosine and Tocopherol, held in the United States and shipped domestically.

Verify your unit when it arrives

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Anua uses a holographic QR seal that only the HiddenTag app can read. Install HiddenTag from your phone’s app store and scan the seal on the box. A camera app alone will not resolve it.

Source: Anua packaging, HiddenTag scheme

On the unit itself

  • The Korean-market barcode, unaltered from the retail package.
  • The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What professionals say

What skin-care professionals say about skin care, quoted from the medical sources linked beside each.

  • People with dry, flaky skin are more likely to see a benefit from using vitamin E because it enhances moisturization.

    Amy Kassouf, MDDermatologist, Cleveland Clinic
  • Pretty much every step of a Korean skin care routine is going to have some component of hydration.

    Alok Vij, MDDermatologist, Cleveland Clinic

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