Where does this cream go in my routine?

As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Lactobacillus Ferment Lysate and not three changes at once.

Is this the Korean-market cream or a US version?

The Korean-market one, Lactobacillus Ferment Lysate and all. We match this cream to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.

Does this cream contain fragrance?

Yes. The ingredient list names Fragrance. It sits on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this cream is not the one.

What else is on the list besides Lactobacillus Ferment Lysate?

Adenosine, Nonapeptide-1 and Acetyl Tetrapeptide-9. The order they are printed in on this cream's panel is the order on the box, so you can see where Lactobacillus Ferment Lysate sits relative to them. Further down the same panel: Acetyl Tetrapeptide-5, Acetyl Hexapeptide-1 and Acetyl Hexapeptide-8.

BIO HEAL BOH

Probioderm 3D Lifting Cream 50ml

Name: BIO HEAL BOH Probioderm 3D Lifting Cream 50ml
Brand: BIO HEAL BOH
SKU: 9736916083
Price: 60.5 USD
Availability: InStock

PROBIODERM 3D Lifting Cream is BIO HEAL BOH's cream, built around Lactobacillus Ferment Lysate, Limnanthes Alba (Meadowfoam) Seed Oil and Betaine on its own Korean-market ingredient list, sourced here as the authentic formula sold in Korea rather than a US-shelf reformulation.

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$60.50

50 ml

Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: Dehydrated skinSensitive skinSkin that has lost bounceDull, uneven tone

Helps with: Shoppers looking for Lactobacillus Ferment Lysate in a creamRoutines that want Lactobacillus Ferment Lysate and Adenosine in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Lactobacillus Ferment Lysate cream sold on Korean shelves

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Key benefits

Lactobacillus Ferment Lysate, the ferment this cream is built around
Adenosine on the same list, an active
Nonapeptide-1, Acetyl Tetrapeptide-9 and Acetyl Tetrapeptide-5 on the same list, peptides
Acetyl Hexapeptide-1 and Acetyl Hexapeptide-8 further down the same list
Palmitoyl Tripeptide-8 and Dipeptide Diaminobutyroyl Benzylamide Diacetate further down the same list
Lactobacillus Ferment Lysate named second on the manufacturer list printed on this page

Key actives

2Lactobacillus Ferment Lysateferment

Lactobacillus Ferment Lysate is the ferment with the bacterial cells broken open, so their contents are in the formula too. It is a conditioning ferment used in barrier-focused products. The name on the box points at it, and it is named second on this cream's own ingredient list.

26Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. It is named twenty-sixth on this cream's list, alongside Lactobacillus Ferment Lysate.

29Nonapeptide-1peptide

Nonapeptide-1 is a nine-amino-acid peptide used for the look of uneven tone rather than for firmness, which makes it unusual among cosmetic peptides. The panel names it twenty-ninth on this cream's list, beside Lactobacillus Ferment Lysate.

30Acetyl Tetrapeptide-9peptide

Acetyl Tetrapeptide-9 is a four-amino-acid peptide used for the look of firmness and density. It is most often supplied alongside acetyl tetrapeptide-11. The panel names it thirtieth on this cream's list, beside Lactobacillus Ferment Lysate.

31Acetyl Tetrapeptide-5peptide

Acetyl Tetrapeptide-5 is a four-amino-acid peptide used in eye products for the look of puffiness and crepiness. It is named thirty-first on this cream's list, alongside Lactobacillus Ferment Lysate.

Inside the formula

Ingredients declared

Last

Fragrance on the list

2Lactobacillus Ferment26Adenosine31Acetyl Tetrapeptide-5

2Lactobacillus Ferment
26Adenosine
31Acetyl Tetrapeptide-5

Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.

1 of 2

76 of 79 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Lactobacillus Ferment Lysate ferment: Lactobacillus Ferment Lysate is the ferment with the bacterial cells broken open, so their contents are in the formula too. It is a conditioning ferment used in barrier-focused products.
Glycerine humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Dipropylene Glycol humectant: Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
Caprylic/Capric Triglyceride emollient: Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
Cetearyl Alcohol fatty alcohol: Cetearyl Alcohol is a waxy solid, not the drying kind of alcohol. It is a blend of cetyl and stearyl alcohols used to thicken a cream and keep oil and water from separating, and it softens skin as it does so.
Limnanthes Alba (Meadowfoam) Seed Oil emollient: Meadowfoam Seed Oil is over 95 percent long-chain fatty acids, which makes it exceptionally stable against going rancid. It is an emollient that leaves a soft, sealed feel.
Glycereth-26 humectant: Glycereth-26 is a modified glycerin that hydrates with far less stickiness than glycerin itself. It is a common way to load water into a formula that has to stay light.
Vinyl Dimethicone silicone: Vinyl Dimethicone is a silicone used as a building block of the crosspolymer gels that give a formula its soft, blurring feel.
Hydrogenated Poly(C6-14 Olefin) emollient: Hydrogenated Poly(C6-14 Olefin) is a synthetic hydrocarbon emollient. It gives a smooth, silicone-like glide and is completely stable, so it does not go rancid.
Hydrogenated Polydecene emollient: Hydrogenated Polydecene is a synthetic hydrocarbon emollient used in place of mineral oil. It is stable, has no scent, and gives a cushioned slip without oxidising.
Polyglyceryl-3 Methylglucose Distearate emulsifier: Polyglyceryl-3 Methylglucose Distearate is a sugar-derived emulsifier known for a light, non-soapy feel. It builds gel-creams that do not read as rich.

64 more explained

Glyceryl Stearate emulsifier: Glyceryl Stearate is glycerin joined to stearic acid, and one of the most used emulsifiers in skincare. It holds oil and water together and thickens the result, and it softens skin at the same time.
Betaine humectant: Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
Polyglycerin-3 humectant: Polyglycerin-3 is a short chain of glycerin units used as a gentler, less sticky humectant. It also helps oils and water stay blended.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Cetearyl Olivate emulsifier: Cetearyl Olivate is the water-loving half of the olive-derived emulsifier pair. With sorbitan olivate it builds emulsions whose lipid profile is close to skin's own.
Pentylene Glycol humectant: Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate barrier lipid: An amino-acid-based lipid built on plant sterols. It structures the oil phase of a cream and echoes the lipid mix that already sits between skin cells.
Lactobacillus Ferment ferment: Lactobacillus Ferment is the liquid left after lactobacillus bacteria have fermented a plant or milk substrate. It carries the small molecules the fermentation produced, including lactic acid and amino acids, and is used for the look of dull, uneven skin.
Fructooligosaccharides humectant: Fructooligosaccharides are short fructose chains used as humectants and as food for the skin's own resident microbes.
Fructan humectant: Fructan is a chain of fructose units, usually from chicory. It holds water at the surface and forms a light, conditioning film.
Inulin polysaccharide: Inulin is a plant fructan, most often from chicory root. It holds water and, in a formula, feeds the beneficial bacteria on the surface.
Panthenol humectant: Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
Beta-Glucan polysaccharide: Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
Adenosine active: Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
Soluble Proteoglycan protein: A proteoglycan is a protein with sugar chains attached, the same architecture as the water-holding molecules in cartilage and skin. Made soluble, it is used as a humectant and conditioning protein.
Nonapeptide-1 peptide: Nonapeptide-1 is a nine-amino-acid peptide used for the look of uneven tone rather than for firmness, which makes it unusual among cosmetic peptides.
Acetyl Tetrapeptide-9 peptide: Acetyl Tetrapeptide-9 is a four-amino-acid peptide used for the look of firmness and density. It is most often supplied alongside acetyl tetrapeptide-11.
Acetyl Tetrapeptide-5 peptide: Acetyl Tetrapeptide-5 is a four-amino-acid peptide used in eye products for the look of puffiness and crepiness.
Acetyl Hexapeptide-1 peptide: Acetyl Hexapeptide-1 is a six-amino-acid peptide used for the look of even tone. It is one of the few peptides aimed at pigment rather than at lines.
Acetyl Hexapeptide-8 peptide: Acetyl Hexapeptide-8 is a six-amino-acid peptide used for the look of expression lines, particularly around the eyes. It is the peptide sold under the name Argireline and is water soluble and stable.
Palmitoyl Tripeptide-8 peptide: A three-amino-acid peptide with a palmitic acid tail, which lets it sit in the oil phase. It is used for the look of reddened, reactive skin.
Dipeptide Diaminobutyroyl Benzylamide Diacetate peptide: This is a two-amino-acid peptide, sold as Syn-Ake, used for the look of expression lines. Its structure was modelled on a component of snake venom, though nothing of the venom itself is in it.
Copper Tripeptide-1 peptide: Copper Tripeptide-1 is three amino acids bound to a copper ion, and the classic firming peptide in cosmetic chemistry. It is blue in solution, which is often why a serum carrying it is tinted, and it is used for the look of firmness and fine lines.
Tripeptide-1 peptide: Tripeptide-1 is the copper-free version of the classic three-amino-acid peptide. It is used for the look of firmness in formulas that avoid copper's blue tint.
Palmitoyl Tetrapeptide-7 peptide: Palmitoyl Tetrapeptide-7 is a four-amino-acid peptide with a fatty tail, used for the look of fine lines. With palmitoyl tripeptide-1 it forms the pairing sold as Matrixyl 3000.
Palmitoyl Tripeptide-1 peptide: Palmitoyl Tripeptide-1 is a short peptide with a fatty tail added so it can travel through the oily outer layer of skin. It is used for the look of firmness and is almost always paired with palmitoyl tetrapeptide-7.
Palmitoyl Tripeptide-5 peptide: Palmitoyl Tripeptide-5 is a fatted three-amino-acid peptide used for the look of firmness and fine lines. The palmitoyl tail is what lets it cross an oily surface.
Palmitoyl Pentapeptide-4 peptide: Palmitoyl Pentapeptide-4 is the five-amino-acid peptide originally sold as Matrixyl. It is used for the look of fine lines and is one of the longest-standing cosmetic peptides.
Palmitoyl Hexapeptide-12 peptide: Palmitoyl Hexapeptide-12 is a fatted six-amino-acid peptide used for the look of firmness, usually as part of a multi-peptide blend.
Pentapeptide-3 peptide: Pentapeptide-3 is a five-amino-acid peptide used for the look of expression lines. It is water soluble and is supplied as one part of a peptide blend rather than alone.
Hexapeptide-9 peptide: Hexapeptide-9 is a six-amino-acid peptide used for the look of firmness and elasticity. It is water soluble and appears in peptide blends rather than alone.
Oligopeptide-2 peptide: Oligopeptide-2 is a short synthetic peptide, water soluble like most of the unmodified oligopeptides. It is supplied as one component of a blend.
Malt Extract plant extract: Malt Extract comes from sprouted barley and carries sugars, amino acids and B vitamins. It is used as a conditioning, hydrating extract.
Dioscorea Japonica Root Extract plant extract: Dioscorea Japonica is Japanese wild yam, whose root is naturally slippery with mucilage. Its extract hydrates and leaves a cushioned feel.
Elaeis Guineensis (Palm) Oil emollient: Palm Oil is a rich emollient high in palmitic and oleic acids. In skincare it is more often a source material for esters and emulsifiers than an ingredient on its own.
Behenyl Alcohol fatty alcohol: Behenyl Alcohol is a long-chain fatty alcohol used to thicken and stabilise a cream. It gives a richer, more velvety body than cetyl alcohol.
Sorbitan Olivate emulsifier: Sorbitan Olivate is an olive-derived emulsifier, the oil-loving half of the pair sold as Olivem. It holds oil into water and leaves a light, non-waxy feel.
Butyrospermum Parkii (Shea) Butter emollient: Shea Butter is the fat pressed from the shea nut, rich in oleic and stearic acids and unsaponifiable plant sterols. It is a heavy emollient and partial occlusive, which is why it sits in balms and night creams rather than in essences.
Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate emollient: A thick rosin-bearing ester used in lip products for shine and staying power. It is what makes a gloss cling rather than slide off.
Hydroxyacetophenone preservative booster: Hydroxyacetophenone is an antioxidant that also strengthens a preservative system, so a formula needs less traditional preservative. Korean formulas pair it with 1,2-hexanediol constantly.
Sodium Polyacrylate thickener: Sodium Polyacrylate is a polymer that absorbs many times its weight in water. It thickens a formula and holds water in a gel against the skin.
Hydrolyzed Jojoba Esters emollient: Jojoba Esters are jojoba wax rebuilt into a softer, meltable form. They condition skin and give body to balms without the heaviness of a butter.
PEG-100 Stearate emulsifier: PEG-100 Stearate is a water-loving emulsifier almost always paired with glyceryl stearate. Together they form the standard cream base of the last fifty years.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener: This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
Xanthan Gum thickener: Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
Tromethamine pH adjuster: Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Maltodextrin film former: Maltodextrin is a starch-derived sugar chain used to carry powdered extracts and to form a light film. It also gives a soft, smoothing feel.
Cyanocobalamin vitamin: Cyanocobalamin is vitamin B12, and it is a deep pink-red, which is why a formula carrying it often has a colour nobody added on purpose. It is used as a conditioning vitamin.
Cetyl Ethylhexanoate emollient: Cetyl Ethylhexanoate is a synthetic ester used as a dry-feeling emollient. It spreads easily, leaves a silky rather than oily finish, and helps disperse pigments and UV filters evenly.
Propanediol humectant: Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
Cetearyl Glucoside emulsifier: Cetearyl Glucoside is a sugar-derived emulsifier used to hold oil and water together in creams with a light finish.
Algin thickener: Algin is a brown-seaweed polysaccharide. It thickens, forms a film, and sets into a rubbery gel when calcium is added, which is how a peel-off modelling mask works.
Sodium Stearoyl Glutamate emulsifier: Sodium Stearoyl Glutamate is an amino-acid-derived emulsifier. It holds oil and water together and is mild enough for formulas built for reactive skin.
Tocopherol antioxidant: Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
Biosaccharide Gum-4 polysaccharide: A fermentation made sugar polymer, from the same family as Biosaccharide Gum-1 but a different sugar composition. It holds water and leaves a smooth, non-tacky film.
Mineral Salts mineral: Mineral Salts is a collective declaration for the dissolved minerals in a water source such as sea water or thermal water. It describes the water rather than an added active.
Hydrolyzed Corn Starch absorbent: Hydrolyzed Corn Starch is starch broken into smaller fragments. It gives a silky, powdery slip and absorbs a little oil.
Sodium Phosphate pH adjuster: Sodium Phosphate is a buffer salt. It holds a formula at a steady pH so its actives stay in the form they work in.
Caprylyl Glycol preservative booster: Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
Sucrose humectant: Sucrose is table sugar, used here as a humectant. It draws water into the outer layer of skin and, in a scrub, doubles as the physical grain.
Dextran polysaccharide: Dextran is a branched sugar polymer made by fermenting sucrose. It holds water, thickens slightly, and is used as a carrier that keeps other water-soluble ingredients evenly spread.
Fragrance fragrance: Fragrance, or Parfum, is a single declaration standing for a whole scent blend, which can be dozens of materials. Regulators allow it as a trade secret, so a list showing only this word does not say what the scent is made of. It is the most common trigger named by people with reactive skin.

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How it works

The PROBIODERM 3D Lifting Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The ferment it is built around is Lactobacillus Ferment Lysate, named second on its own ingredient list. The same list carries Adenosine, Nonapeptide-1 and Acetyl Tetrapeptide-9, so the ferment is not the only thing on it worth naming. How much of the Lactobacillus Ferment Lysate stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream BIO HEAL BOH sells in Korea, Lactobacillus Ferment Lysate and all.

How to use

Use the PROBIODERM 3D Lifting Cream as the last skincare step, morning and evening, over serum.
Scoop out a dime-sized amount of the cream. Smooth it evenly over your face and neck, following your skin's natural lines. Gently pat to help it absorb. Use BIOHEAL BOH Probioderm 3D Lifting Cream morning and night as part of your daily skin care routine.
It closes the routine at night, and in the morning it is the layer sunscreen goes over.
Twice a day. Do not skip it on an oily day; without a sealing layer the water the steps beneath it brought in leaves again.

Worth knowing

Patch test this cream on a small area and wait a day before using it more widely, especially with Lactobacillus Ferment Lysate on the list.
This list names Fragrance, so skip it if fragrance components are something you avoid.

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BIO HEAL BOH Probioderm 3D Lifting Cream 50ml

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BIO HEAL BOH, Korean-market original

The Original Korean Formula cream from BIO HEAL BOH, 50ml formulated with Lactobacillus Ferment Lysate and Adenosine, shipped from California or direct from Korea.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

Those bacteria are essential to fight infection, protect against environmental damage, regulate pH levels and keep the skin hydrated and healthy.
Shilpi Khetarpal, MDDermatologist, Cleveland Clinic
Peptides can be anti-inflammatory, and chronic inflammation damages the tissue in your skin.
Wilma Bergfeld, MDDermatologist, Cleveland Clinic

1 more professional perspective

In skin, different peptides can encourage different things, from collagen formation to a reduction in inflammation to helping with wound healing depending on their structure.
Whitney Hovenic, MDDouble board-certified dermatologist and Mohs surgeon, Women's Health