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Cicaterol Capsule Barrier Cream 50ml$37.50345 Relief Cream
A calming cream from Dr. Althea's Korean-market lineup. Niacinamide sits at position 8 of 57 on the brand's own ingredient list, a brightening and barrier-support active; Panthenol follows at position 9, a barrier-support humectant that also settles visible irritation. 50ml to a unit.
No reviews yet$23.99
50ml
$47.98 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Dry skinCompromised barrierDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Niacinamide in a creamRoutines that want Niacinamide and Adenosine in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Niacinamide cream sold on Korean shelves
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$37.50
$42.50
$16.46
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The 345 Relief Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Niacinamide, named seventh on its own ingredient list. The same list carries Adenosine, Oligopeptide-1 and Resveratrol, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream Dr.Althea sells in Korea, Niacinamide and all.
Key benefits
- Niacinamide, the active this cream is built around
- Adenosine on the same list, an active
- Oligopeptide-1 on the same list, a peptide
- Resveratrol and Tocopherol on the same list, antioxidants
- Ceramide NP and Beta-Glucan further down the same list
- Laminaria Japonica Extract and Eclipta Prostrata Extract further down the same list
Inside the formula
Inside the formula
56
Ingredients declared
No fragrance
on the list
Dr. Althea 345 Relief Cream
Where does this cream go in my routine?
As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Niacinamide and not three changes at once.
Is this the Korean-market cream or a US version?
The Korean-market one, Niacinamide and all. We match this cream to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Niacinamide?
Adenosine, Oligopeptide-1 and Resveratrol. The order they are printed in on this cream's panel is the order on the box, so you can see where Niacinamide sits relative to them. Further down the same panel: Tocopherol, Ceramide NP and Beta-Glucan.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (56): Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Niacinamide, Panthenol, Polyglycerin-3, Polyglyceryl-10 Stearate, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Melia Azadirachta Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Curcuma Longa (Turmeric) Root Extract, Ocimum Sanctum Leaf Extract, Calendula Officinalis Flower Extract, Agave Tequilana Leaf Extract, Sargassum Fulvellum Extract, Corallina Officinalis Extract, Lavandula Angustifolia (Lavender) Flower Extract, Centella Asiatica Leaf Extract, Opuntia Ficus-Indica Stem Extract, Gardenia Florida Fruit Extract, Perilla Ocymoides Leaf Extract, Hibiscus Sabdariffa Flower Extract, Sodium Hyaluronate, Hydrogenated Lecithin, Empetrum Nigrum Fruit Juice, Dicaprylyl Carbonate, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polymethylsilsesquioxane, Dipropylene Glycol, Butylene Glycol, C12-20 Alkyl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Fructooligosaccharides, Adenosine, Beta-Glucan, Glycine Soja (Soybean) Sterols, PEG-40 Castor Oil, Hydrolyzed Hyaluronic Acid, Resveratrol, Tocopherol, Ceramide NP, Oligopeptide-1, Phenoxyethanol, Potassium Sorbate
Ingredient list read from inkeedecoder.com on 10 September 2026.
53 of 56 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Propanediol humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Cyclohexasiloxane silicone
- Cyclohexasiloxane is a volatile silicone used for a light, fast-spreading feel that leaves nothing behind.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Caprylic/Capric Triglyceride emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Polyglycerin-3 humectant
- Polyglycerin-3 is a short chain of glycerin units used as a gentler, less sticky humectant. It also helps oils and water stay blended.
- Polyglyceryl-10 Stearate emulsifier
- Polyglyceryl-10 Stearate is a mild sugar-derived emulsifier that holds oil into water and thickens slightly.
- Hydrogenated Poly(C6-14 Olefin) emollient
- Hydrogenated Poly(C6-14 Olefin) is a synthetic hydrocarbon emollient. It gives a smooth, silicone-like glide and is completely stable, so it does not go rancid.
- Hydrogenated Polydecene emollient
- Hydrogenated Polydecene is a synthetic hydrocarbon emollient used in place of mineral oil. It is stable, has no scent, and gives a cushioned slip without oxidising.
41 more explained
- Laminaria Japonica Extract plant extract
- Laminaria Japonica is kombu kelp. Its extract carries alginates, minerals and iodine, and it is used as a hydrating, mineral-rich ingredient.
- Eclipta Prostrata Leaf Extract plant extract
- Eclipta Prostrata is false daisy, long used in Ayurvedic and East Asian practice. Its extract is used as a conditioning plant extract, most often in scalp and hair formulas.
- Melia Azadirachta Flower Extract plant extract
- Melia Azadirachta is neem. Its leaf and flower extracts are long-standing Ayurvedic ingredients, and Korean formulas use them in products aimed at the look of congested, blemish-prone skin.
- Houttuynia Cordata Extract plant extract
- Houttuynia Cordata is heartleaf, and it is one of the two or three anchor plants of Korean calming skincare. Its extract carries quercitrin and other flavonoids and is used for the look of redness and blemish-prone skin.
- Oenothera Biennis (Evening Primrose) Flower Extract plant extract
- Evening Primrose Flower Extract is used as a conditioning plant extract. The seed oil of the same plant is the better known part, and it is a different ingredient.
- Curcuma Longa (Turmeric) Root Extract plant extract
- Turmeric Root Extract carries curcuminoids, well studied plant antioxidants. It is used for the look of dullness and uneven tone, and it tints a formula faintly yellow.
- Ocimum Sanctum Leaf Extract plant extract
- Ocimum Sanctum is holy basil, or tulsi. Its leaf extract carries plant antioxidants and is used in formulas built for the look of stressed, reactive skin.
- Calendula Officinalis Flower Extract plant extract
- Marigold flower extract, one of the oldest plant ingredients used for the look of reddened, easily bothered skin. It carries carotenoids and flavonoids.
- Agave Tequilana Leaf Extract plant extract
- Blue agave leaf extract. It carries fructans, sugars that hold water well, and is used as a hydrating extract.
- Sargassum Fulvellum Extract plant extract
- Mojaban, a Korean brown seaweed. Its extract carries alginates, minerals and polyphenols and is used as a hydrating marine ingredient.
- Corallina Officinalis Extract plant extract
- Corallina Officinalis is coral seaweed, which holds calcium and magnesium in its structure. Its extract is used as a mineral-rich conditioning ingredient.
- Lavandula Angustifolia (Lavender) Flower Extract plant extract
- Lavender Flower Extract is the water-based extract rather than the essential oil, so it is much milder and less aromatic.
- Centella Asiatica Leaf Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Opuntia Ficus-Indica Stem Extract plant extract
- Prickly pear cactus stem extract, from the pad rather than the fruit. The pad is full of mucilage, so the extract hydrates and leaves a cushioned feel.
- Gardenia Florida Fruit Extract plant extract
- Gardenia Fruit Extract is the traditional East Asian yellow dye plant. In skincare it is used as an antioxidant extract, and it can tint a formula.
- Perilla Ocymoides Leaf Extract plant extract
- Perilla leaf extract, the same plant Korean cooking uses as kkaennip. The leaf carries rosmarinic acid and luteolin and is used as an antioxidant botanical.
- Hibiscus Sabdariffa Flower Extract plant extract
- Roselle hibiscus extract, deep red from anthocyanins and naturally acidic. It carries plant acids and is used as an antioxidant extract.
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Dicaprylyl Carbonate emollient
- Dicaprylyl Carbonate is a light, fast-spreading emollient with a notably dry finish. It is chosen where a formula has to spread thin without leaving a heavy film.
- C14-22 Alcohols fatty alcohol
- C14-22 Alcohols is a declaration for a mixture of long-chain fatty alcohols. They thicken a cream and hold the emulsion together.
- Ammonium Acryloyldimethyltaurate/VP Copolymer thickener
- This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
- Polymethylsilsesquioxane silicone
- Polymethylsilsesquioxane is a silicone resin in fine sphere form. It soft-focuses the look of pores and lines and gives a smooth, powdery finish.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- C12-20 Alkyl Glucoside emulsifier
- C12-20 Alkyl Glucoside is a sugar-derived emulsifier used in mild, plant-based cream bases.
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener
- This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Polyquaternium-51 film former
- Polyquaternium-51 is a polymer, sometimes sold as Lipidure, built on the same phosphorylcholine structure as a cell membrane. It holds water in a film on the surface and gives a distinctive soft, dry finish.
- Tromethamine pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
- Fructooligosaccharides humectant
- Fructooligosaccharides are short fructose chains used as humectants and as food for the skin's own resident microbes.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Beta-Glucan polysaccharide
- Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
- Glycine Soja (Soybean) Sterols emollient
- The sterol fraction of soybean oil. Plant sterols are structurally close to the cholesterol in skin's own lipid layer, so they soften and help the oil phase hold together.
- Hydrolyzed Hyaluronic Acid humectant
- Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
- Resveratrol antioxidant
- Resveratrol is an antioxidant from grape skin and Japanese knotweed. It is used for the look of dullness and is often paired with ferulic acid, which keeps it stable.
- Tocopherol antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- Ceramide NP barrier lipid
- Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
- Oligopeptide-1 peptide
- Oligopeptide-1 is a short synthetic peptide. Oligo means the chain is short without the name fixing its length, which is why oligopeptides appear in blends where several sequences work together.
- Phenoxyethanol preservative
- Phenoxyethanol is the most widely used cosmetic preservative outside the paraben family. It keeps a water-containing formula from growing bacteria and mould, and is capped at one percent in most markets, so it always sits low on a list.
- Potassium Sorbate preservative
- Potassium Sorbate is a preservative that holds off yeast and mould in acidic formulas. It is almost always used with sodium benzoate, because neither covers the whole range of microbes alone.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809447251394
- Made in
- Republic of Korea
- Volume
- 50ml
- Category
- Moisturizer / Soothing/calming cream
- Actives
- Adenosine, Beta-Glucan, Centella Asiatica, Ceramide NP, Heartleaf (Houttuynia Cordata), Hyaluronic Acid, Niacinamide, Panthenol, Peptides, Sodium Hyaluronate
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Use the 345 Relief Cream last in the evening, and under sunscreen in the morning.
- A pea-sized amount for the whole face, pressed in rather than rubbed, while skin is still damp from the layer before it.
- It goes on after your serum or ampoule. In the morning your sunscreen is the only thing that follows it.
- Twice a day, every day. Do not put a water-based layer on top of it, because nothing thin sits well over a seal.
Worth knowing
- Patch test this cream on a small area and wait a day before using it more widely, especially with Niacinamide on the list.
- Introduce this cream on its own for the first week, so anything your skin does is traceable to the Niacinamide rather than to three changes at once.
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Dr. Althea 345 Relief Cream
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
Creators trying on authentic Korean skincare routines and products from us.
One month of wearing the Dr. Althea 345 Relief Cream.
Aasthaetics · YouTube
Asking whether the Dr. Althea 345 Relief Cream is worth it.
alex greyson · YouTube
Rating a shelf of Dr. Althea products one by one.
Jasmine Loo · YouTube
Two hydrating serums side by side, IUNIK and Dr. Althea.
Kristin · YouTube
A walk through the Dr. Althea serum lineup and who each one suits.
auraofmahmuda · YouTube
A blunt first take on the Dr. Althea range.
Lexi Chang · YouTube
A first look at the viral 345 Relief Cream before buying.
Shelley Nayak · YouTube
A first try of the Dr. Althea serum on camera.
Hannah Ziad · YouTube
Dr.Althea, Korean-market original
The Original Korean Formula cream from Dr.Althea, 50ml formulated with Niacinamide and Adenosine, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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