Blemish Care Up Serum 25ml
isoi Blemish Care Up Serum is a 25ml serum whose ingredient list carries Arbutin alongside Allantoin and Hippophae Rhamnoides Fruit Extract.
No reviews yet25 ml
$20.00 per 10 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- NormalCombinationDryOily
- Helps with
- A targeted treatment stepLayering under a daily moisturizer
In stock. Arrives in 3 to 7 business days
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Key benefits
- Arbutin, the active this serum is built around
- Allantoin on the same list, an active
- Hippophae Rhamnoides Fruit Extract, Euterpe Oleracea (Acai) Fruit Extract and Vaccinium Angustifolium Fruit Extract on the same list, plant extracts
- Vaccinium Macrocarpon (Cranberry) Fruit Extract and Rhodiola Rosea Root Extract further down the same list
- Sophora Flavescens Root Extract and Salix Nigra (Willow) Bark Extract further down the same list
- Arbutin named fifth on the manufacturer list printed on this page
Key actives
5Arbutinactive
Arbutin is the naturally occurring form of the same compound, from bearberry and related plants, used for the look of uneven tone. The alpha isomer is the more stable of the two. On this serum's own ingredient list it is named fifth.
9Hippophae Rhamnoides Fruit Extractplant extract
Sea Buckthorn Fruit Extract is high in vitamin C and carotenoids, which give it a strong orange colour. It is used as an antioxidant extract. The panel names it ninth on this serum's list, beside Arbutin.
10Euterpe Oleracea (Acai) Fruit Extractplant extract
Acai fruit extract, from the Amazonian palm berry. It carries anthocyanins, the same purple pigment polyphenols found in blueberry, and is used as a plant antioxidant. It is named tenth on this serum's list, alongside Arbutin.
11Vaccinium Angustifolium Fruit Extractplant extract
Lowbush blueberry fruit extract, high in anthocyanins. Berry extracts are used as plant antioxidants and can tint a formula. The panel names it eleventh on this serum's list, beside Arbutin.
19Allantoinactive
Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin. It is named nineteenth on this serum's list, alongside Arbutin.
Inside the formula
Inside the formula
- 5Arbutin
- 9Hippophae Rhamnoides
- 11Vaccinium Angustifolium
- 19Allantoin
Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.
Where does this serum go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than a serum goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Arbutin and not three changes at once.
Does this serum contain fragrance?
Yes. The ingredient list names Citronellol and Geraniol. They sit on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this serum is not the one.
What else is on the list besides Arbutin?
Allantoin, Hippophae Rhamnoides Fruit Extract and Euterpe Oleracea (Acai) Fruit Extract. The order they are printed in on this serum's panel is the order on the box, so you can see where Arbutin sits relative to them. Further down the same panel: Vaccinium Angustifolium Fruit Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract and Rhodiola Rosea Root Extract.
Not on the ingredient list below: fragrance or parfum, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (36): Water, Rosa Damascena Flower Water, Glycerin, Alcohol*, Arbutin, Betaine, Trehalose, Rosa Damascena Flower Oil, Hippophae Rhamnoides Fruit Extract, Euterpe Oleracea Fruit Extract, Vaccinium Angustifolium (Blueberry) Fruit Extract, Phyllanthus Emblica Fruit Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Rhodiola Rosea Root Extract, Sophora Flavescens Root Extract, Salix Nigra (Willow) Bark Extract, Houttuynia Cordata Extract, Xanthan Gum, Allantoin, Panthenol, Rhus Semialata Gall Extract, Olea Europaea (Olive) Fruit Oil, Chrysanthemum Indicum Flower Extract, Sophora Japonica Bud Extract, Prunella Vulgaris Leaf Extract, Castanea Crenata (Chestnut) Shell Extract, Salix Alba (Willow) Bark Extract, Centella Asiatica Extract, Butylene Glycol, 1,2-Hexanediol, Calendula Officinalis Flower Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Citronellol, Geraniol
Ingredient list read from inkeedecoder.com on 10 September 2026.
31 of 36 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Rosa Damascena Flower Water plant extract
- Rosa Damascena Flower Water is the water left from distilling rose petals. It is used in place of plain water as a base and carries the scent and trace compounds of the distillation.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Alcohol* solvent
- Alcohol here means ethanol. It dissolves ingredients water cannot, evaporates fast so a formula sets quickly and does not feel heavy, and thins texture. In quantity it can leave dry or reactive skin feeling tight, which is why many Korean formulas avoid it and some deliberately use it for a fast, weightless finish.
- Arbutin active
- Arbutin is the naturally occurring form of the same compound, from bearberry and related plants, used for the look of uneven tone. The alpha isomer is the more stable of the two.
- Betaine humectant
- Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
- Trehalose humectant
- Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
- Rosa Damascena Flower Oil fragrance component
- Rosa Damascena Flower Oil is rose essential oil, one of the most expensive materials in perfumery. It scents a formula, and like every essential oil it is a class reactive skin often does not tolerate.
- Hippophae Rhamnoides Fruit Extract plant extract
- Sea Buckthorn Fruit Extract is high in vitamin C and carotenoids, which give it a strong orange colour. It is used as an antioxidant extract.
- Euterpe Oleracea Fruit Extract plant extract
- Acai fruit extract, from the Amazonian palm berry. It carries anthocyanins, the same purple pigment polyphenols found in blueberry, and is used as a plant antioxidant.
- Vaccinium Angustifolium (Blueberry) Fruit Extract plant extract
- Lowbush blueberry fruit extract, high in anthocyanins. Berry extracts are used as plant antioxidants and can tint a formula.
- Vaccinium Macrocarpon (Cranberry) Fruit Extract plant extract
- Cranberry fruit extract, acidic and high in proanthocyanidins. It is used as an antioxidant berry extract.
19 more explained
- Rhodiola Rosea Root Extract plant extract
- Roseroot extract, from an arctic and alpine plant. It carries salidroside and is used as an antioxidant conditioning extract.
- Sophora Flavescens Root Extract plant extract
- Kushen root extract, a bitter traditional herbal ingredient carrying alkaloids and flavonoids. Korean formulas use it in scalp and blemish-focused products.
- Salix Nigra (Willow) Bark Extract plant extract
- Black willow bark extract. Willow bark carries salicin and tannins, and it is the botanical route to a salicylate rather than a synthetic salicylic acid.
- Houttuynia Cordata Extract plant extract
- Houttuynia Cordata is heartleaf, and it is one of the two or three anchor plants of Korean calming skincare. Its extract carries quercitrin and other flavonoids and is used for the look of redness and blemish-prone skin.
- Xanthan Gum thickener
- Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
- Allantoin active
- Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Olea Europaea (Olive) Fruit Oil emollient
- Olive Fruit Oil is high in oleic acid and plant sterols. It is a rich emollient that suits dry skin and is heavy enough that blemish-prone skin often does not get on with it.
- Castanea Crenata (Chestnut) Shell Extract plant extract
- Chestnut Shell Extract carries tannins and is used as an antioxidant plant extract, most often in formulas aimed at visible pores.
- Salix Alba (Willow) Bark Extract plant extract
- Willow Bark Extract carries salicin, the plant compound salicylic acid is related to. The two are not interchangeable: willow bark is a mild clarifying extract, not a BHA exfoliant at the levels used in cosmetics.
- Centella Asiatica Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Calendula Officinalis Flower Extract plant extract
- Marigold flower extract, one of the oldest plant ingredients used for the look of reddened, easily bothered skin. It carries carotenoids and flavonoids.
- Scutellaria Baicalensis Root Extract plant extract
- Scutellaria Baicalensis is Chinese skullcap. Its root extract carries baicalin, a well studied plant antioxidant, and it is used for the look of redness.
- Paeonia Suffruticosa Root Extract plant extract
- Paeonia Suffruticosa is tree peony, a long-standing East Asian medicinal plant. Its root extract carries paeoniflorin and is used for the look of reddened skin.
- Glycyrrhiza Glabra (Licorice) Root Extract plant extract
- Licorice Root Extract carries glabridin and liquiritin. It is one of the classic plant ingredients used for the look of uneven tone and redness, and it appears in almost every brightening formula that avoids synthetic actives.
- Citronellol fragrance component
- Citronellol is a rose-geranium aromatic and one of the 26 fragrance components EU labelling names individually.
- Geraniol fragrance component
- Geraniol is a rose-scented aromatic found in geranium and citronella oils. It is one of the 26 declarable fragrance components.
- Market
- Korean market, the version sold in Korea
- Made in
- Republic of Korea
- Volume
- 25 ml
- Category
- Serum & Ampoule
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How it works
The Blemish Care Up Serum is a 25ml serum, used after toner and before moisturizer, morning and evening. The active it is built around is Arbutin, named fifth on its own ingredient list. The same list carries Allantoin, Hippophae Rhamnoides Fruit Extract and Euterpe Oleracea (Acai) Fruit Extract, so the active is not the only thing on it worth naming. How much of the Arbutin stays on the skin, and for how long, is decided by the serum format rather than by the list alone. isoi sells this Arbutin serum in Korea, and this is that version.
How to use
- Apply a few drops to clean skin after toner or essence and before moisturizer, morning and/or night, pressing it in rather than rubbing.
Worth knowing
- Introduce a new serum on its own for a week before adding other treatment steps.
Complete the routine
- This itemisoi Blemish Care Up Serum 25ml$50.00

- The treatment step of this routineisoi Bulgarian Rose Blemish Care Spot 25ml$45.00

- Seal the routine in as the last stepisoi Bulgarian Rose Intensive Treatment Lotion 90ml$95.00

Total for 3 items$190.00
Reviews
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isoi Blemish Care Up Serum 25ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
isoi, Korean-market original
The Original Korean Formula serum from isoi, 25ml formulated with Arbutin and Allantoin, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.
Arbutin works to inhibit tyrosinase, an enzyme present in melanocytes, the pigment-producing cells in the skin. This results in less pigment, dark spots and skin lightening.
Tiffany Jow Libby, MDBoard-certified dermatologist, mindbodygreen Allantoin can tone down the dryness of the individual cells. It increases the water content of the skin, which means it helps to hydrate and moisturize.
Wilma Bergfeld, MDDermatologist, Cleveland Clinic
1 more professional perspective
These mechanisms not only reinforce barrier function but also mitigate inflammation and accelerate healing.
Yang TangAssistant Professor, Beijing University of Chinese Medicine, Frontiers in Pharmacology
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