isoi Moisture Dr. Ampoule 40ml
isoi Moisture Dr. Ampoule is isoi's 40ml ampoule, formulated with Phytosphingosine.
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- Suited to
- Dry skinCompromised barrierDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Phytosphingosine in an ampouleRoutines that want Phytosphingosine and Ceramide NP in one stepFilling the ampoule step with a Korean-market formulaAnyone who wants the Phytosphingosine ampoule sold on Korean shelves
In stock. Ships from our California warehouse, dispatched within 2 business days
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- 30-day returns
- Free US shipping on orders of $100 or more
- Dispatched within 2 business days
Key benefits
- Phytosphingosine, the barrier lipid this ampoule is built around
- Ceramide NP on the same list, a barrier lipid
- Melaleuca Alternifolia (Tea Tree) Leaf Extract, Portulaca Oleracea Extract and Houttuynia Cordata Extract on the same list, plant extracts
- Salix Alba (Willow) Bark Extract and Origanum Vulgare Leaf Extract further down the same list
- Chamaecyparis Obtusa Leaf Extract and Cinnamomum Cassia Bark Extract further down the same list
- Phytosphingosine named twenty-fourth on the manufacturer list printed on this page
Key actives
Phytosphingosinebarrier lipid
Phytosphingosine is the backbone every ceramide is built on, and skin uses it in its own lipid layer. In a formula it works with ceramides and cholesterol and also keeps the product stable against microbes. On this ampoule's own ingredient list it is named twenty-fourth.
Ceramide NPbarrier lipid
Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy. It is named twenty-fifth on this ampoule's list, alongside Phytosphingosine.
Melaleuca Alternifolia (Tea Tree) Leaf Extractplant extract
Tea Tree Leaf Extract is the water-based extract rather than the essential oil, so it is far milder and much less aromatic. It is used in formulas for blemish-prone skin. The panel names it thirteenth on this ampoule's list, beside Phytosphingosine.
Portulaca Oleracea Extractplant extract
Portulaca Oleracea is purslane. Its extract is unusually high in omega-3 fatty acids and antioxidants for a plant, and Korean formulas use it for the look of reddened, reactive skin. The panel names it fourteenth on this ampoule's list, beside Phytosphingosine.
Houttuynia Cordata Extractplant extract
Houttuynia Cordata is heartleaf, and it is one of the two or three anchor plants of Korean calming skincare. Its extract carries quercitrin and other flavonoids and is used for the look of redness and blemish-prone skin. The panel names it fifteenth on this ampoule's list, beside Phytosphingosine.
How to use
- Apply morning and night after toner or essence and before moisturizer, pressing a small amount into the skin and letting it absorb fully before the next step.
Where does this ampoule go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than an ampoule goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Phytosphingosine and not three changes at once.
Is this the Korean-market ampoule or a US version?
The Korean-market one, Phytosphingosine and all. We match this ampoule to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
Does this ampoule contain fragrance?
Yes. The ingredient list names Limonene. It sits on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this ampoule is not the one.
What else is on the list besides Phytosphingosine?
Ceramide NP, Melaleuca Alternifolia (Tea Tree) Leaf Extract and Portulaca Oleracea Extract. The order they are printed in on this ampoule's panel is the order on the box, so you can see where Phytosphingosine sits relative to them. Further down the same panel: Houttuynia Cordata Extract, Salix Alba (Willow) Bark Extract and Origanum Vulgare Leaf Extract.
- Ships from
- California
Duties are prepaid. Nothing is owed at delivery. Returns are accepted for 30 days, by mail.
Orders ship from our California warehouse, dispatched within 2 business days, and arrive in 3 to 5 days. Shipping is free on orders of $100 or more.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Customs
Duty paid by us before it enters the US - 3California
Ships domestically, no international leg
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Import duties are paid by us before the parcel reaches you, so nothing is owed at the door, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
Payment and security
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How it works
The Moisture Dr. Ampoule is a 40ml ampoule, used after toner and before moisturizer, morning and evening. The barrier lipid it is built around is Phytosphingosine, named twenty-fourth on its own ingredient list. The same list carries Ceramide NP, Melaleuca Alternifolia (Tea Tree) Leaf Extract and Portulaca Oleracea Extract, so the barrier lipid is not the only thing on it worth naming. How much of the Phytosphingosine stays on the skin, and for how long, is decided by the ampoule format rather than by the list alone. This is the Original Korean Formula, the ampoule isoi sells in Korea, Phytosphingosine and all.
Worth knowing
- Patch test this ampoule on a small area and wait a day before using it more widely, especially with Phytosphingosine on the list.
- This list names Limonene, so skip it if fragrance components are something you avoid.
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Korean-market original
The Original Korean Formula ampoule from isoi, 40ml formulated with Phytosphingosine and Ceramide NP, held in the United States and shipped domestically.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
Match the batch code on the box against the code printed on the bottle or tube itself; the two are stamped separately and should agree.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.
Phytosphingosine is considered a precursor to ceramides, which are the dominant fat that fills in the cracks between skin cells.
Joshua Zeichner, MDDermatologist, director of cosmetic and clinical research, Mount Sinai Hospital, Healthline Ceramides are part fatty acid and part amino acid and are able to be the grout that keeps the building blocks of the skin together and functioning as a barrier between the inside and outside world.
Amy Kassouf, MDDermatologist, Cleveland Clinic
1 more professional perspective
I think it's fair to say I've seen lots of patients use tea tree oil for a variety of skin issues. It's a natural remedy that is known to help.
Simon Hodes, MB ChBFamily physician, Cleveland Clinic
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