Moisture Dr. Ampoule 40ml
isoi Moisture Dr. Ampoule is isoi's 40ml ampoule, formulated with Phytosphingosine.
No reviews yet40 ml
$93.75 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Dry skinCompromised barrierDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Phytosphingosine in an ampouleRoutines that want Phytosphingosine and Ceramide NP in one stepFilling the ampoule step with a Korean-market formulaAnyone who wants the Phytosphingosine ampoule sold on Korean shelves
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The Moisture Dr. Ampoule is a 40ml ampoule, used after toner and before moisturizer, morning and evening. The barrier lipid it is built around is Phytosphingosine, named twenty-fourth on its own ingredient list. The same list carries Ceramide NP, Melaleuca Alternifolia (Tea Tree) Leaf Extract and Portulaca Oleracea Extract, so the barrier lipid is not the only thing on it worth naming. How much of the Phytosphingosine stays on the skin, and for how long, is decided by the ampoule format rather than by the list alone. This is the Original Korean Formula, the ampoule isoi sells in Korea, Phytosphingosine and all.
Key benefits
- Phytosphingosine, the barrier lipid this ampoule is built around
- Ceramide NP on the same list, a barrier lipid
- Melaleuca Alternifolia (Tea Tree) Leaf Extract, Portulaca Oleracea Extract and Houttuynia Cordata Extract on the same list, plant extracts
- Salix Alba (Willow) Bark Extract and Origanum Vulgare Leaf Extract further down the same list
- Chamaecyparis Obtusa Leaf Extract and Cinnamomum Cassia Bark Extract further down the same list
- Phytosphingosine named twenty-fourth on the manufacturer list printed on this page
Inside the formula
Inside the formula
Where does this ampoule go in my routine?
After toner and before moisturizer, morning and evening. Anything thinner than an ampoule goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Phytosphingosine and not three changes at once.
Is this the Korean-market ampoule or a US version?
The Korean-market one, Phytosphingosine and all. We match this ampoule to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
Does this ampoule contain fragrance?
Yes. The ingredient list names Limonene. It sits on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this ampoule is not the one.
What else is on the list besides Phytosphingosine?
Ceramide NP, Melaleuca Alternifolia (Tea Tree) Leaf Extract and Portulaca Oleracea Extract. The order they are printed in on this ampoule's panel is the order on the box, so you can see where Phytosphingosine sits relative to them. Further down the same panel: Houttuynia Cordata Extract, Salix Alba (Willow) Bark Extract and Origanum Vulgare Leaf Extract.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (37): Water, Glycerin, Betaine, Trehalose, Squalane, Caprylic/Capric Triglyceride, Panthenol, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Glycosaminoglycans, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Salix Alba (Willow) Bark Extract, Origanum Vulgare Leaf Extract, Chamaecyparis Obtusa Leaf Extract, Lactobacillus/Soybean Ferment Extract, Cinnamomum Cassia Bark Extract, Arginine, Carbomer, Macadamia Ternifolia Seed Oil, Phytosphingosine, Ceramide NP, Xanthan Gum, Citrus Paradisi (Grapefruit) Peel Oil, Sorbitan Sesquioleate, Butylene Glycol, 1,2-Hexanediol, Propanediol, Calendula Officinalis Flower Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, Glycyrrhiza Glabra (Licorice) Extract, Hydrogenated Lecithin, Limonene
Ingredient list read from inkeedecoder.com on 10 September 2026.
36 of 37 explained
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Betaine humectant
- Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
- Trehalose humectant
- Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
- Squalane emollient
- Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
- Caprylic/Capric Triglyceride emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Sodium Hyaluronate humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- Hydrolyzed Hyaluronic Acid humectant
- Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
- Hyaluronic Acid humectant
- Hyaluronic Acid is a sugar chain the body already makes, and one gram of it can hold several litres of water. In a formula it is a humectant that pulls water to the surface of skin and holds it in a film, which is what makes skin look plumper while it is there.
- Sodium Hyaluronate Crosspolymer humectant
- Sodium Hyaluronate Crosspolymer is hyaluronic acid linked into a mesh. It holds water in a soft gel on the surface rather than sinking in, and it releases that water slowly through the day.
- Hydrolyzed Glycosaminoglycans humectant
- Hydrolyzed Glycosaminoglycans are short fragments of the sugar chains that sit between cells in skin, hyaluronic acid among them. They act as humectants and give a cushioned feel.
24 more explained
- Melaleuca Alternifolia (Tea Tree) Leaf Extract plant extract
- Tea Tree Leaf Extract is the water-based extract rather than the essential oil, so it is far milder and much less aromatic. It is used in formulas for blemish-prone skin.
- Portulaca Oleracea Extract plant extract
- Portulaca Oleracea is purslane. Its extract is unusually high in omega-3 fatty acids and antioxidants for a plant, and Korean formulas use it for the look of reddened, reactive skin.
- Houttuynia Cordata Extract plant extract
- Houttuynia Cordata is heartleaf, and it is one of the two or three anchor plants of Korean calming skincare. Its extract carries quercitrin and other flavonoids and is used for the look of redness and blemish-prone skin.
- Salix Alba (Willow) Bark Extract plant extract
- Willow Bark Extract carries salicin, the plant compound salicylic acid is related to. The two are not interchangeable: willow bark is a mild clarifying extract, not a BHA exfoliant at the levels used in cosmetics.
- Origanum Vulgare Leaf Extract plant extract
- Oregano leaf extract, rich in the phenols carvacrol and thymol. It is used as an antioxidant plant extract and brings its own herbal scent with it.
- Chamaecyparis Obtusa Leaf Extract plant extract
- Chamaecyparis Obtusa is hinoki cypress. Its leaf extract carries aromatic plant compounds and is used in Korean formulas aimed at oily, congested skin.
- Lactobacillus/Soybean Ferment Extract ferment
- This is soybean fermented by lactobacillus. The fermentation breaks soy proteins into smaller pieces, which is what makes the extract easier for a formula to carry.
- Cinnamomum Cassia Bark Extract plant extract
- Cassia cinnamon bark extract, a traditional herbal ingredient carrying cinnamaldehyde and tannins. It is used in warming, antioxidant-rich blends.
- Arginine amino acid
- Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
- Macadamia Ternifolia Seed Oil emollient
- Macadamia Seed Oil is unusually high in palmitoleic acid, a fatty acid that human sebum also contains, which is why it absorbs faster than most nut oils. It is a cushioning emollient for dry skin.
- Phytosphingosine barrier lipid
- Phytosphingosine is the backbone every ceramide is built on, and skin uses it in its own lipid layer. In a formula it works with ceramides and cholesterol and also keeps the product stable against microbes.
- Ceramide NP barrier lipid
- Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
- Xanthan Gum thickener
- Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
- Citrus Paradisi (Grapefruit) Peel Oil fragrance component
- Grapefruit peel oil, an essential oil pressed from the rind. It scents a formula, and citrus peel oils can make skin more sensitive to sun.
- Sorbitan Sesquioleate emulsifier
- Sorbitan Sesquioleate is a water-in-oil emulsifier and pigment disperser. Cleansing oils use it so water can be worked into the oil at the rinse.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Propanediol humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- Calendula Officinalis Flower Extract plant extract
- Marigold flower extract, one of the oldest plant ingredients used for the look of reddened, easily bothered skin. It carries carotenoids and flavonoids.
- Scutellaria Baicalensis Root Extract plant extract
- Scutellaria Baicalensis is Chinese skullcap. Its root extract carries baicalin, a well studied plant antioxidant, and it is used for the look of redness.
- Paeonia Suffruticosa Root Extract plant extract
- Paeonia Suffruticosa is tree peony, a long-standing East Asian medicinal plant. Its root extract carries paeoniflorin and is used for the look of reddened skin.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Limonene fragrance component
- Limonene is the citrus-peel aromatic. It appears here because EU labelling requires 26 fragrance components to be named individually rather than hidden inside "fragrance", and it is one of them.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809264737194
- Made in
- Republic of Korea
- Volume
- 40 ml
- Category
- Serum & Ampoule
- Actives
- Ceramide NP, Heartleaf (Houttuynia Cordata), Hyaluronic Acid, Licorice Root, Panthenol, Sodium Hyaluronate, Squalane, Tea Tree, Trehalose
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Apply morning and night after toner or essence and before moisturizer, pressing a small amount into the skin and letting it absorb fully before the next step.
Worth knowing
- Patch test this ampoule on a small area and wait a day before using it more widely, especially with Phytosphingosine on the list.
- This list names Limonene, so skip it if fragrance components are something you avoid.
Complete the routine
- This itemisoi Moisture Dr. Ampoule 40ml$37.50
- The treatment step of this routineisoi Bulgarian Rose Blemish Care Spot 25ml$45.00
- Seal the routine in as the last stepisoi Bulgarian Rose Intensive Treatment Lotion 90ml$95.00
Total for 3 items$177.50
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isoi Moisture Dr. Ampoule 40ml
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isoi, Korean-market original
The Original Korean Formula ampoule from isoi, 40ml formulated with Phytosphingosine and Ceramide NP, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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