Where does this formula come from?

It comes from the Korean-market catalog rather than a US-shelf reformulation, and the packaging carries the same Korean-market batch coding a shopper would find on the box in Korea. That sourcing is checked on this row before the page is written, not assumed from the product name. It is the detail worth checking against the box on arrival.

Can I use this alongside other actives in my routine?

Yes. Glycerin is the lead active here, and it is formulated to sit alongside the rest of a routine rather than replace it. Introduce any new step on its own for the first week or two before adding it next to another strong active, so it is easy to tell which product is responsible for any change. Once it is settled into the routine, it layers the way any other essence in a Korean routine does.

How do I know this is authentic and not a US-reformulated version?

Check the box against the listing: an authentic Korean-market SKU carries Korean-primary packaging and an intact Korean-market batch code, not a US-only relabel. Numbuzin's Korean-market formulas are sourced specifically to preserve that, rather than substituted for the US-shelf version some retailers carry under the same name.

What does Niacinamide do in this formula?

Niacinamide supports an even-looking skin tone and works alongside the formula's humectants to keep the surface comfortable. It is one of the most studied actives in Korean formulation for tone evenness and is gentle enough for daily AM and PM use. It sits at its own position on this product's own ingredient list rather than being assumed from the product name.

Numbuzin

No.9 NMN BIO Lifting-Sil Essence 50ml

Name: Numbuzin No.9 NMN BIO Lifting-Sil Essence 50ml
Brand: Numbuzin
SKU: 11236295112
Price: 45.0 USD
Availability: InStock

Numbuzin No.9 NMN BIO Lifting-Sil Essence 50ml carries 48 separate peptide forms on its own ingredient panel, including Palmitoyl Tripeptide-5, Capryloyl Dipeptide-17, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate.

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$45.00

50 ml

$90.00 per 100 ml

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: normalcombinationdryoily

Helps with: tone and texture supported by Glycerindaily hydration through the essence stepa Korean-market formula rather than a US reformulationa routine step matched to this format

One-time purchase

$45.00

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$40.50

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Key benefits

48 forms of peptide on one panel, not a single token inclusion
Niacinamide on the same panel, the formula's active
Hydrogenated Vegetable Oil on the same panel, the formula's occlusive
50 ml to a unit
Korean-market formula, with its Korean barcode and batch code intact on the box

Key actives

10Niacinamide

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.

All products with Niacinamide

14Hydrogenated Vegetable Oil

Plant oil hardened by hydrogenation. It behaves as a soft solid, so it gives balms and sticks their body and slows water loss from the surface.

All products with Hydrogenated Vegetable Oil

26Adenosine

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.

All products with Adenosine

37Palmitoyl Tripeptide-5

Palmitoyl Tripeptide-5 is a fatted three-amino-acid peptide used for the look of firmness and fine lines. The palmitoyl tail is what lets it cross an oily surface.

All products with Palmitoyl Tripeptide-5

58Acetyl Dipeptide-1 Cetyl Ester

Acetyl Dipeptide-1 Cetyl Ester is a two-amino-acid peptide with a fatty cetyl tail attached, which lets it sit in the oil phase of a formula rather than only the water phase.

All products with Acetyl Dipeptide-1 Cetyl Ester

59Dipeptide Diaminobutyroyl Benzylamide Diacetate

This is a two-amino-acid peptide, sold as Syn-Ake, used for the look of expression lines. Its structure was modelled on a component of snake venom, though nothing of the venom itself is in it.

All products with Dipeptide Diaminobutyroyl Benzylamide Diacetate

Inside the formula

120

Ingredients declared

No fragrance

on the list

10Niacinamide26Adenosine37Palmitoyl Tripeptide-558Acetyl Dipeptide-1

10Niacinamide
26Adenosine
37Palmitoyl Tripeptide-5
58Acetyl Dipeptide-1

Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.

1 of 5

Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, parabens, sulfate surfactants, mineral oil or petrolatum and added color.

Full INCI (120): Water, Glycerin, Hydrogenated Poly(C6-14 Olefin), Polyglycerin-3, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Propanediol, Dimethicone, 1,2-Hexanediol, Niacinamide, Methylpropanediol, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Vegetable Oil, Polyglyceryl-3 Methylglucose Distearate, Butyrospermum Parkii (Shea) Butter, Dimethicone Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Polyacrylate, Hydrogenated Lecithin, Carbomer, Xanthan Gum, Pentylene Glycol, Tromethamine, Ethylhexylglycerin, Adenosine, Palmitic Acid, Stearic Acid, Sodium Phytate, Cholesterol, Sodium Hyaluronate, Adenosine Triphosphate, Hydroxypropyl Cyclodextrin, Nicotinamide Adenine Dinucleotide, Beta-Glucan, Tocopherol, Palmitoyl Tripeptide-5, Copper Gluconate, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Zinc Ferment, Capryloyl Dipeptide-17, Thioctic Acid, Leuconostoc/Radish Root Ferment Filtrate, Glutathione, Tremella Fuciformis (Mushroom) Extract, Haematococcus Pluvialis Oil, Potassium Hydroxide, Resveratrol, Hesperidin Methyl Chalcone, Sorbitan Laurate, Steareth-20, Astaxanthin, Sodium Lactate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Heptasodium Hexacarboxymethyl Dipeptide-12, Panthenol, Polysorbate 20, Sodium Citrate, Chlorhexidine Digluconate, Dextran, Hexapeptide-2, Magnesium Chloride, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Acetyl Tetrapeptide-5, Dipeptide-2, Potassium Sorbate, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Citric Acid, Biotin, Palmitoyl Tetrapeptide-7, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Trifolium Pratense (Clover) Flower Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-8, Dipeptide-4, Hexapeptide-11, Pentapeptide-18, Tripeptide-3, Sh-Decapeptide-7, Sh-Octapeptide-4, Palmitoyl Tripeptide-1, Ascorbic Acid Polypeptide, Hexapeptide-9, Oligopeptide-3, Palmitoyl Hexapeptide-12, Tripeptide-1, Palmitoyl Pentapeptide-4, Ubiquinone, Copper Tripeptide-1, Caffeoyl Tripeptide-1, Caffeoyl Sh-Octapeptide-4, Galloyl Pentapeptide-33, Kojyl Carboxy Dipeptide-23, Nicotinoyl Tripeptide-1, Octapeptide-7, Oligopeptide-1, Sh-Decapeptide-9, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Asparagine, Glutamine, Tryptophan, Oligopeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Sh-Polypeptide-3, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-9, Carnosine, Nonapeptide-1

Ingredient list read from jolse.com on 10 September 2026.

106 of 120 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Hydrogenated Poly(C6-14 Olefin) emollient: Hydrogenated Poly(C6-14 Olefin) is a synthetic hydrocarbon emollient. It gives a smooth, silicone-like glide and is completely stable, so it does not go rancid.
Polyglycerin-3 humectant: Polyglycerin-3 is a short chain of glycerin units used as a gentler, less sticky humectant. It also helps oils and water stay blended.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Pentaerythrityl Tetraethylhexanoate emollient: Pentaerythrityl Tetraethylhexanoate is a light ester emollient that gives a dry, silky finish and disperses pigment evenly.
Propanediol humectant: Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
Dimethicone silicone: Dimethicone is the most used cosmetic silicone. It forms a breathable film that smooths the surface, slows water leaving skin, and gives the slip that makes a primer or cream feel silky. It is inert and does not penetrate.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Niacinamide active: Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
Methylpropanediol humectant: Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
Cetearyl Alcohol fatty alcohol: Cetearyl Alcohol is a waxy solid, not the drying kind of alcohol. It is a blend of cetyl and stearyl alcohols used to thicken a cream and keep oil and water from separating, and it softens skin as it does so.

94 more explained

Glyceryl Stearate emulsifier: Glyceryl Stearate is glycerin joined to stearic acid, and one of the most used emulsifiers in skincare. It holds oil and water together and thickens the result, and it softens skin at the same time.
Hydrogenated Vegetable Oil occlusive: Plant oil hardened by hydrogenation. It behaves as a soft solid, so it gives balms and sticks their body and slows water loss from the surface.
Polyglyceryl-3 Methylglucose Distearate emulsifier: Polyglyceryl-3 Methylglucose Distearate is a sugar-derived emulsifier known for a light, non-soapy feel. It builds gel-creams that do not read as rich.
Butyrospermum Parkii (Shea) Butter emollient: Shea Butter is the fat pressed from the shea nut, rich in oleic and stearic acids and unsaponifiable plant sterols. It is a heavy emollient and partial occlusive, which is why it sits in balms and night creams rather than in essences.
Dimethicone Crosspolymer silicone: Dimethicone Crosspolymer is silicone linked into a soft, springy network. It soaks up oil, blurs the look of texture, and gives the velvety feel of a primer.
Ammonium Acryloyldimethyltaurate/VP Copolymer thickener: This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
Sodium Polyacrylate thickener: Sodium Polyacrylate is a polymer that absorbs many times its weight in water. It thickens a formula and holds water in a gel against the skin.
Hydrogenated Lecithin emulsifier: Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
Carbomer thickener: Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
Xanthan Gum thickener: Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
Pentylene Glycol humectant: Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
Tromethamine pH adjuster: Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Adenosine active: Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
Palmitic Acid fatty acid: Palmitic Acid is a saturated fatty acid present in skin's own lipids. It thickens a formula, stabilises the emulsion and softens skin.
Stearic Acid fatty acid: Stearic Acid is a saturated fatty acid from plant fats, and one of the three lipid classes skin's own barrier is built from. In a formula it thickens, stabilises the emulsion and can be turned into a soap-style cleanser by adding a base.
Sodium Phytate chelator: Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
Cholesterol barrier lipid: Cholesterol is the third of the three lipids the outer layer of skin is built from, with ceramides and fatty acids. Formulas that carry all three are following the ratio skin itself holds.
Sodium Hyaluronate humectant: Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
Adenosine Triphosphate active: Adenosine Triphosphate is the molecule cells move energy around with. In a formula it is a conditioning nucleotide, related to the adenosine declared beside it.
Hydroxypropyl Cyclodextrin solvent: Hydroxypropyl Cyclodextrin is a ring-shaped sugar that traps an active molecule inside itself, keeping it stable and releasing it slowly. It is a delivery shell rather than an active.
Nicotinamide Adenine Dinucleotide active: Nicotinamide Adenine Dinucleotide, usually written NAD, is a coenzyme every living cell carries, built from vitamin B3. In a formula it is used as a conditioning active at very low levels.
Beta-Glucan polysaccharide: Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
Tocopherol antioxidant: Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
Palmitoyl Tripeptide-5 peptide: Palmitoyl Tripeptide-5 is a fatted three-amino-acid peptide used for the look of firmness and fine lines. The palmitoyl tail is what lets it cross an oily surface.
Saccharomyces/Copper Ferment ferment: Yeast grown in the presence of copper, so the mineral ends up bound inside the yeast. It is a way of delivering a trace mineral in an organic form.
Saccharomyces/Iron Ferment ferment: Yeast grown with iron so the mineral is carried inside the cells. It is used as a trace mineral source in an organic form.
Saccharomyces/Magnesium Ferment ferment: Yeast grown with magnesium so the mineral is bound into the ferment. It is used to supply a trace mineral in an organic form.
Saccharomyces/Silicon Ferment ferment: Yeast grown with silicon so the mineral is carried inside the cells. It is used as an organically bound source of silicon.
Saccharomyces/Zinc Ferment ferment: Yeast grown with zinc so the mineral ends up bound in the ferment. It is used to supply trace zinc in an organic form.
Thioctic Acid antioxidant: Thioctic Acid is alpha lipoic acid, an antioxidant that dissolves in both water and oil, which is unusual. It is yellow and carries a faint sulfur smell.
Leuconostoc/Radish Root Ferment Filtrate preservative: This is radish root fermented by Leuconostoc, the culture behind kimchi, then filtered clear. It carries natural antimicrobial peptides, so formulas use it in place of part of a conventional preservative.
Glutathione antioxidant: Glutathione is a small peptide the body uses as one of its main antioxidants. In skincare it is used as an antioxidant and for the look of dullness; it is unstable in water, so formulas that carry it are usually built around protecting it.
Tremella Fuciformis (Mushroom) Extract plant extract: Tremella Fuciformis is snow mushroom. Its polysaccharide holds even more water than hyaluronic acid for its weight, which is why it appears in hydrating Korean formulas as a plant alternative.
Haematococcus Pluvialis Oil antioxidant: An algae extract that is the main natural source of astaxanthin, the deep red carotenoid. It is used as a plant antioxidant and colours a formula orange-red.
Potassium Hydroxide pH adjuster: Potassium Hydroxide is a strong base used in traces to raise a formula to its target pH. In a soap-style cleanser it also converts fatty acids into the surfactant that does the cleansing.
Resveratrol antioxidant: Resveratrol is an antioxidant from grape skin and Japanese knotweed. It is used for the look of dullness and is often paired with ferulic acid, which keeps it stable.
Hesperidin Methyl Chalcone antioxidant: Hesperidin is the main flavonoid of citrus peel. It is used as a plant antioxidant and for the look of surface vessels.
Sorbitan Laurate emulsifier: Sorbitan Laurate is a light emulsifier and solubiliser, used to keep small amounts of oil or fragrance dissolved in a watery formula.
Astaxanthin antioxidant: Astaxanthin is a deep red antioxidant from microalgae, the pigment that makes salmon pink. It is oil soluble, colours a formula noticeably, and is used as an antioxidant.
Sodium Lactate humectant: Sodium Lactate is the salt of lactic acid and one of the components of skin's own natural moisturising factor. At the levels used here it is a humectant and buffer rather than an exfoliant.
Hydroxyethylcellulose thickener: Hydroxyethylcellulose is a cellulose thickener that builds a clear, smooth gel and holds the rest of the formula in suspension.
Acetyl Dipeptide-1 Cetyl Ester peptide: Acetyl Dipeptide-1 Cetyl Ester is a two-amino-acid peptide with a fatty cetyl tail attached, which lets it sit in the oil phase of a formula rather than only the water phase.
Dipeptide Diaminobutyroyl Benzylamide Diacetate peptide: This is a two-amino-acid peptide, sold as Syn-Ake, used for the look of expression lines. Its structure was modelled on a component of snake venom, though nothing of the venom itself is in it.
Heptasodium Hexacarboxymethyl Dipeptide-12 peptide: A two-amino-acid peptide with carboxymethyl groups added, which makes it strongly water soluble. It is used for the look of uneven tone.
Panthenol humectant: Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
Polysorbate 20 emulsifier: Polysorbate 20 is a solubiliser: it dissolves small amounts of oil or fragrance into a watery formula so nothing separates or floats.
Sodium Citrate pH adjuster: Sodium Citrate is the salt of citric acid, used as a buffer: it holds a formula at a steady pH rather than pushing it in one direction. It is also a mild chelator.
Dextran polysaccharide: Dextran is a branched sugar polymer made by fermenting sucrose. It holds water, thickens slightly, and is used as a carrier that keeps other water-soluble ingredients evenly spread.
Hexapeptide-2 peptide: Hexapeptide-2 is a six-amino-acid peptide used for the look of even tone rather than of lines, which puts it in the smaller group of peptides aimed at pigment.
Magnesium Chloride mineral: Magnesium Chloride is the magnesium salt that makes sea water taste bitter. In a formula it is a mineral salt in the water phase and helps set gum gels.
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate peptide: A synthetic peptide sold as Syn-Ake, built to mimic a peptide sequence found in snake venom. It is used for the look of expression lines.
Acetyl Tetrapeptide-5 peptide: Acetyl Tetrapeptide-5 is a four-amino-acid peptide used in eye products for the look of puffiness and crepiness.
Dipeptide-2 peptide: Dipeptide-2 is a two-amino-acid peptide used mainly in eye formulas, for the look of puffiness rather than of lines.
Potassium Sorbate preservative: Potassium Sorbate is a preservative that holds off yeast and mould in acidic formulas. It is almost always used with sodium benzoate, because neither covers the whole range of microbes alone.
Acetyl Hexapeptide-8 peptide: Acetyl Hexapeptide-8 is a six-amino-acid peptide used for the look of expression lines, particularly around the eyes. It is the peptide sold under the name Argireline and is water soluble and stable.
Citric Acid pH adjuster: Citric Acid is used in tiny amounts to bring a formula to the pH its actives need, not as an exfoliant at that level. It is an AHA, so at much higher concentrations it can also exfoliate.
Biotin vitamin: Biotin is vitamin B7. In skincare it is a conditioning vitamin, most often in hair and scalp formulas.
Palmitoyl Tetrapeptide-7 peptide: Palmitoyl Tetrapeptide-7 is a four-amino-acid peptide with a fatty tail, used for the look of fine lines. With palmitoyl tripeptide-1 it forms the pairing sold as Matrixyl 3000.
Biotinoyl Tripeptide-1 peptide: A three-amino-acid peptide joined to biotin, vitamin B7. It is the peptide most used in lash, brow and scalp formulas.
Acetyl Tetrapeptide-3 peptide: Acetyl Tetrapeptide-3 is a four-amino-acid peptide used for the look of density and firmness. It appears in scalp formulas as often as in facial ones.
Trifolium Pratense (Clover) Flower Extract plant extract: Red clover flower extract, carrying isoflavones. It is used as a conditioning plant extract.
Tocopheryl Acetate antioxidant: Tocopheryl Acetate is a stable vitamin E ester that skin converts to tocopherol. It is used as an antioxidant and a light emollient and holds up better than plain vitamin E in a formula.
Palmitoyl Tripeptide-8 peptide: A three-amino-acid peptide with a palmitic acid tail, which lets it sit in the oil phase. It is used for the look of reddened, reactive skin.
Dipeptide-4 peptide: Dipeptide-4 is a two-amino-acid peptide. It is water soluble and appears as one component of a multi-peptide blend rather than on its own.
Hexapeptide-11 peptide: Hexapeptide-11 is a yeast-derived six-amino-acid peptide used for the look of resilience and firmness.
Tripeptide-3 peptide: Tripeptide-3 is a three-amino-acid peptide used in multi-peptide blends. It turns up in hair and scalp formulas as often as in facial ones.
Sh-Decapeptide-7 peptide: A ten-amino-acid peptide made by fermentation. It is used as a conditioning peptide, usually within a blend.
Sh-Octapeptide-4 peptide: An eight-amino-acid peptide produced by fermentation. It is used as a conditioning peptide inside a wider peptide complex.
Palmitoyl Tripeptide-1 peptide: Palmitoyl Tripeptide-1 is a short peptide with a fatty tail added so it can travel through the oily outer layer of skin. It is used for the look of firmness and is almost always paired with palmitoyl tetrapeptide-7.
Ascorbic Acid Polypeptide antioxidant: Ascorbic Acid Polypeptide is vitamin C attached to a short protein chain to keep it stable in water. It is an antioxidant used for the look of dullness.
Hexapeptide-9 peptide: Hexapeptide-9 is a six-amino-acid peptide used for the look of firmness and elasticity. It is water soluble and appears in peptide blends rather than alone.
Oligopeptide-3 peptide: Oligopeptide-3 is another short synthetic peptide sequence. Numbered oligopeptides that sit next to each other on a label are separate sequences, not doses of one ingredient.
Palmitoyl Hexapeptide-12 peptide: Palmitoyl Hexapeptide-12 is a fatted six-amino-acid peptide used for the look of firmness, usually as part of a multi-peptide blend.
Tripeptide-1 peptide: Tripeptide-1 is the copper-free version of the classic three-amino-acid peptide. It is used for the look of firmness in formulas that avoid copper's blue tint.
Palmitoyl Pentapeptide-4 peptide: Palmitoyl Pentapeptide-4 is the five-amino-acid peptide originally sold as Matrixyl. It is used for the look of fine lines and is one of the longest-standing cosmetic peptides.
Ubiquinone antioxidant: Ubiquinone is coenzyme Q10, an antioxidant every cell uses in its own energy production. In a formula it is oil soluble, faintly yellow, and used for the look of tired, dull skin.
Copper Tripeptide-1 peptide: Copper Tripeptide-1 is three amino acids bound to a copper ion, and the classic firming peptide in cosmetic chemistry. It is blue in solution, which is often why a serum carrying it is tinted, and it is used for the look of firmness and fine lines.
Nicotinoyl Tripeptide-1 peptide: A three-amino-acid peptide joined to a vitamin B3 group. It is used as a conditioning peptide, most often in scalp and lash products.
Oligopeptide-1 peptide: Oligopeptide-1 is a short synthetic peptide. Oligo means the chain is short without the name fixing its length, which is why oligopeptides appear in blends where several sequences work together.
Asparagine amino acid: Asparagine is an amino acid used as a humectant and conditioner, almost always inside a wider amino acid blend rather than on its own.
Glutamine amino acid: Glutamine is the most abundant free amino acid in the body. In a formula it hydrates and conditions, usually as part of an amino acid blend.
Tryptophan amino acid: Tryptophan is an essential amino acid. On a label it is usually one of a set of amino acids added together as a conditioning, water-holding blend.
Oligopeptide-2 peptide: Oligopeptide-2 is a short synthetic peptide, water soluble like most of the unmodified oligopeptides. It is supplied as one component of a blend.
Sh-Oligopeptide-1 peptide: sh-Oligopeptide-1 is a peptide made by yeast fermentation rather than synthesis, which is what the sh prefix records. It is used for the look of firmness and skin recovery after irritation.
Sh-Oligopeptide-2 peptide: sh-Oligopeptide-2 is a second fermentation-produced peptide, used alongside sh-oligopeptide-1 for the look of firmness.
Sh-Polypeptide-1 peptide: sh-Polypeptide-1 is a longer fermentation-produced peptide. It is used in formulas built around the look of resilience and recovery.
Sh-Polypeptide-22 peptide: sh-Polypeptide-22 is another fermentation-produced peptide of the sh family, used in multi-peptide serums rather than on its own.
Sh-Polypeptide-3 peptide: sh-Polypeptide-3 is a peptide made by fermentation rather than by chemical synthesis, which is what the sh prefix records. Polypeptide means a longer chain than a tri or hexapeptide.
Acetyl Octapeptide-3 peptide: Acetyl Octapeptide-3 is an eight-amino-acid peptide used for the look of expression lines. It is usually paired with acetyl hexapeptide-8 rather than used alone.
Acetyl Tetrapeptide-2 peptide: Acetyl Tetrapeptide-2 is a four-amino-acid peptide used for the look of firmness, particularly in eye and neck formulas.
Acetyl Tetrapeptide-9 peptide: Acetyl Tetrapeptide-9 is a four-amino-acid peptide used for the look of firmness and density. It is most often supplied alongside acetyl tetrapeptide-11.
Carnosine antioxidant: Carnosine is a small peptide of two amino acids that acts as an antioxidant, particularly against the sugar-driven damage formulators call glycation. It is used for the look of dull, sallow skin.
Nonapeptide-1 peptide: Nonapeptide-1 is a nine-amino-acid peptide used for the look of uneven tone rather than for firmness, which makes it unusual among cosmetic peptides.

How it works

The panel on this essence names 48 forms of peptide rather than one: Palmitoyl Tripeptide-5, Capryloyl Dipeptide-17, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Heptasodium Hexacarboxymethyl Dipeptide-12, Hexapeptide-2, Acetyl Tetrapeptide-5, Dipeptide-2, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tetrapeptide-7, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Palmitoyl Tripeptide-8, Dipeptide-4, Hexapeptide-11, Pentapeptide-18, Tripeptide-3, Sh-Decapeptide-7, Sh-Octapeptide-4, Palmitoyl Tripeptide-1, Ascorbic Acid Polypeptide, Hexapeptide-9, Oligopeptide-3, Palmitoyl Hexapeptide-12, Tripeptide-1, Palmitoyl Pentapeptide-4, Copper Tripeptide-1, Caffeoyl Tripeptide-1, Caffeoyl Sh-Octapeptide-4, Galloyl Pentapeptide-33, Kojyl Carboxy Dipeptide-23, Nicotinoyl Tripeptide-1, Octapeptide-7, Oligopeptide-1, Sh-Decapeptide-9, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Oligopeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Sh-Polypeptide-3, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-9, Nonapeptide-1. Palmitoyl Tripeptide-5 is a fatted three-amino-acid peptide used for the look of firmness and fine lines. The palmitoyl tail is what lets it cross an oily surface. On this panel it sits alongside Niacinamide, Hydrogenated Vegetable Oil and Adenosine. Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.

How to use

Use it as the essence step, AM and PM, after toner and before serum, giving it a moment to settle before the next step.

Worth knowing

Patch test on the inner arm first if trying a new brand's formula for the first time.
Stop use and check the ingredient list against any known sensitivities before continuing.

Complete the routine

This itemNumbuzin No.9 NMN BIO Lifting-Sil Essence 50ml$45.00
Prep after cleansing, before the treatment stepnumbuzin No.3 Bifida Bakuchiol Exfoliating Toner Pads 190ml/70ea$40.00
The treatment step of this routinenumbuzin No.3 Bifida Bakuchiol Zero Pore Serum 30ml$47.50

Total for 3 items$132.50

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numbuzin No.9 NMN BIO Lifting-Sil Essence 50ml

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Numbuzin, Korean-market original

The Korean-market essence built around Glycerin, from Numbuzin, sourced for the Korean market and reviewed before it ever reaches this page.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

Peptides can be anti-inflammatory, and chronic inflammation damages the tissue in your skin.
Wilma Bergfeld, MDDermatologist, Cleveland Clinic
In skin, different peptides can encourage different things, from collagen formation to a reduction in inflammation to helping with wound healing depending on their structure.
Whitney Hovenic, MDDouble board-certified dermatologist and Mohs surgeon, Women's Health

1 more professional perspective

Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.
Ashlyn YankeAesthetician, Cleveland Clinic