Where does this cream go in my routine?

As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Sodium DNA and not three changes at once.

What else is on the list besides Sodium DNA?

Niacinamide, Adenosine and Madecassoside. The order they are printed in on this cream's panel is the order on the box, so you can see where Sodium DNA sits relative to them. Further down the same panel: Asiaticoside, Hydrolyzed Collagen and Melia Azadirachta Leaf Extract.

Anua

PDRN Hyaluronic Acid 100 Moisturising Cream

Name: Anua PDRN Hyaluronic Acid 100 Moisturising Cream
Brand: Anua
Price: 24.99 USD
Availability: OutOfStock

Squalane sits second and Hydrolyzed Collagen fourth, with Niacinamide eighth and Sodium DNA tenth, in a bouncy gel-cream that finishes dewy rather than greasy. The last step of a routine, morning or night.

Reviewed by Nurcan Saglam, licensed dermo-cosmetic expert (Paris)

No reviews yet

$24.99

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: Dehydrated skinSensitive skinSkin that has lost bounce

Helps with: Shoppers looking for Sodium DNA in a creamRoutines that want Sodium DNA and Niacinamide in one stepFilling the cream step with a Korean-market formula

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Key benefits

Sodium DNA, the active this cream is built around
Niacinamide, Adenosine, Madecassoside and Asiaticoside on the same list, actives
Hydrolyzed Collagen and Melia Azadirachta Leaf Extract further down the same list
Coccinia Indica Fruit Extract and Solanum Melongena (Eggplant) Fruit Extract further down the same list
Sodium DNA named tenth on the manufacturer list printed on this page

Key actives

8Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. The panel names it eighth on this cream's list, beside Sodium DNA.

All products with Niacinamide

10Sodium DNAactive

Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to. It is the entry this cream is named after, and the list carries it.

All products with PDRN

43Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. The panel names it forty-third on this cream's list, beside Sodium DNA.

All products with Adenosine

46Madecassosideactive

Madecassoside is the centella triterpene most associated with the look of redness, and the one brands lead with in cica products. It is water soluble and stable, so it appears in essences as readily as in creams. The panel names it forty-sixth on this cream's list, beside Sodium DNA.

All products with Madecassoside

47Asiaticosideactive

Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised. The panel names it forty-seventh on this cream's list, beside Sodium DNA.

All products with Asiaticoside

Inside the formula

Ingredients declared

No fragrance

on the list

8Niacinamide43Adenosine46Madecassoside

8Niacinamide
43Adenosine
46Madecassoside

Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.

1 of 5

Anua PDRN Hyaluronic Acid 100 Moisturising Cream

45 of 48 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Squalane emollient: Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Hydrolyzed Collagen protein: Hydrolyzed Collagen is collagen broken into fragments small enough to dissolve in water. It cannot become collagen in skin; what it does is hold water at the surface and leave a smooth, conditioned film.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Methylpropanediol humectant: Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Niacinamide active: Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Sodium DNA active: Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to.
Pentylene Glycol humectant: Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
PVM/MA Copolymer film former: PVM/MA Copolymer is a film-forming polymer used to hold a formula in place and, in a mask, to give the peel-off film its strength.

33 more explained

Carbomer thickener: Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
Diphenylsiloxy Phenyl Trimethicone silicone: Diphenylsiloxy Phenyl Trimethicone is a high-shine silicone used where a formula needs gloss without stickiness.
PCA Dimethicone silicone: A silicone carrying a PCA group, the same humectant skin makes for itself. It gives silicone slip and holds a little water at once.
Behenyl Alcohol fatty alcohol: Behenyl Alcohol is a long-chain fatty alcohol used to thicken and stabilise a cream. It gives a richer, more velvety body than cetyl alcohol.
Ammonium Acryloyldimethyltaurate/VP Copolymer thickener: This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
Propanediol humectant: Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
C14-22 Alcohols fatty alcohol: C14-22 Alcohols is a declaration for a mixture of long-chain fatty alcohols. They thicken a cream and hold the emulsion together.
C12-20 Alkyl Glucoside emulsifier: C12-20 Alkyl Glucoside is a sugar-derived emulsifier used in mild, plant-based cream bases.
Diglycerin humectant: Diglycerin is two glycerin units joined together. It holds water like glycerin but feels less tacky, so it is used where a formula needs hydration without drag.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer thickener: This is the thickener behind most gel-cream textures. It builds a soft, bouncy gel that collapses to a light fluid as it is rubbed in.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener: This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
C12-13 Alketh-9 emulsifier: C12-13 Alketh-9 is a solubiliser used to disperse oil-soluble ingredients evenly in a watery formula.
Melia Azadirachta Leaf Extract plant extract: Melia Azadirachta is neem. Its leaf and flower extracts are long-standing Ayurvedic ingredients, and Korean formulas use them in products aimed at the look of congested, blemish-prone skin.
Coccinia Indica Fruit Extract plant extract: Coccinia Indica is ivy gourd. Its fruit extract is used as a conditioning, hydrating plant extract in Korean formulas.
Solanum Melongena (Eggplant) Fruit Extract plant extract: Eggplant Fruit Extract carries nasunin, the antioxidant pigment in aubergine skin. It is used as an antioxidant plant extract.
Aloe Barbadensis Flower Extract plant extract: Aloe Flower Extract comes from the flower rather than the leaf gel. It is used as a conditioning plant extract.
Ocimum Sanctum Leaf Extract plant extract: Ocimum Sanctum is holy basil, or tulsi. Its leaf extract carries plant antioxidants and is used in formulas built for the look of stressed, reactive skin.
Corallina Officinalis Extract plant extract: Corallina Officinalis is coral seaweed, which holds calcium and magnesium in its structure. Its extract is used as a mineral-rich conditioning ingredient.
Curcuma Longa (Turmeric) Root Extract plant extract: Turmeric Root Extract carries curcuminoids, well studied plant antioxidants. It is used for the look of dullness and uneven tone, and it tints a formula faintly yellow.
Sodium Hyaluronate humectant: Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
Dimethylsilanol Hyaluronate humectant: Dimethylsilanol Hyaluronate is hyaluronic acid joined to a silicon-based group. It hydrates and leaves a smoother, silkier finish than hyaluronic acid alone.
Hydrolyzed Hyaluronic Acid humectant: Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
Potassium Hyaluronate humectant: Potassium Hyaluronate is another salt of hyaluronic acid, used for the same reason as the sodium form: it dissolves easily and holds a large amount of water in the outer layer of skin.
Hyaluronic Acid humectant: Hyaluronic Acid is a sugar chain the body already makes, and one gram of it can hold several litres of water. In a formula it is a humectant that pulls water to the surface of skin and holds it in a film, which is what makes skin look plumper while it is there.
Hydroxypropyltrimonium Hyaluronate humectant: Hydroxypropyltrimonium Hyaluronate carries a positive charge, and skin carries a slight negative one, so it is attracted to the surface and stays through rinsing. It is the hyaluronic used where a formula gets washed off.
Sodium Hyaluronate Crosspolymer humectant: Sodium Hyaluronate Crosspolymer is hyaluronic acid linked into a mesh. It holds water in a soft gel on the surface rather than sinking in, and it releases that water slowly through the day.
Sodium Acetylated Hyaluronate humectant: Sodium Acetylated Hyaluronate is hyaluronic acid modified to be part oil-loving, so it clings to skin instead of rinsing away. Formulators call it the one that stays put.
Adenosine active: Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
Sodium Phytate chelator: Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
Aminomethyl Propanediol pH adjuster: An alkaline compound used to raise the pH of a formula, most often so an acrylate thickener will swell into a gel.
Madecassoside active: Madecassoside is the centella triterpene most associated with the look of redness, and the one brands lead with in cica products. It is water soluble and stable, so it appears in essences as readily as in creams.
Asiaticoside active: Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised.
Centella Asiatica Leaf Extract plant extract: Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.

How it works

The PDRN Hyaluronic Acid 100 Moisturising Cream is a cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Sodium DNA, named tenth on its own ingredient list. The same list carries Niacinamide, Adenosine and Madecassoside, so the active is not the only thing on it worth naming. How much of the Sodium DNA stays on the skin, and for how long, is decided by the cream format rather than by the list alone. Anua sells this Sodium DNA cream in Korea, and this is that version.

How to use

Use the PDRN Hyaluronic Acid 100 Moisturising Cream as the last skincare step, morning and evening, over serum.
A generous fingertip for the whole face. It spreads further than a cream, so start with less than you think.
Serum first, this second. In the morning it is the layer sunscreen goes over, so give it a minute to settle first.
Twice a day, every day. Do not layer it under a heavier cream to get more out of it; two lids in one routine only slow the first one down.

Worth knowing

Patch test this cream on a small area and wait a day before using it more widely, especially with Sodium DNA on the list.
Introduce this cream on its own for the first week, so anything your skin does is traceable to the Sodium DNA rather than to three changes at once.

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Anua PDRN Hyaluronic Acid 100 Moisturising Cream

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Anua, Korean-market original

The Original Korean Formula cream from Anua, formulated with Sodium DNA and Niacinamide, shipped from California or direct from Korea.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Anua uses a holographic QR seal that only the HiddenTag app can read. Install HiddenTag from your phone’s app store and scan the seal on the box. A camera app alone will not resolve it.

Source: Anua packaging, HiddenTag scheme

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

Centella can make your skin appear more hydrated, plumper and healthier.
Samantha Stein, PA-CDermatology physician assistant, Cleveland Clinic
It's still a very new ingredient in the field of regenerative medicine.
Catherine ChangBeverly Hills board-certified plastic and reconstructive surgeon, Harper's Bazaar

1 more professional perspective

Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.
Ashlyn YankeAesthetician, Cleveland Clinic