Where does this cream go in my routine?

As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Allantoin and not three changes at once.

Is this the Korean-market cream or a US version?

The Korean-market one, Allantoin and all. We match this cream to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.

What else is on the list besides Allantoin?

Adenosine, Lactobacillus Ferment and Saccharomyces Ferment Filtrate. The order they are printed in on this cream's panel is the order on the box, so you can see where Allantoin sits relative to them. Further down the same panel: Galactomyces Ferment Filtrate, Bifida Ferment Lysate and Tocopherol.

AXIS-Y

Biome Ultimate Indulging Cream 55ml

Name: AXIS-Y Biome Ultimate Indulging Cream 55ml
Brand: AXIS-Y
SKU: 7708168361
Price: 70.0 USD
Availability: InStock

Biome Ultimate Indulging Cream 55ml is AXIS-Y's cushioned moisturizer, built around Squalane and Allantoin for moisture loss through the day, formulated with a fermentation-forward Biome base rather than a single headline active.

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$70.00

55 ml

$127.27 per 100 ml

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: Dry skinCompromised barrierDehydrated skinSensitive skin

Helps with: Shoppers looking for Allantoin in a creamRoutines that want Allantoin and Adenosine in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Allantoin cream sold on Korean shelves

One-time purchase

$70.00

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$63.00

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How it works

The Biome Ultimate Indulging Cream is a 55ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Allantoin, named twelfth on its own ingredient list. The same list carries Adenosine, Lactobacillus Ferment and Saccharomyces Ferment Filtrate, so the active is not the only thing on it worth naming. How much of the Allantoin stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream AXIS-Y sells in Korea, Allantoin and all.

Key benefits

Allantoin, the active this cream is built around
Adenosine on the same list, an active
Lactobacillus Ferment, Saccharomyces Ferment Filtrate and Galactomyces Ferment Filtrate on the same list, ferments
Bifida Ferment Lysate and Tocopherol further down the same list
Ceramide NP and Ceramide AP further down the same list
Allantoin named twelfth on the manufacturer list printed on this page

Inside the formula

Ingredients declared

No fragrance

on the list

1 of 4

54 of 56 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Betaine humectant: Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
Methylpropanediol humectant: Methylpropanediol is a small glycol used to hydrate and to help water-soluble actives penetrate the outer layer of skin more evenly. It leaves almost no tack, which suits watery textures.
Cyclohexasiloxane silicone: Cyclohexasiloxane is a volatile silicone used for a light, fast-spreading feel that leaves nothing behind.
Pentaerythrityl Distearate emollient: Pentaerythrityl Distearate is a firm wax ester. It thickens an oil phase and helps a stick or balm hold its shape.
Squalane emollient: Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
Dicaprylyl Ether emollient: Dicaprylyl Ether is a very light emollient used to make a formula spread quickly and feel dry rather than oily.
Caprylic/Capric Triglyceride emollient: Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
Cetearyl Alcohol fatty alcohol: Cetearyl Alcohol is a waxy solid, not the drying kind of alcohol. It is a blend of cetyl and stearyl alcohols used to thicken a cream and keep oil and water from separating, and it softens skin as it does so.
Cetearyl Glucoside emulsifier: Cetearyl Glucoside is a sugar-derived emulsifier used to hold oil and water together in creams with a light finish.
Allantoin active: Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin.

42 more explained

Adenosine active: Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
Ceramide NP barrier lipid: Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
Ceramide AP barrier lipid: Ceramide AP is a second cosmetic ceramide, distinguished by an extra hydroxyl group. Formulas that name several ceramides are copying the mix skin actually holds rather than relying on one.
Hydrogenated Lecithin emulsifier: Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
Glycosphingolipids barrier lipid: Glycosphingolipids are ceramide-family lipids carrying a sugar group. They belong to the same lipid structure between skin cells and are used to make a formula feel more conditioning.
Tetraacetylphytosphingosine barrier lipid: A protected form of phytosphingosine, one of the sphingoid bases that ceramides are built from. The acetyl groups are what keep it stable in a formula.
Stearic Acid fatty acid: Stearic Acid is a saturated fatty acid from plant fats, and one of the three lipid classes skin's own barrier is built from. In a formula it thickens, stabilises the emulsion and can be turned into a soap-style cleanser by adding a base.
Cholesterol barrier lipid: Cholesterol is the third of the three lipids the outer layer of skin is built from, with ceramides and fatty acids. Formulas that carry all three are following the ratio skin itself holds.
Mangifera Indica (Mango) Seed Butter emollient: Mango seed butter, pressed from the kernel. It is a soft solid at room temperature and melts on skin, so it is used where a formula needs richness without the waxiness of shea.
Butyrospermum Parkii (Shea) Butter emollient: Shea Butter is the fat pressed from the shea nut, rich in oleic and stearic acids and unsaponifiable plant sterols. It is a heavy emollient and partial occlusive, which is why it sits in balms and night creams rather than in essences.
Beta-Glucan polysaccharide: Beta-Glucan is a polysaccharide from oats or yeast. It holds a large amount of water, forms a soothing film, and is one of the ingredients formulators reach for in products aimed at reactive skin.
Hydrolyzed Hyaluronic Acid humectant: Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
Sodium Hyaluronate humectant: Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Lactobacillus Ferment ferment: Lactobacillus Ferment is the liquid left after lactobacillus bacteria have fermented a plant or milk substrate. It carries the small molecules the fermentation produced, including lactic acid and amino acids, and is used for the look of dull, uneven skin.
Saccharomyces Ferment Filtrate ferment: Saccharomyces Ferment Filtrate is a brewers yeast ferment filtered clear. It supplies amino acids, B vitamins and sugars, and it is one of the ferments the Korean essence category was built on.
Galactomyces Ferment Filtrate ferment: Galactomyces Ferment Filtrate is a yeast ferment filtered clear, the ingredient that made the Korean and Japanese essence category. It carries amino acids, vitamins and organic acids and is used for the look of dullness and rough texture.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Theobroma Cacao (Cocoa) Seed Extract plant extract: Cocoa Extract carries polyphenols and a little caffeine. It is used as an antioxidant plant extract and gives a faint warm tint.
Bifida Ferment Lysate ferment: Bifida Ferment Lysate is a bifidobacteria ferment with the cells broken open. It is the ingredient behind the first-essence category and is used for the look of tired, reactive skin.
Artemisia Princeps Leaf Extract plant extract: Artemisia Princeps is Korean mugwort, one of the country's oldest skincare and bathing plants. Its leaf extract is used for the look of reddened, reactive skin, and it is the ingredient behind the mugwort category.
Centella Asiatica Extract plant extract: Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
Laminaria Japonica Extract plant extract: Laminaria Japonica is kombu kelp. Its extract carries alginates, minerals and iodine, and it is used as a hydrating, mineral-rich ingredient.
Eclipta Prostrata Leaf Extract plant extract: Eclipta Prostrata is false daisy, long used in Ayurvedic and East Asian practice. Its extract is used as a conditioning plant extract, most often in scalp and hair formulas.
Fructooligosaccharides humectant: Fructooligosaccharides are short fructose chains used as humectants and as food for the skin's own resident microbes.
Sodium Polyacrylate thickener: Sodium Polyacrylate is a polymer that absorbs many times its weight in water. It thickens a formula and holds water in a gel against the skin.
Sodium Stearoyl Glutamate emulsifier: Sodium Stearoyl Glutamate is an amino-acid-derived emulsifier. It holds oil and water together and is mild enough for formulas built for reactive skin.
Dipropylene Glycol humectant: Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
Hydroxyacetophenone preservative booster: Hydroxyacetophenone is an antioxidant that also strengthens a preservative system, so a formula needs less traditional preservative. Korean formulas pair it with 1,2-hexanediol constantly.
Disodium EDTA chelator: EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
Dextrin thickener: Dextrin is a starch fragment used to thicken and to give a formula a light, powdery finish. It is also a common carrier for powdered extracts.
Glyceryl Stearate emulsifier: Glyceryl Stearate is glycerin joined to stearic acid, and one of the most used emulsifiers in skincare. It holds oil and water together and thickens the result, and it softens skin at the same time.
Pentylene Glycol humectant: Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Tocopherol antioxidant: Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
Caprylyl Glycol preservative booster: Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
Xanthan Gum thickener: Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
Juniperus Virginiana Oil fragrance: Virginian cedarwood oil, a soft woody essential oil. Like every essential oil it carries aromatic terpenes and is a fragrance ingredient.
Cedrus Atlantica Bark Oil fragrance component: Atlas Cedar Bark Oil is a woody essential oil used to scent a formula.
Amyris Balsamifera Bark Oil fragrance component: Amyris oil, distilled from the wood of a Caribbean tree and often sold as West Indian sandalwood. It carries a soft woody scent and is used as a fragrance base note.
Copaifera Officinalis (Balsam Copaiba) Resin emollient: Copaiba Resin is a fragrant tree resin used as a thick emollient and a natural scent component in balms.
Pogostemon Cablin Oil fragrance component: Patchouli oil, steam distilled from the leaves. It is one of the heaviest, longest lasting aromatic oils and is used to scent a formula and to hold lighter notes in place.

How to use

Apply it last, after your toner, essence and any serum have gone on.
Warm a small amount between your fingers first, then press it over slightly damp skin.
Bring it down over the neck in the same pass, since a routine usually runs out at the jaw.
Do not use a thick layer under makeup in the morning, because a rich cream will move a foundation around.

Worth knowing

Patch test this cream on a small area and wait a day before using it more widely, especially with Allantoin on the list.
Introduce this cream on its own for the first week, so anything your skin does is traceable to the Allantoin rather than to three changes at once.

Complete the routine

This itemAXIS-Y Biome Ultimate Indulging Cream 55ml$70.00
The treatment step of this routineAXIS-Y Artichoke Intensive Skin Barrier Ampoule$16.46
Cleanse first, so the next step meets bare skinAXIS-Y Quinoa One Step Balanced Gel Cleanser 180ml$32.50

Total for 3 items$118.96

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AXIS-Y Biome Ultimate Indulging Cream 55ml

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AXIS-Y, Korean-market original

The Original Korean Formula cream from AXIS-Y, 55ml formulated with Allantoin and Adenosine, shipped from California or direct from Korea.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about skin care, quoted from the medical sources linked beside each.

Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic
Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic