Dr.Althea
Dr. Althea 345 Relief Cream$23.52Centellian24
Madeca Acnience Cream 50ml
Centella asiatica extract opens this 50 ml Centellian24 cream's list ahead of both glycerin and water, with niacinamide eighth and tea tree leaf oil and extract behind it. A light cream that sets matte, for congested skin, kept to the evening and off broken skin.
No reviews yet50ml
$51.98 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Dry skinCompromised barrierDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Niacinamide in a creamRoutines that want Niacinamide and Adenosine in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Niacinamide cream sold on Korean shelves
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Dr. Althea 345 Relief CreamDr.Althea
$23.52
$37.50
$16.46
- 30-day returns
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How it works
The Madeca Acnience Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Niacinamide, named eighth on its own ingredient list. The same list carries Adenosine, Allantoin and Dipotassium Glycyrrhizate, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream Centellian24 sells in Korea, Niacinamide and all.
Key benefits
- Niacinamide, the active this cream is built around
- Adenosine, Allantoin, Dipotassium Glycyrrhizate and Asiaticoside on the same list, actives
- Madecassic Acid and Asiatic Acid further down the same list
- Saccharomyces Ferment and Tocopherol further down the same list
- Niacinamide named eighth on the manufacturer list printed on this page
- The Korean-market release of this cream, confirmed against its Korean barcode
Inside the formula
Inside the formula
Centellian24 Madeca Acnience Cream 50ml
Where does this cream go in my routine?
As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Niacinamide and not three changes at once.
Is this the Korean-market cream or a US version?
The Korean-market one, Niacinamide and all. We match this cream to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
Does this cream contain fragrance?
Yes. The ingredient list names Citronellol, Limonene and Linalool. They sit on the panel printed on this page, so you can read the position for yourself before you buy. If fragrance components are something you avoid, this cream is not the one.
What else is on the list besides Niacinamide?
Adenosine, Allantoin and Dipotassium Glycyrrhizate. The order they are printed in on this cream's panel is the order on the box, so you can see where Niacinamide sits relative to them. Further down the same panel: Asiaticoside, Madecassic Acid and Asiatic Acid.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (64): Centella Asiatica Extract, Glycerin, Dipropylene Glycol, Water, Butylene Glycol, Diisostearyl Malate, Isononyl Isononanoate, Niacinamide, Polyglyceryl-3 Methylglucose Distearate, 1,2-Hexanediol, Pentylene Glycol, Hydrogenated Vegetable Oil, Helianthus Annuus (Sunflower) Seed Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Melaleuca Alternifolia (Tea Tree) Extract, Melaleuca Alternifolia (Tea Tree) Flower/Leaf/Stem Extract, Olea Europaea (Olive) Fruit Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Pelargonium Graveolens Flower Oil, Cryptomeria Japonica Leaf Extract, Nelumbo Nucifera Leaf Extract, Saccharomyces Ferment, Cananga Odorata Flower Oil, Cedrus Atlantica Bark Oil, Lavandula Angustifolia (Lavender) Oil, Rosa Damascena Flower Oil, Citrus Aurantium Dulcis (Orange) Oil, Copaifera Officinalis (Balsam Copaiba) Resin, Jasminum Officinale (Jasmine) Flower Water, Artemisia Absinthium Extract, Citrus Grandis (Grapefruit) Peel Oil, Rose Flower Oil, Ferula Galbaniflua (Galbanum) Resin Oil, Thuja Occidentalis Leaf Oil, Pinus Pinaster Bark Extract, Diglycerin, Octyldodecanol, Pentaerythrityl Tetraethylhexanoate, Cyclodextrin, Caprylyl Methicone, Vinyl Dimethicone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sorbitol, Tromethamine, Polyglyceryl-3 Diisostearate, Glyceryl Acrylate/Acrylic Acid Copolymer, Adenosine, Ethylhexylglycerin, Sodium Phytate, Ceteareth-20, Allantoin, Dipotassium Glycyrrhizate, Panthenol, Hydrogenated Lecithin, Asiaticoside, Madecassic Acid, Lecithin, Asiatic Acid, Tocopherol, Totarol, Carbomer, Limonene, Linalool, Citronellol
Ingredient list read from centellian24.com on 18 August 2026.
63 of 64 explained
- Centella Asiatica Extract plant extract
- Centella Asiatica is the plant behind the whole cica category, sold as gotu kola or Madagascar centella. Its extract is the anchor of Korean formulas built for easily reddened skin, and its work is done by four triterpenes: asiaticoside, madecassoside, asiatic acid and madecassic acid.
- Glycerin humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- Dipropylene Glycol humectant
- Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
- Water solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- Butylene Glycol humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- Diisostearyl Malate emollient
- Diisostearyl Malate is a thick, glossy ester used to hold pigment in suspension and give a cushioned shine. It is the standard emollient in lip products.
- Isononyl Isononanoate emollient
- Isononyl Isononanoate is a branched ester used as a dry emollient. It spreads far for its weight and leaves almost no residue, which is why it appears in formulas that have to feel weightless.
- Niacinamide active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- Polyglyceryl-3 Methylglucose Distearate emulsifier
- Polyglyceryl-3 Methylglucose Distearate is a sugar-derived emulsifier known for a light, non-soapy feel. It builds gel-creams that do not read as rich.
- 1,2-Hexanediol humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- Pentylene Glycol humectant
- Pentylene Glycol hydrates and, like the other longer-chain glycols, makes a formula less hospitable to microbes so the preservative system can be lighter. It also improves how evenly a product spreads.
- Hydrogenated Vegetable Oil occlusive
- Plant oil hardened by hydrogenation. It behaves as a soft solid, so it gives balms and sticks their body and slows water loss from the surface.
51 more explained
- Helianthus Annuus (Sunflower) Seed Oil emollient
- Sunflower Seed Oil is high in linoleic acid, the fatty acid dry and blemish-prone skin is often short of. It is a light, non-fragrant emollient and one of the better tolerated plant oils.
- Melaleuca Alternifolia (Tea Tree) Leaf Oil fragrance component
- Tea Tree Leaf Oil is an essential oil from an Australian shrub, carrying terpinen-4-ol. Korean formulas use it in products aimed at blemish-prone skin; it is potent, aromatic, and one of the essential oils most likely to bother reactive skin.
- Melaleuca Alternifolia (Tea Tree) Extract plant extract
- Tea Tree Leaf Extract is the water-based extract rather than the essential oil, so it is far milder and much less aromatic. It is used in formulas for blemish-prone skin.
- Melaleuca Alternifolia (Tea Tree) Flower/Leaf/Stem Extract plant extract
- Tea tree extract taken from the whole plant above ground, rather than the distilled oil. It is much gentler than the oil and is used for the look of congested skin.
- Olea Europaea (Olive) Fruit Oil emollient
- Olive Fruit Oil is high in oleic acid and plant sterols. It is a rich emollient that suits dry skin and is heavy enough that blemish-prone skin often does not get on with it.
- Citrus Aurantium Bergamia (Bergamot) Fruit Oil fragrance component
- Bergamot Fruit Oil is a citrus essential oil and the top note of eau de cologne. It scents a formula; citrus oils are the aromatic class most likely to bother reactive skin.
- Pelargonium Graveolens Flower Oil fragrance component
- Pelargonium Graveolens is rose geranium. Its flower oil is an essential oil used to scent a formula, carrying citronellol and geraniol.
- Cryptomeria Japonica Leaf Extract plant extract
- Cryptomeria Japonica is Japanese cedar. Its leaf extract is used as an aromatic antioxidant plant extract.
- Nelumbo Nucifera Leaf Extract plant extract
- Nelumbo Nucifera is the sacred lotus. Its leaf extract carries flavonoids and is used as a conditioning antioxidant extract.
- Saccharomyces Ferment ferment
- Saccharomyces Ferment is a brewer's yeast ferment. It supplies amino acids, sugars and B vitamins and is used as a conditioning, hydrating ferment.
- Cananga Odorata Flower Oil fragrance
- Ylang ylang oil, a heavy sweet floral essential oil. It is among the most commonly declared natural fragrance materials.
- Cedrus Atlantica Bark Oil fragrance component
- Atlas Cedar Bark Oil is a woody essential oil used to scent a formula.
- Lavandula Angustifolia (Lavender) Oil fragrance component
- Lavender Oil is an essential oil carrying linalool and linalyl acetate. It scents a formula, and linalool is one of the fragrance components EU labelling requires to be named separately.
- Rosa Damascena Flower Oil fragrance component
- Rosa Damascena Flower Oil is rose essential oil, one of the most expensive materials in perfumery. It scents a formula, and like every essential oil it is a class reactive skin often does not tolerate.
- Citrus Aurantium Dulcis (Orange) Oil fragrance component
- Sweet Orange Peel Oil is a citrus essential oil carrying limonene. It scents a formula, and limonene is one of the components EU labelling names separately.
- Copaifera Officinalis (Balsam Copaiba) Resin emollient
- Copaiba Resin is a fragrant tree resin used as a thick emollient and a natural scent component in balms.
- Jasminum Officinale (Jasmine) Flower Water plant extract
- Jasmine distillate, used in place of plain water as a base. A flower water is far more dilute than the oil, so it sets the base and carries a faint scent.
- Artemisia Absinthium Extract plant extract
- Artemisia Absinthium is wormwood, another mugwort relative. Its extract carries aromatic plant compounds and is used as a conditioning extract.
- Citrus Grandis (Grapefruit) Peel Oil fragrance component
- Grapefruit Peel Oil is a citrus essential oil rich in limonene. It scents a formula and belongs to the aromatic class reactive skin often avoids.
- Ferula Galbaniflua (Galbanum) Resin Oil fragrance component
- Galbanum Resin Oil is a green, resinous essential oil used in perfumery to scent a formula.
- Thuja Occidentalis Leaf Oil fragrance
- Northern white cedar leaf oil, a sharp coniferous essential oil used at very low levels for scent.
- Pinus Pinaster Bark Extract plant extract
- Maritime pine bark extract, the source of the proanthocyanidins sold under the pine bark name. It is used as a plant antioxidant.
- Diglycerin humectant
- Diglycerin is two glycerin units joined together. It holds water like glycerin but feels less tacky, so it is used where a formula needs hydration without drag.
- Octyldodecanol emollient
- Octyldodecanol is a branched fatty alcohol used as an emollient and as a solvent for pigments and mineral powders. It thickens slightly and leaves a soft finish.
- Pentaerythrityl Tetraethylhexanoate emollient
- Pentaerythrityl Tetraethylhexanoate is a light ester emollient that gives a dry, silky finish and disperses pigment evenly.
- Cyclodextrin solvent
- A ring-shaped sugar with a hollow centre. Formulas use it to hold an oil, a fragrance or an unstable active inside the ring, which keeps it stable and slows its release.
- Caprylyl Methicone silicone
- Caprylyl Methicone is a silicone with a fatty tail, so it mixes with plant oils as well as with silicones. It gives a dry slip and helps disperse powders.
- Vinyl Dimethicone silicone
- Vinyl Dimethicone is a silicone used as a building block of the crosspolymer gels that give a formula its soft, blurring feel.
- Ammonium Acryloyldimethyltaurate/VP Copolymer thickener
- This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
- Sorbitol humectant
- Sorbitol is a sugar alcohol used as a humectant. It hydrates like glycerin with a smoother, less sticky finish, and it adds a little body to watery textures.
- Tromethamine pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
- Polyglyceryl-3 Diisostearate emulsifier
- Polyglyceryl-3 Diisostearate is a plant-derived emulsifier for water-in-oil formulas. It appears in cleansing balms and rich creams built without PEGs.
- Glyceryl Acrylate/Acrylic Acid Copolymer film former
- This is a polymer that forms a moisture-holding film on the surface, usually supplied with glycerin and propylene glycol as a hydrating complex.
- Adenosine active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- Ethylhexylglycerin preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- Sodium Phytate chelator
- Sodium Phytate is a rice-derived chelator used in place of EDTA. It ties up trace metals so the formula stays stable and its colour and scent hold.
- Ceteareth-20 emulsifier
- An ethoxylated fatty alcohol that holds oil and water together in a cream. The number records how much ethylene oxide was added, which sets how water-loving it is.
- Allantoin active
- Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin.
- Dipotassium Glycyrrhizate active
- Dipotassium Glycyrrhizate is a water-soluble salt derived from licorice root. It is the licorice fraction Korean formulas use for the look of redness, and it is far more stable in water than the whole extract.
- Panthenol humectant
- Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
- Hydrogenated Lecithin emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- Asiaticoside active
- Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised.
- Madecassic Acid active
- Madecassic Acid is the fourth centella triterpene. A list that names all four is telling you the extract was standardised rather than simply pressed, which is the difference between a cica claim and a cica formula.
- Lecithin emulsifier
- Lecithin is a soy or sunflower-derived phospholipid, the same class of molecule cell membranes are built from. It emulsifies oil into water and is the basis of the liposomes formulators use to carry actives.
- Asiatic Acid active
- Asiatic Acid is the third of centella's four triterpenes and the aglycone form, meaning it has no attached sugar. It is oil soluble, so it turns up in cica creams and balms more than in watery layers.
- Tocopherol antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- Totarol preservative booster
- A compound from the heartwood of the New Zealand totara tree. It is antimicrobial, so a formula uses it to support the preservative system.
- Carbomer thickener
- Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
- Limonene fragrance component
- Limonene is the citrus-peel aromatic. It appears here because EU labelling requires 26 fragrance components to be named individually rather than hidden inside "fragrance", and it is one of them.
- Linalool fragrance component
- Linalool is a floral aromatic found in lavender, bergamot and coriander. It is one of the 26 fragrance components EU labelling requires to be declared by name.
- Citronellol fragrance component
- Citronellol is a rose-geranium aromatic and one of the 26 fragrance components EU labelling names individually.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8806109100656
- Made in
- Republic of Korea
- Volume
- 50ml
- Category
- Moisturizer
- Actives
- Adenosine, Allantoin, Centella Asiatica, Licorice Root, Niacinamide, Panthenol, Tea Tree
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Use it as the last step in the evening, over the whole face or only the congested areas.
- A thin layer is enough; a congested face does not want a heavy one.
- Press it in over damp skin rather than rubbing it into areas that are already sore.
- Every evening. Keep it off broken skin, and do not layer it with a scrub in the same routine.
Worth knowing
- Patch test this cream on a small area and wait a day before using it more widely, especially with Niacinamide on the list.
- This list names Citronellol, Limonene and Linalool, so skip it if fragrance components are something you avoid.
Reviews
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Centellian24 Madeca Acnience Cream 50ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
Creators trying on authentic Korean skincare routines and products from us.
Rating a shelf of Dr. Althea products one by one.
Jasmine Loo · YouTube
Two hydrating serums side by side, IUNIK and Dr. Althea.
Kristin · YouTube
A walk through the Dr. Althea serum lineup and who each one suits.
auraofmahmuda · YouTube
A blunt first take on the Dr. Althea range.
Lexi Chang · YouTube
A first look at the viral 345 Relief Cream before buying.
Shelley Nayak · YouTube
A first try of the Dr. Althea serum on camera.
Hannah Ziad · YouTube
Centellian24, Korean-market original
Cica blemish cream, 50 ml, with Centella Asiatica first, Niacinamide and Tea Tree.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
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