Where does this lotion go in my routine?

As the last skincare step, morning and evening, over serum. Anything thinner than a lotion goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Sodium DNA and not three changes at once.

What else is on the list besides Sodium DNA?

Niacinamide, Allantoin and Dipotassium Glycyrrhizate. The order they are printed in on this lotion's panel is the order on the box, so you can see where Sodium DNA sits relative to them. Further down the same panel: Adenosine, Madecassoside and Asiaticoside.

DERMALINE

Hycare PDRN Solution Emulsion 200ml

Name: DERMALINE Hycare PDRN Solution Emulsion 200ml
Brand: DERMALINE
SKU: 6110929485
Price: 32.5 USD
Availability: InStock

Niacinamide sits fifth in this 200 ml DERMALINE emulsion, with Squalane tenth, olive fruit oil eleventh and Trehalose thirteenth, plus sodium DNA, Copper Tripeptide-1 and Madecassoside deeper in the list. A lotion weight moisturizer for normal to dry skin.

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$32.50

200 ml

$16.25 per 100 ml

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: Dry skinCompromised barrierDehydrated skinSensitive skin

Helps with: Shoppers looking for Sodium DNA in a lotionRoutines that want Sodium DNA and Niacinamide in one stepFilling the lotion step with a Korean-market formula

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$32.50

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Key benefits

Sodium DNA, the active this lotion is built around
Niacinamide, Allantoin, Dipotassium Glycyrrhizate and Adenosine on the same list, actives
Madecassoside and Asiaticoside further down the same list
Copper Tripeptide-1 and Tripeptide-1 further down the same list
Sodium DNA named thirtieth on the manufacturer list printed on this page

Key actives

5Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is named fifth on this lotion's list, alongside Sodium DNA.

All products with Niacinamide

30Sodium DNAactive

Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to. The name on the box points at it, and it is named thirtieth on this lotion's own ingredient list.

All products with PDRN

31Allantoinactive

Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin. It is named thirty-first on this lotion's list, alongside Sodium DNA.

All products with Allantoin

33Dipotassium Glycyrrhizateactive

Dipotassium Glycyrrhizate is a water-soluble salt derived from licorice root. The panel names it thirty-third on this lotion's list, beside Sodium DNA.

All products with Dipotassium Glycyrrhizate

35Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. The panel names it thirty-fifth on this lotion's list, beside Sodium DNA.

All products with Adenosine

Inside the formula

Ingredients declared

No fragrance

on the list

5Niacinamide30Sodium DNA35Adenosine

5Niacinamide
30Sodium DNA
35Adenosine

Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.

1 of 3

60 of 62 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Caprylic/Capric Triglyceride emollient: Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Niacinamide active: Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
Ethylhexyl Palmitate emollient: Ethylhexyl Palmitate is a palm-derived ester used as a light emollient and a solvent for pigment. It gives a smooth, non-greasy slip.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Glycereth-26 humectant: Glycereth-26 is a modified glycerin that hydrates with far less stickiness than glycerin itself. It is a common way to load water into a formula that has to stay light.
Glyceryl Stearate emulsifier: Glyceryl Stearate is glycerin joined to stearic acid, and one of the most used emulsifiers in skincare. It holds oil and water together and thickens the result, and it softens skin at the same time.
Squalane emollient: Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
Olea Europaea (Olive) Fruit Oil emollient: Olive Fruit Oil is high in oleic acid and plant sterols. It is a rich emollient that suits dry skin and is heavy enough that blemish-prone skin often does not get on with it.
Coco-Caprylate/Caprate emollient: Coco-Caprylate/Caprate is a coconut-derived ester used as a light, dry emollient in place of silicone. It spreads far and leaves a soft finish.

48 more explained

Trehalose humectant: Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
Polysorbate 60 emulsifier: Polysorbate 60 is a water-loving emulsifier used with a fatty co-emulsifier to build stable lotions and creams.
Glyceryl Stearate SE emulsifier: Glyceryl Stearate SE is the self-emulsifying grade, supplied with a little soap already built in so it can hold an emulsion with less help. It thickens and softens like the plain form.
Cetearyl Olivate emulsifier: Cetearyl Olivate is the water-loving half of the olive-derived emulsifier pair. With sorbitan olivate it builds emulsions whose lipid profile is close to skin's own.
Cetyl Alcohol fatty alcohol: Cetyl Alcohol is a waxy fatty alcohol from coconut or palm, unrelated to drying ethanol. It thickens creams, stabilises the emulsion and leaves skin feeling softer.
Sorbitan Olivate emulsifier: Sorbitan Olivate is an olive-derived emulsifier, the oil-loving half of the pair sold as Olivem. It holds oil into water and leaves a light, non-waxy feel.
Sorbitan Isostearate emulsifier: Sorbitan Isostearate is a mild emulsifier that holds water into oil, the direction a cleansing balm or an oil-based cream needs.
Carbomer thickener: Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
Arginine amino acid: Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
Tocopheryl Acetate antioxidant: Tocopheryl Acetate is a stable vitamin E ester that skin converts to tocopherol. It is used as an antioxidant and a light emollient and holds up better than plain vitamin E in a formula.
Panthenol humectant: Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
Rosa Damascena Extract plant extract: Damask rose extract with the plant part unstated. Rose carries polyphenols and aromatic compounds, so the extract contributes a light scent alongside the botanical.
Hippophae Rhamnoides Water plant extract: Hippophae Rhamnoides is sea buckthorn. Its water is used in place of plain water as a base and carries traces of the fruit's vitamins.
Yeast Extract ferment: The soluble contents of yeast cells, carrying amino acids, peptides, sugars and B vitamins. It is used as a conditioning ingredient and as a source of beta glucan.
Stearyl Alcohol fatty alcohol: Stearyl Alcohol is a solid fatty alcohol used to thicken and stabilise creams. Like the other fatty alcohols it is an emollient, not a solvent.
Ammonium Acryloyldimethyltaurate/VP Copolymer thickener: This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
Betaine humectant: Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
Sodium DNA active: Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to.
Allantoin active: Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin.
Propanediol humectant: Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
Dipotassium Glycyrrhizate active: Dipotassium Glycyrrhizate is a water-soluble salt derived from licorice root. It is the licorice fraction Korean formulas use for the look of redness, and it is far more stable in water than the whole extract.
Aloe Barbadensis Leaf Extract plant extract: Aloe Leaf Extract is mostly water with polysaccharides, amino acids and mild plant acids. It hydrates and leaves a light, cooling film, which is why it is the default after-sun ingredient.
Adenosine active: Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
Octyldodecanol emollient: Octyldodecanol is a branched fatty alcohol used as an emollient and as a solvent for pigments and mineral powders. It thickens slightly and leaves a soft finish.
Sodium Hyaluronate humectant: Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
Disodium EDTA chelator: EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
Hydrogenated Lecithin emulsifier: Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
Ceramide NP barrier lipid: Ceramide NP is the most used cosmetic ceramide, the same class of lipid that makes up roughly half the mortar between cells in the outer layer of skin. Added to a cream it slots into that structure, which is why ceramide formulas feel less leaky rather than merely greasy.
Madecassoside active: Madecassoside is the centella triterpene most associated with the look of redness, and the one brands lead with in cica products. It is water soluble and stable, so it appears in essences as readily as in creams.
Caviar Extract protein: Caviar Extract is an extract of sturgeon roe, carrying proteins, amino acids and lipids. It is a fish-derived ingredient.
Maltodextrin film former: Maltodextrin is a starch-derived sugar chain used to carry powdered extracts and to form a light film. It also gives a soft, smoothing feel.
Biosaccharide Gum-1 polysaccharide: Biosaccharide Gum-1 is a fermentation-derived sugar polymer that binds to skin and holds a moisture film in place. It gives a silky, non-tacky feel.
Polyglyceryl-10 Laurate emulsifier: Polyglyceryl-10 Laurate is a sugar-derived emulsifier and solubiliser, mild enough to be a standard choice in Korean essences. It dissolves small amounts of oil into water without any tightening feel.
Hydrolyzed Corn Starch absorbent: Hydrolyzed Corn Starch is starch broken into smaller fragments. It gives a silky, powdery slip and absorbs a little oil.
Asiaticoside active: Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised.
Sucrose humectant: Sucrose is table sugar, used here as a humectant. It draws water into the outer layer of skin and, in a scrub, doubles as the physical grain.
Triethanolamine pH adjuster: Triethanolamine is an alkaline base used to neutralise acidic gelling agents such as carbomer. Once neutralised the gel thickens, which is what holds a clear gel together.
Caprylyl Glycol preservative booster: Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
Eclipta Prostrata Leaf Extract plant extract: Eclipta Prostrata is false daisy, long used in Ayurvedic and East Asian practice. Its extract is used as a conditioning plant extract, most often in scalp and hair formulas.
Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Dextrin thickener: Dextrin is a starch fragment used to thicken and to give a formula a light, powdery finish. It is also a common carrier for powdered extracts.
Hydroxypropyl Methylcellulose thickener: Hydroxypropyl Methylcellulose is modified plant cellulose. It thickens water, forms a film, and stabilises foam, and it is the same material used to make capsule shells.
Copper Tripeptide-1 peptide: Copper Tripeptide-1 is three amino acids bound to a copper ion, and the classic firming peptide in cosmetic chemistry. It is blue in solution, which is often why a serum carrying it is tinted, and it is used for the look of firmness and fine lines.
Tripeptide-1 peptide: Tripeptide-1 is the copper-free version of the classic three-amino-acid peptide. It is used for the look of firmness in formulas that avoid copper's blue tint.
Palmitoyl Tripeptide-1 peptide: Palmitoyl Tripeptide-1 is a short peptide with a fatty tail added so it can travel through the oily outer layer of skin. It is used for the look of firmness and is almost always paired with palmitoyl tetrapeptide-7.
Palmitoyl Pentapeptide-4 peptide: Palmitoyl Pentapeptide-4 is the five-amino-acid peptide originally sold as Matrixyl. It is used for the look of fine lines and is one of the longest-standing cosmetic peptides.
Hexapeptide-11 peptide: Hexapeptide-11 is a yeast-derived six-amino-acid peptide used for the look of resilience and firmness.
Hexapeptide-9 peptide: Hexapeptide-9 is a six-amino-acid peptide used for the look of firmness and elasticity. It is water soluble and appears in peptide blends rather than alone.

How it works

The Hycare PDRN Solution Emulsion is a 200ml lotion, used as the last skincare step, morning and evening, over serum. The active it is built around is Sodium DNA, named thirtieth on its own ingredient list. The same list carries Niacinamide, Allantoin and Dipotassium Glycyrrhizate, so the active is not the only thing on it worth naming. How much of the Sodium DNA stays on the skin, and for how long, is decided by the lotion format rather than by the list alone. DERMALINE sells this Sodium DNA lotion in Korea, and this is that version.

How to use

Apply after essence or serum and before a heavier cream, morning and/or night, as a lighter-weight moisturizing step.

Worth knowing

Patch test this lotion on a small area and wait a day before using it more widely, especially with Sodium DNA on the list.
Introduce this lotion on its own for the first week, so anything your skin does is traceable to the Sodium DNA rather than to three changes at once.

Complete the routine

This itemDERMALINE Hycare PDRN Solution Emulsion 200ml$32.50
From the same Korean-market lineDERMALINE Perfect 3 Shield Blemish Balm SPF50+ PA+++ 50ml$62.50
Seal the routine in as the last stepDERMALINE Bio Activing PDRN Cream 100g$132.50

Total for 3 items$227.50

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DERMALINE Hycare PDRN Solution Emulsion 200ml

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DERMALINE, Korean-market original

The Original Korean Formula lotion from DERMALINE, 200ml formulated with Sodium DNA and Niacinamide, shipped from California or direct from Korea.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

Allantoin can tone down the dryness of the individual cells. It increases the water content of the skin, which means it helps to hydrate and moisturize.
Wilma Bergfeld, MDDermatologist, Cleveland Clinic
It's still a very new ingredient in the field of regenerative medicine.
Catherine ChangBeverly Hills board-certified plastic and reconstructive surgeon, Harper's Bazaar

1 more professional perspective

Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.
Ashlyn YankeAesthetician, Cleveland Clinic