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KOREAN PHARMACY

IOPE XMD STEM III Clinical Recovery Cream 50ml

IOPE MD STEM III Clinical Recovery Cream is a 50ml cream with Niacinamide, used as the last skincare step, morning and evening, over serum.

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$117.50
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Suited to
Dry skinCompromised barrierDehydrated skinSensitive skin
Helps with
Shoppers looking for Niacinamide in a creamRoutines that want Niacinamide and Allantoin in one stepFilling the cream step with a Korean-market formula

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How it works

The MD STEM III Clinical Recovery Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Niacinamide, named eighth on its own ingredient list. The same list carries Allantoin, Adenosine and Hydrolyzed DNA, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the cream format rather than by the list alone. IOPE sells this Niacinamide cream in Korea, and this is that version.

Key benefits

  • Niacinamide, the active this cream is built around
  • Allantoin, Adenosine, Hydrolyzed DNA and Asiaticoside on the same list, actives
  • Madecassic Acid and Asiatic Acid further down the same list
  • Acetyl Tetrapeptide-11 and Tocopherol further down the same list
  • Niacinamide named eighth on the manufacturer list printed on this page

Key actives

Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. On this cream's own ingredient list it is named eighth.

Allantoinactive

Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin. It is named fifteenth on this cream's list, alongside Niacinamide.

Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. It is named twenty-fourth on this cream's list, alongside Niacinamide.

Hydrolyzed DNAactive

Hydrolyzed DNA is DNA cut into short fragments so it dissolves and spreads. It is the same ingredient family as sodium DNA and polydeoxyribonucleotide, the one Korean formulas market as PDRN. The panel names it twenty-sixth on this cream's list, beside Niacinamide.

Asiaticosideactive

Asiaticoside is one of the four active triterpenes isolated from centella and the most studied of them. Korean formulas name it separately when they want to show which fraction of the plant they standardised. The panel names it thirtieth on this cream's list, beside Niacinamide.

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IOPE XMD STEM III Clinical Recovery Cream 50ml

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How to use

  1. Smooth over the face as one of the last steps of a routine, morning or night.

Worth knowing

  • Patch test this cream on a small area and wait a day before using it more widely, especially with Niacinamide on the list.
  • Introduce this cream on its own for the first week, so anything your skin does is traceable to the Niacinamide rather than to three changes at once.

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Korean-market original

The Original Korean Formula cream from IOPE, 50ml formulated with Niacinamide and Allantoin, held in the United States and shipped domestically.

Verify your unit when it arrives

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Match the batch code on the box against the code printed on the bottle or tube itself; the two are stamped separately and should agree.

On the unit itself

  • The Korean-market barcode, unaltered from the retail package.
  • The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

  • Allantoin can tone down the dryness of the individual cells. It increases the water content of the skin, which means it helps to hydrate and moisturize.

    Wilma Bergfeld, MDDermatologist, Cleveland Clinic
  • Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.

    Ashlyn YankeAesthetician, Cleveland Clinic
1 more professional perspective
  • It's still a very new ingredient in the field of regenerative medicine.

    Catherine ChangBeverly Hills board-certified plastic and reconstructive surgeon, Harper's Bazaar

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