Is Betaine also in this formula?

Betaine sits in the middle of the ingredient list, a humectant and comfort ingredient common across Korean bases. It sits alongside Panthenol on MEDIHEAL's ingredient list for this product.

How is this skincare formula used in a routine?

Apply to cleansed skin as directed and follow with the next step of a routine. It works as a routine step suited to the format of the product.

Who is this skincare formula suited for?

Sensitive skin, Normal skin are the best fit for this skincare formula. Patch test on the inner arm before first full use, as with any new skincare product.

MEDIHEAL

Derma 365 Madecassoside Mask (30 Masks)

Name: MEDIHEAL Derma 365 Madecassoside Mask (30 Masks)
Brand: MEDIHEAL
SKU: 10186936444
Price: 30.0 USD
Availability: InStock

Derma 365 Madecassoside Mask (30 Masks) is MEDIHEAL's skincare formula, a Korean-market formula built around Panthenol named on its own manufacturer ingredient list.

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$30.00

30 sheets

Korean-market formula
Ships from California or direct from Korea
Korean barcode and batch code intact

Suited to: Sensitive skinNormal skinDry skin

Helps with: A formula built around PanthenolA routine stepA layered Korean routine

One-time purchase

$30.00

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$27.00

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Key benefits

MEDIHEAL's Derma 365 Madecassoside Mask (30 Masks), sourced for the Korean market rather than reformulated for US shelves
Formulated around Panthenol, named on the manufacturer's own ingredient list
Formulated around Betaine, named on the manufacturer's own ingredient list
Formulated around Trehalose, named on the manufacturer's own ingredient list
Functions as a routine step suited to the format of the product

Key actives

8Panthenol

Panthenol (pro-vitamin B5) sits within the first ten ingredients as the formula's moisture-retention and comfort ingredient, a standard soothing base in Korean-market formulas.

All products with Panthenol

10Betaine

Betaine sits in the middle of the ingredient list, a humectant and comfort ingredient common across Korean bases.

All products with Betaine

12Trehalose

Trehalose sits in the middle of the ingredient list, a sugar-derived humectant that helps the formula hold moisture at the skin surface.

All products with Trehalose

24Sodium Hyaluronate

Sodium Hyaluronate sits further down the ingredient list, one of this formula's moisture-binding hyaluronate forms.

All products with Sodium Hyaluronate

Inside the formula

Ingredients declared

#19

Fragrance on the list

8Panthenol12Trehalose24Sodium Hyaluronate

8Panthenol
12Trehalose
24Sodium Hyaluronate

Where each key active sits on the declared ingredient list, by entry number. Position is proportion: the further forward, the larger its share.

1 of 3

50 of 52 explained

Water solvent: Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
Glycerin humectant: Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
Dipropylene Glycol humectant: Dipropylene Glycol is a glycol used as a solvent and a light humectant. Its main job is keeping the rest of the formula dissolved and the texture fluid rather than adding hydration of its own.
Glycereth-26 humectant: Glycereth-26 is a modified glycerin that hydrates with far less stickiness than glycerin itself. It is a common way to load water into a formula that has to stay light.
1,2-Hexanediol humectant: 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
Caprylyl Glycol preservative booster: Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
Polyglyceryl-10 Laurate emulsifier: Polyglyceryl-10 Laurate is a sugar-derived emulsifier and solubiliser, mild enough to be a standard choice in Korean essences. It dissolves small amounts of oil into water without any tightening feel.
Panthenol humectant: Panthenol is pro-vitamin B5: skin converts it to pantothenic acid. It is a humectant that holds water and leaves skin feeling soft and less tight, and it is one of the ingredients formulators reach for when a formula also contains something harsh.
Betaine humectant: Betaine is a sugar-beet-derived humectant that cells use to hold water. In a formula it hydrates and takes the edge off cleansers and acids, which is why it often appears alongside them.
Hydroxyacetophenone preservative booster: Hydroxyacetophenone is an antioxidant that also strengthens a preservative system, so a formula needs less traditional preservative. Korean formulas pair it with 1,2-hexanediol constantly.
Trehalose humectant: Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
Polyglyceryl-4 Laurate emulsifier: A short polyglycerin ester used as a mild emulsifier and cleansing agent. It is common in balms designed to melt on skin and then rinse away.

38 more explained

Ethylhexylglycerin preservative booster: Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
Arginine amino acid: Arginine is an amino acid that does two jobs here: it holds water in the outer layer of skin, and it neutralises acidic gelling agents, which is why it often stands in for a synthetic pH adjuster.
Carbomer thickener: Carbomer is a synthetic polymer that only gels once a base neutralises it, which is why arginine or tromethamine sits nearby on the list. It gives the clear, non-stringy gel texture a xanthan formula cannot reach.
Pantolactone humectant: Pantolactone is a panthenol relative used as a conditioning humectant. It softens the outer layer of skin and helps a formula feel comfortable.
Xanthan Gum thickener: Xanthan Gum is a polysaccharide made by fermenting sugar. It thickens a watery formula into a gel and holds the whole thing in suspension so nothing separates. Too much of it and a serum turns stringy, which is why it appears in fractions of a percent.
Fragrance fragrance: Fragrance, or Parfum, is a single declaration standing for a whole scent blend, which can be dozens of materials. Regulators allow it as a trade secret, so a list showing only this word does not say what the scent is made of. It is the most common trigger named by people with reactive skin.
Butylene Glycol humectant: Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
Disodium EDTA chelator: EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
Sodium Acrylates Crosspolymer-2 thickener: A cross linked acrylate polymer supplied pre-neutralised, so it thickens water without a separate pH step. It gives a light gel with a fresh, non-tacky break.
Mentha Arvensis Leaf Oil fragrance: Cornmint oil, the main commercial source of menthol. It smells and feels close to peppermint.
Sodium Hyaluronate humectant: Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
Hydrolyzed Extensin protein: Extensin is a structural glycoprotein from plant cell walls. Hydrolysed, it is cut into fragments small enough to dissolve, and it works as a water-holding film on the surface.
Glyceryl Glucoside humectant: Glyceryl Glucoside is glycerin bound to glucose, from the resurrection plant. It is a humectant that holds water in the outer layer of skin.
Barosma Betulina Leaf Extract plant extract: Buchu leaf extract, a South African botanical. The leaf carries flavonoids and aromatic oils, and the extract is used as a conditioning botanical with a faint blackcurrant scent.
Saccharomyces Ferment Filtrate ferment: Saccharomyces Ferment Filtrate is a brewers yeast ferment filtered clear. It supplies amino acids, B vitamins and sugars, and it is one of the ferments the Korean essence category was built on.
Rosa Damascena Flower Water plant extract: Rosa Damascena Flower Water is the water left from distilling rose petals. It is used in place of plain water as a base and carries the scent and trace compounds of the distillation.
Daucus Carota Sativa (Carrot) Root Extract plant extract: Carrot Root Extract carries carotenoids, which give it a strong orange colour. It is used as an antioxidant extract and can tint a formula.
Glycine amino acid: Glycine is the smallest amino acid and one of the free amino acids skin holds to keep water in the outer layer. In a formula it is a humectant and a mild buffer.
Glutamic Acid amino acid: Glutamic Acid is an amino acid used as a humectant and a mild pH adjuster. It is one of the components of skin's natural moisturising factor.
Tremella Fuciformis Polysaccharide plant extract: Tremella Fuciformis is snow mushroom. Its polysaccharide holds even more water than hyaluronic acid for its weight, which is why it appears in hydrating Korean formulas as a plant alternative.
Aspartic Acid amino acid: Aspartic Acid is an amino acid used as a humectant and buffer, usually within a wider amino acid blend.
Linum Usitatissimum (Linseed) Seed Extract plant extract: Flaxseed extract. Flaxseed swells into a mucilage in water, so the extract hydrates and leaves a cushioned, slippery feel.
Pantothenic Acid vitamin: Pantothenic Acid is vitamin B5, the form skin converts panthenol into. It is used as a conditioning humectant that leaves skin feeling soft rather than tight.
Sodium Polyacrylate thickener: Sodium Polyacrylate is a polymer that absorbs many times its weight in water. It thickens a formula and holds water in a gel against the skin.
Silica absorbent: Silica is finely milled mineral, essentially very pure sand. It absorbs oil, stops powders clumping and soft-focuses the look of pores and fine lines.
Sodium Chloride thickener: Sodium Chloride is salt. In a cleanser it thickens the liquid; in a mask or essence it balances the mineral content of the water phase. It has no active role.
Histidine amino acid: Histidine is an amino acid used as a humectant and a buffer, part of skin's own free amino acid pool.
Serine amino acid: Serine is one of the most abundant free amino acids in the outer layer of skin, where it helps hold water. Added to a formula it is a humectant.
Alanine amino acid: Alanine is a free amino acid skin uses as part of its own moisture-holding system. In a formula it hydrates and conditions.
Proline amino acid: Proline is an amino acid abundant in collagen and one of skin's own humectants. Added to a formula it holds water in the outer layer.
Threonine amino acid: Threonine is an essential amino acid used in skincare as a humectant, normally as part of an amino acid complex rather than alone.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener: This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
Magnesium Chloride mineral: Magnesium Chloride is the magnesium salt that makes sea water taste bitter. In a formula it is a mineral salt in the water phase and helps set gum gels.
Calcium Chloride mineral: Calcium Chloride is a mineral salt used in traces to balance a formula and to firm up gels made with alginate or gellan gum.
Glutathione antioxidant: Glutathione is a small peptide the body uses as one of its main antioxidants. In skincare it is used as an antioxidant and for the look of dullness; it is unstable in water, so formulas that carry it are usually built around protecting it.
Oligopeptide-29 peptide: A short chain of amino acids used as a conditioning peptide. Oligopeptide numbers are registry entries, not strengths.
Oligopeptide-32 peptide: A short amino acid chain used as a conditioning peptide, usually one of several oligopeptides declared together.
Palmitoyl Pentapeptide-4 peptide: Palmitoyl Pentapeptide-4 is the five-amino-acid peptide originally sold as Matrixyl. It is used for the look of fine lines and is one of the longest-standing cosmetic peptides.

How it works

Mediheal is a Korean sheet mask specialist whose clinic-inspired, single-use format has become one of the most recognised on Olive Young's shelves, and Derma 365 Madecassoside Mask (30 Masks) is one of its skincare formula entries. Panthenol (pro-vitamin B5) sits within the first ten ingredients as the formula's moisture-retention and comfort ingredient, a standard soothing base in Korean-market formulas. Betaine sits in the middle of the ingredient list, a humectant and comfort ingredient common across Korean bases. Trehalose sits in the middle of the ingredient list, a sugar-derived humectant that helps the formula hold moisture at the skin surface. Sodium Hyaluronate sits further down the ingredient list, one of this formula's moisture-binding hyaluronate forms. As a skincare formula, it functions as a routine step suited to the format of the product in a layered Korean routine. It comes in a 30sheets format.

How to use

Apply to cleansed skin as directed and follow with the next step of a routine.

Worth knowing

Patch test on the inner arm before first full use, as with any new skincare product.

Complete the routine

This itemMEDIHEAL Derma 365 Madecassoside Mask (30 Masks)$30.00
The treatment step of this routineMEDIHEAL Tea Tree Calming Barrier Ampoule 50ml$37.50
Cleanse first, so the next step meets bare skinMEDIHEAL Teatree Trouble Calming Cleanser 120ml$15.00

Total for 3 items$82.50

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MEDIHEAL Derma 365 Madecassoside Mask (30 Masks)

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MEDIHEAL, Korean-market original

MEDIHEAL's Derma 365 Madecassoside Mask (30 Masks), sourced for the Korean market.

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

On the unit itself

The Korean-market barcode, unaltered from the retail package.
The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

Pantothenol is a common ingredient in skin care and hair products I recommend, particularly for people who are prone to dryness.
Taylor Bullock, MDDermatology resident, Cleveland Clinic
Hyaluronic acid helps bind water to collagen, which traps water in the skin. That helps make the skin more plump and full-looking.
Samantha Stein, PA-CDermatology physician assistant, Cleveland Clinic