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KOREAN PHARMACY

Isntree GIM PDRN Hydro Firming Cream 50ml

Squalane sits second and Niacinamide fifth in this 50 ml Isntree cream, with sodium DNA (PDRN), Ectoin, Trehalose, Copper Tripeptide-1 and Acetyl Hexapeptide-8 behind them. A firming moisturizer for dehydrated skin at the last step. Korean-market formula.

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$45.00
  • Ships from our California warehouse
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Suited to
Congested skinUneven textureDehydrated skinSensitive skin
Helps with
Shoppers looking for Sodium DNA in a creamRoutines that want Sodium DNA and Niacinamide in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Sodium DNA cream sold on Korean shelves

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How it works

The GIM PDRN Hydro Firming Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Sodium DNA, named eighteenth on its own ingredient list. The same list carries Niacinamide, Adenosine and Gluconolactone, so the active is not the only thing on it worth naming. How much of the Sodium DNA stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream Isntree sells in Korea, Sodium DNA and all.

Key benefits

  • Sodium DNA, the active this cream is built around
  • Niacinamide and Adenosine on the same list, actives
  • Gluconolactone on the same list, an exfoliant
  • Acetyl Hexapeptide-8 on the same list, a peptide
  • Copper Tripeptide-1 and Palmitoyl Tetrapeptide-7 further down the same list
  • Nonapeptide-1 and Tripeptide-1 further down the same list

Key actives

Sodium DNAactive

Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to. The name on the box points at it, and it is named eighteenth on this cream's own ingredient list.

Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is named fifth on this cream's list, alongside Sodium DNA.

Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. It is named sixteenth on this cream's list, alongside Sodium DNA.

Gluconolactoneexfoliant

Gluconolactone is a PHA, the gentlest exfoliant class. The panel names it thirty-first on this cream's list, beside Sodium DNA.

Acetyl Hexapeptide-8peptide

Acetyl Hexapeptide-8 is a six-amino-acid peptide used for the look of expression lines, particularly around the eyes. It is the peptide sold under the name Argireline and is water soluble and stable. The panel names it thirty-ninth on this cream's list, beside Sodium DNA.

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Isntree GIM PDRN Hydro Firming Cream 50ml

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How to use

  1. Use it as the final leave on step, after any ampoule or serum has settled.
  2. Warm a small amount between your fingers, then press it upward across the cheeks and jaw.
  3. Carry the same amount down onto the neck, which is usually the area people skip.
  4. Do not apply it right up to the lash line, because a cushioned cream migrates into the eye overnight.

Worth knowing

  • Patch test this cream on a small area and wait a day before using it more widely, especially with Sodium DNA on the list.
  • Gluconolactone on this list makes this cream an exfoliating step, so do not stack it with another one on the same night.

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We’re on gram!

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Korean-market original

The Original Korean Formula cream from Isntree, 50ml formulated with Sodium DNA and Niacinamide, held in the United States and shipped domestically.

Verify your unit when it arrives

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Match the batch code on the box against the code printed on the bottle or tube itself; the two are stamped separately and should agree.

On the unit itself

  • The Korean-market barcode, unaltered from the retail package.
  • The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

  • It's still a very new ingredient in the field of regenerative medicine.

    Catherine ChangBeverly Hills board-certified plastic and reconstructive surgeon, Harper's Bazaar
  • Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.

    Ashlyn YankeAesthetician, Cleveland Clinic
1 more professional perspective
  • This means that gluconolactone acts as an exfoliating acid, but also as a moisturizer. It has moisturizing, soothing, and lightening properties, working well on dry skin.

    Paola PeruginiPhD, Journal of Cosmetic Dermatology

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