Medicube
PDRN Pink Collagen Capsule Cream$19.99Isntree
GIM PDRN Hydro Firming Cream 50ml
Squalane sits second and Niacinamide fifth in this 50 ml Isntree cream, with sodium DNA (PDRN), Ectoin, Trehalose, Copper Tripeptide-1 and Acetyl Hexapeptide-8 behind them. A firming moisturizer for dehydrated skin at the last step. Korean-market formula.
No reviews yet50 ml
$90.00 per 100 ml
- Korean-market formula
- Ships from California or direct from Korea
- Korean barcode and batch code intact
- Suited to
- Congested skinUneven textureDehydrated skinSensitive skin
- Helps with
- Shoppers looking for Sodium DNA in a creamRoutines that want Sodium DNA and Niacinamide in one stepFilling the cream step with a Korean-market formulaAnyone who wants the Sodium DNA cream sold on Korean shelves
In stock. Arrives in 3 to 7 business days
We accept
You’re $100.00 away from free US shipping.
- 30-day returns
- Free US shipping on orders of $100 or more
- Tracked delivery to your door
How it works
The GIM PDRN Hydro Firming Cream is a 50ml cream, used as the last skincare step, morning and evening, over serum. The active it is built around is Sodium DNA, named eighteenth on its own ingredient list. The same list carries Niacinamide, Adenosine and Gluconolactone, so the active is not the only thing on it worth naming. How much of the Sodium DNA stays on the skin, and for how long, is decided by the cream format rather than by the list alone. This is the Original Korean Formula, the cream Isntree sells in Korea, Sodium DNA and all.
Key benefits
- Sodium DNA, the active this cream is built around
- Niacinamide and Adenosine on the same list, actives
- Gluconolactone on the same list, an exfoliant
- Acetyl Hexapeptide-8 on the same list, a peptide
- Copper Tripeptide-1 and Palmitoyl Tetrapeptide-7 further down the same list
- Nonapeptide-1 and Tripeptide-1 further down the same list
Inside the formula
Inside the formula
Where does this cream go in my routine?
As the last skincare step, morning and evening, over serum. Anything thinner than a cream goes on before it, and anything richer goes on after. If you are adding it to a routine you already like, give it a week on its own first, so what you see is the Sodium DNA and not three changes at once.
Is this the Korean-market cream or a US version?
The Korean-market one, Sodium DNA and all. We match this cream to its Korean barcode before it reaches the shelf, which is the check that tells you which market release you are holding.
What else is on the list besides Sodium DNA?
Niacinamide, Adenosine and Gluconolactone. The order they are printed in on this cream's panel is the order on the box, so you can see where Sodium DNA sits relative to them. Further down the same panel: Acetyl Hexapeptide-8, Copper Tripeptide-1 and Palmitoyl Tetrapeptide-7.
Not on the ingredient list below: fragrance or parfum, denatured or SD alcohol, essential oils, silicones, parabens, sulfate surfactants, mineral oil or petrolatum and added color.
Full INCI (47): WATER, SQUALANE, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, METHYL GLUCETH-20, 1,2-HEXANEDIOL, SODIUM POLYACRYLOYLDIMETHYL TAURATE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, HYDROXYACETOPHENONE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, COPTIS JAPONICA ROOT EXTRACT, TROMETHAMINE, PORPHYRA YEZOENSIS EXTRACT, ETHYLHEXYLGLYCERIN, ADENOSINE, DISODIUM EDTA, SODIUM DNA, MALTODEXTRIN, HYDROLYZED GARDENIA FLORIDA EXTRACT, TREHALOSE, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL, LAMINARIA JAPONICA EXTRACT, ENTEROMORPHA COMPRESSA EXTRACT, UNDARIA PINNATIFIDA EXTRACT, SARGASSUM FULVELLUM EXTRACT, SARGASSUM FUSIFORME EXTRACT, HYDROGENATED LECITHIN, ECTOIN, GLUCONOLACTONE, PROPANEDIOL, SODIUM HYALURONATE CROSSPOLYMER, HYDROLYZED GLYCOSAMINOGLYCANS, SODIUM HYALURONATE, BENZYL GLYCOL, CAPRYLYL GLYCOL, HYDROLYZED HYALURONIC ACID, ACETYL HEXAPEPTIDE-8, COPPER TRIPEPTIDE-1, PALMITOYL TETRAPEPTIDE-7, HYALURONIC ACID, NONAPEPTIDE-1, TRIPEPTIDE-1, PALMITOYL PENTAPEPTIDE-4, PALMITOYL TRIPEPTIDE-1, HEXAPEPTIDE-9
Ingredient list read from isntree-global.com on 10 September 2026.
46 of 47 explained
- WATER solvent
- Water is the base almost every serum, toner and cream is built on. It dissolves the water-loving ingredients and sets how light the finished texture feels. On an INCI list it is usually first, which only means it is the largest single ingredient by weight.
- SQUALANE emollient
- Squalane is the stable, saturated version of squalene, a lipid human skin already makes. It is a light emollient that absorbs quickly, does not oxidise, and is one of the few oils widely considered safe for blemish-prone skin. Most cosmetic squalane is now from sugarcane or olive rather than shark.
- BUTYLENE GLYCOL humectant
- Butylene Glycol is a small glycol that does two jobs at once: it holds water in the top layer of skin and it dissolves plant extracts and actives that plain water cannot. It also thins a formula, which is why watery Korean essences lean on it.
- GLYCERIN humectant
- Glycerin is the most used humectant in skincare. It draws water into the outer layer of skin and holds it there, and it is one of the very few ingredients whose hydrating effect is settled science rather than marketing. Higher amounts feel tacky, which is why it is usually blended.
- NIACINAMIDE active
- Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. It is used at roughly 2 to 5 percent for the look of uneven tone and visible pores, and it is water soluble, stable and comfortable beside almost every other active, which is why it turns up in so many lists.
- METHYL GLUCETH-20 humectant
- Methyl Gluceth-20 is a sugar-derived humectant. It holds water in the outer layer of skin and gives a smooth, cushioned slip that plain glycerin does not.
- 1,2-HEXANEDIOL humectant
- 1,2-Hexanediol is a glycol used for two reasons: it holds water like glycerin, and it makes a formula harder for microbes to live in, so less traditional preservative is needed. Korean formulas use it heavily for that second reason.
- SODIUM POLYACRYLOYLDIMETHYL TAURATE thickener
- Sodium Polyacryloyldimethyl Taurate is a polymer thickener that holds a gel stable even with a lot of salt or acid in the formula.
- AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER thickener
- This is a synthetic thickener that gels quickly and holds an emulsion stable across a wide pH range. It gives a light, non-tacky body.
- HYDROXYACETOPHENONE preservative booster
- Hydroxyacetophenone is an antioxidant that also strengthens a preservative system, so a formula needs less traditional preservative. Korean formulas pair it with 1,2-hexanediol constantly.
- ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER thickener
- This is a carbomer relative with fatty side chains, so it thickens and stabilises an emulsion at the same time. It gives a light gel-cream body rather than a heavy one.
- COPTIS JAPONICA ROOT EXTRACT plant extract
- Coptis Japonica is a traditional East Asian medicinal root, bright yellow from its berberine content. In skincare its extract is used for the look of congested, oily skin.
34 more explained
- TROMETHAMINE pH adjuster
- Tromethamine neutralises acidic thickeners such as carbomer so they gel, and holds a formula near skin-friendly pH. It is used at a fraction of a percent.
- PORPHYRA YEZOENSIS EXTRACT plant extract
- Nori laver, the gim eaten in Korea and Japan. Its extract carries porphyran, a water-holding sugar, along with minerals and amino acids.
- ETHYLHEXYLGLYCERIN preservative booster
- Ethylhexylglycerin softens skin and boosts a preservative system, which is why it is nearly always sitting beside phenoxyethanol or 1,2-hexanediol. It also cuts down the odour bacteria produce, so it turns up in deodorising products.
- ADENOSINE active
- Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated.
- DISODIUM EDTA chelator
- EDTA is a chelator: it locks up trace metal ions from water and packaging that would otherwise turn a formula cloudy, off-colour or rancid. It does nothing to skin and appears at a fraction of a percent.
- SODIUM DNA active
- Sodium DNA is the salt of DNA, in Korean skincare almost always salmon derived, and it is the ingredient behind the PDRN category. It is used as a humectant and for the look of tired skin; the fragments themselves are what the name PDRN refers to.
- MALTODEXTRIN film former
- Maltodextrin is a starch-derived sugar chain used to carry powdered extracts and to form a light film. It also gives a soft, smoothing feel.
- HYDROLYZED GARDENIA FLORIDA EXTRACT plant extract
- Hydrolyzed Gardenia Florida Extract is gardenia extract broken into smaller fragments so a water-based formula can carry it evenly.
- TREHALOSE humectant
- Trehalose is a sugar that some desert plants use to survive drying out. In skincare it is a humectant that holds water in the outer layer and helps a formula feel comfortable rather than tight.
- CAPRYLIC/CAPRIC TRIGLYCERIDE emollient
- Caprylic/Capric Triglyceride is the light fraction of coconut oil, with the heavy parts removed. It is the workhorse emollient of modern formulas: it softens skin, dissolves oil-soluble actives and absorbs without the greasy weight of a whole plant oil.
- TOCOPHEROL antioxidant
- Tocopherol is vitamin E. It is an oil-soluble antioxidant that protects the oils in a formula from going rancid and works on skin as an emollient, and it is regularly paired with vitamin C because each keeps the other going for longer.
- LAMINARIA JAPONICA EXTRACT plant extract
- Laminaria Japonica is kombu kelp. Its extract carries alginates, minerals and iodine, and it is used as a hydrating, mineral-rich ingredient.
- ENTEROMORPHA COMPRESSA EXTRACT plant extract
- Green laver, the parae of Korean cooking. Its extract is a mineral-rich, hydrating seaweed ingredient.
- UNDARIA PINNATIFIDA EXTRACT plant extract
- Extract of the brown seaweed Korean cooking calls miyeok. It carries fucoidan and alginates, both strong water-holding polysaccharides.
- SARGASSUM FULVELLUM EXTRACT plant extract
- Mojaban, a Korean brown seaweed. Its extract carries alginates, minerals and polyphenols and is used as a hydrating marine ingredient.
- HYDROGENATED LECITHIN emulsifier
- Hydrogenated Lecithin is lecithin with its unsaturated bonds filled in, which makes it far more stable. It emulsifies and is the standard shell for the liposomes that carry actives into the outer layer of skin.
- ECTOIN humectant
- Ectoin is a small molecule that microbes in salt flats and hot springs make to survive extreme conditions. In skincare it holds water tightly around itself, which is why it appears in formulas aimed at reactive, easily dehydrated skin.
- GLUCONOLACTONE exfoliant
- Gluconolactone is a PHA, the gentlest exfoliant class. Its molecule is too large to penetrate quickly, so it smooths the surface without the sting of an AHA, and it is a humectant at the same time.
- PROPANEDIOL humectant
- Propanediol is a plant-derived glycol used in place of propylene glycol. It hydrates, carries actives into solution, and gives a lighter, less sticky slip than glycerin at the same strength.
- SODIUM HYALURONATE CROSSPOLYMER humectant
- Sodium Hyaluronate Crosspolymer is hyaluronic acid linked into a mesh. It holds water in a soft gel on the surface rather than sinking in, and it releases that water slowly through the day.
- HYDROLYZED GLYCOSAMINOGLYCANS humectant
- Hydrolyzed Glycosaminoglycans are short fragments of the sugar chains that sit between cells in skin, hyaluronic acid among them. They act as humectants and give a cushioned feel.
- SODIUM HYALURONATE humectant
- Sodium Hyaluronate is the salt of hyaluronic acid, and it is what most products labelled hyaluronic actually contain. The salt dissolves more readily and the molecule is smaller, so it sits in the outer layer of skin rather than only on top of it.
- BENZYL GLYCOL preservative booster
- Benzyl Glycol is a solvent that also makes a formula less hospitable to microbes, so it appears in preservative blends built without parabens.
- CAPRYLYL GLYCOL preservative booster
- Caprylyl Glycol is a glycol that conditions skin and, more importantly, strengthens a preservative system so less of the traditional preservative is needed. It appears in most modern formulas built without parabens.
- HYDROLYZED HYALURONIC ACID humectant
- Hydrolyzed Hyaluronic Acid is hyaluronic acid cut into much shorter fragments. The smaller the fragment, the further into the outer layer it can settle, which is why serums stack several sizes together instead of using one.
- ACETYL HEXAPEPTIDE-8 peptide
- Acetyl Hexapeptide-8 is a six-amino-acid peptide used for the look of expression lines, particularly around the eyes. It is the peptide sold under the name Argireline and is water soluble and stable.
- COPPER TRIPEPTIDE-1 peptide
- Copper Tripeptide-1 is three amino acids bound to a copper ion, and the classic firming peptide in cosmetic chemistry. It is blue in solution, which is often why a serum carrying it is tinted, and it is used for the look of firmness and fine lines.
- PALMITOYL TETRAPEPTIDE-7 peptide
- Palmitoyl Tetrapeptide-7 is a four-amino-acid peptide with a fatty tail, used for the look of fine lines. With palmitoyl tripeptide-1 it forms the pairing sold as Matrixyl 3000.
- HYALURONIC ACID humectant
- Hyaluronic Acid is a sugar chain the body already makes, and one gram of it can hold several litres of water. In a formula it is a humectant that pulls water to the surface of skin and holds it in a film, which is what makes skin look plumper while it is there.
- NONAPEPTIDE-1 peptide
- Nonapeptide-1 is a nine-amino-acid peptide used for the look of uneven tone rather than for firmness, which makes it unusual among cosmetic peptides.
- TRIPEPTIDE-1 peptide
- Tripeptide-1 is the copper-free version of the classic three-amino-acid peptide. It is used for the look of firmness in formulas that avoid copper's blue tint.
- PALMITOYL PENTAPEPTIDE-4 peptide
- Palmitoyl Pentapeptide-4 is the five-amino-acid peptide originally sold as Matrixyl. It is used for the look of fine lines and is one of the longest-standing cosmetic peptides.
- PALMITOYL TRIPEPTIDE-1 peptide
- Palmitoyl Tripeptide-1 is a short peptide with a fatty tail added so it can travel through the oily outer layer of skin. It is used for the look of firmness and is almost always paired with palmitoyl tetrapeptide-7.
- HEXAPEPTIDE-9 peptide
- Hexapeptide-9 is a six-amino-acid peptide used for the look of firmness and elasticity. It is water soluble and appears in peptide blends rather than alone.
- Market
- Korean market, the version sold in Korea
- EAN (barcode)
- 8809800942457
- Made in
- Republic of Korea
- Volume
- 50 ml
- Category
- Moisturizer
- Actives
- Adenosine, Ectoin, Hyaluronic Acid, Niacinamide, PDRN (Sodium DNA), Peptides, Sodium Hyaluronate, Squalane, Trehalose
- Ships from
- California or Korea
Orders ship from California or direct from Korea with tracked delivery to your door, and both routes carry the same Korean-market release. Shipping is free on orders of $100 or more. Returns are accepted for 30 days, by mail.
We split shipments free, so one out-of-stock item never holds up the rest of your order.
Where this unit came from
- 1Seoul
Bought as Korean-market stock - 2Barcode
Listed against the Korean barcode on its box - 3California or Korea
Ships to you from either, as the same Korean-market release
We stock the version of a formula that is sold in Korea, not the release a brand prepares for another market under the same name. The barcode in the specification above is the Korean-market one and it is printed on the box you receive.
Every unit keeps its original barcode and batch code intact, so the unit in your hands can be checked against the brand’s own records.
Every order ships from California or direct from Korea, and returns run for 30 days.
Every claim on this page traces to the unit in the box, the barcode, the batch code and the price you can read for yourself.
How to use
- Use it as the final leave on step, after any ampoule or serum has settled.
- Warm a small amount between your fingers, then press it upward across the cheeks and jaw.
- Carry the same amount down onto the neck, which is usually the area people skip.
- Do not apply it right up to the lash line, because a cushioned cream migrates into the eye overnight.
Worth knowing
- Patch test this cream on a small area and wait a day before using it more widely, especially with Sodium DNA on the list.
- Gluconolactone on this list makes this cream an exfoliating step, so do not stack it with another one on the same night.
Complete the routine
- This itemIsntree GIM PDRN Hydro Firming Cream 50ml$45.00

- The treatment step of this routineIsntree TW-REAL BIFIDA Ampoule 50ml$37.50

- Seal the routine in as the last stepIsntree C-Niacin Toning Cream 50ml$22.50

Total for 3 items$105.00
Reviews
No reviews yet. Tell us how much you love the product!
Write a reviewWrite a review
Isntree GIM PDRN Hydro Firming Cream 50ml
How it felt, how your skin took it, what you layer it with. Straight answers help the next person choose.
We’re on gram!
Creators trying on authentic Korean skincare routines and products from us.
Rating a shelf of Dr. Althea products one by one.
Jasmine Loo · YouTube
Two hydrating serums side by side, IUNIK and Dr. Althea.
Kristin · YouTube
A walk through the Dr. Althea serum lineup and who each one suits.
auraofmahmuda · YouTube
A blunt first take on the Dr. Althea range.
Lexi Chang · YouTube
A first look at the viral 345 Relief Cream before buying.
Shelley Nayak · YouTube
A first try of the Dr. Althea serum on camera.
Hannah Ziad · YouTube
Isntree, Korean-market original
The Original Korean Formula cream from Isntree, 50ml formulated with Sodium DNA and Niacinamide, shipped from California or direct from Korea.
Verify your unit when it arrives
Verify your unit when it arrives
Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.
On the unit itself
- The Korean-market barcode, unaltered from the retail package.
- The manufacturer’s batch code, exactly as the maker printed it.
정품Genuine article, Korean-market stock
What professionals say
What professionals say
What skin-care professionals say about skin care, quoted from the medical sources linked beside each.
Your skin barrier is basically your outer layer of the skin.
Melissa Piliang, MDDermatologist, Cleveland Clinic Pretty much every step of a Korean skin care routine is going to have some component of hydration.
Alok Vij, MDDermatologist, Cleveland Clinic
You may also like
Picked from the same shelf across the Korean-market lines we carry.
VT Cosmetics
VT PDRN Capsule Cream 100$14.99Dr. Melaxin
Dr.Melaxin CACTOX Pore Relief Dual Capsule Cream$22.34Sungboon Editor
Deep Collagen Retinal Power Boosting Capsule Cream$17.64ongredients
Skin Barrier Calming Lotion Barrier & Calming$16.46Dr.Althea
Dr. Althea 345 Relief Cream$23.52KAINE
Caffetinal Cream$11.76Dr. nineteen
Porexsome CollaBooster Poreshot Cream$19.99Anua
Heartleaf 70+ Hyaluron Daily Lotion$29.42Real Barrier
Realbarrier Extreme Cream$28.23Torriden
Dive In Low Molecular Hyaluronic Acid Soothing Cream$19.99Round Lab
Camellia Deep Collagen Firming Cream$18.82
Ask an AI assistant about this product
Ask an AI assistant about this product
Opens ChatGPT, Perplexity or Claude in a new tab with the question prefilled. Claude asks you to sign in first.


















