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KOREAN PHARMACY

IOPE XMD STEM III Clinical Recovery Softener 130ml

A softener, which is what Korean brands call a first-step toner, 130 ml from IOPE with niacinamide fifth, allantoin eleventh, adenosine eighteenth and hydrolysed DNA twentieth, ahead of acetyl tetrapeptide-11 on a twenty-eight item list.

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$72.50
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Suited to
Normal skinDry skinCombination skin
Helps with
The step right after cleansing, before serum or creamShoppers who want IOPE's own Korean-market formula rather than a US-shelf version

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Key benefits

  • Niacinamide, the active this product is built around
  • Allantoin, Adenosine and Hydrolyzed DNA on the same list, actives
  • Acetyl Tetrapeptide-11 on the same list, a peptide
  • Tocopherol and Theobroma Cacao (Cocoa) Extract further down the same list
  • Allium Cepa (Onion) Bulb Extract and Mannitol further down the same list
  • Niacinamide named fifth on the manufacturer list printed on this page

Key actives

Niacinamideactive

Niacinamide is vitamin B3, and it is the most studied active in Korean formulation. On this product's own ingredient list it is named fifth.

Allantoinactive

Allantoin is a comfrey-derived compound used to condition skin and soften the outer layer so it feels smoother. It is one of the standard additions to a formula built for easily irritated skin. It is named eleventh on this product's list, alongside Niacinamide.

Adenosineactive

Adenosine is a nucleoside that Korea's own cosmetic authority recognises as a wrinkle-care functional ingredient, which is why it appears on so many Korean lists at a low level. It is used for the look of fine lines and is stable and well tolerated. The panel names it eighteenth on this product's list, beside Niacinamide.

Hydrolyzed DNAactive

Hydrolyzed DNA is DNA cut into short fragments so it dissolves and spreads. It is the same ingredient family as sodium DNA and polydeoxyribonucleotide, the one Korean formulas market as PDRN. The panel names it twentieth on this product's list, beside Niacinamide.

Acetyl Tetrapeptide-11peptide

Acetyl Tetrapeptide-11 is a four-amino-acid peptide used for the look of firmness, and it is the usual partner to acetyl tetrapeptide-9. It is named twenty-seventh on this product's list, alongside Niacinamide.

How to use

  1. Sweep or pat onto cleansed skin using hands or a cotton pad, then continue with the next step of the routine.

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IOPE XMD STEM III Clinical Recovery Softener 130ml

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How it works

The MD STEM III Clinical Recovery Softener is a 130ml product. The active it is built around is Niacinamide, named fifth on its own ingredient list. The same list carries Allantoin, Adenosine and Hydrolyzed DNA, so the active is not the only thing on it worth naming. How much of the Niacinamide stays on the skin, and for how long, is decided by the product format rather than by the list alone. IOPE sells this Niacinamide product in Korea, and this is that version.

Worth knowing

  • Patch test on a small area first and wait a day before full use, especially the first time.

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Korean-market original

The Original Korean Formula product from IOPE, 130ml formulated with Niacinamide and Allantoin, held in the United States and shipped domestically.

Verify your unit when it arrives

Verify your unit when it arrives

Korean-market stock with the original barcode and batch code intact, exactly as it left Korea.

Match the batch code on the box against the code printed on the bottle or tube itself; the two are stamped separately and should agree.

On the unit itself

  • The Korean-market barcode, unaltered from the retail package.
  • The manufacturer’s batch code, exactly as the maker printed it.

정품Genuine article, Korean-market stock

What professionals say

What professionals say

What skin-care professionals say about the key actives in this formula, quoted from the medical sources linked beside each.

  • Allantoin can tone down the dryness of the individual cells. It increases the water content of the skin, which means it helps to hydrate and moisturize.

    Wilma Bergfeld, MDDermatologist, Cleveland Clinic
  • Niacinamide helps reduce the appearance of pores in a few ways. By strengthening the skin barrier and improving elasticity, pores appear less noticeable and more even.

    Ashlyn YankeAesthetician, Cleveland Clinic
1 more professional perspective
  • It's still a very new ingredient in the field of regenerative medicine.

    Catherine ChangBeverly Hills board-certified plastic and reconstructive surgeon, Harper's Bazaar

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